<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16319

Description Uncharacterized protein
SequenceMAKAAKSEPLTIYESRPPEWLPKTHLSADLGYAGFFPPRPHQVEDTLTESNVKGGLMLGPSVPAETYSAQDSIRKRLMQENALSELEDLMNQVFARKAESVPGIPASSFRLPSRVTLNDAKRQAWFADLANPDVPLSKLGKNVPHGAKGHDLLDLLHTNNVAIPRAVWFLRVFGANESAGLRNKPSYNPTQYSIEWANVMTTYLKKQLADIALPSAPRPGLSIKQTFKGVLSDTGTREKWISRFTYCLSLLRTFYAEGLVDNRTFLSWLVQQMATCNLAQLGFVARLADEYLEGMLVSRALTHPFTEACLGKFAEIQSTHAKEHLANTTNILRSLISRSFLALPDASVSPRMHTQFGSKLEEILLDDFAAEGSDTSLQPNIQALHQIVLDTLSDVQRRNEAMLFHHLPPRVLGTLSSALSDIKLLNSISGKTDMPSVALFDDTSDISDTFTRKLDFLLTWSVTPLQYGDHRPYAAACLLQLWRNKAEERAIRRDAPLPDDQIQSLIFHWLNKSEVAGEPSNLPAVALLFGQLVKHGLFSYGAYMQHLVARGEEGLSYTTPQGEVSRHREFLRWIPLHEPSSSMMSERKAILYGLRMRETPEEANEKEIRRELRLLLPEPFGGEAPAGEPLTTTFWQSCNNLLSAPRFEQVKIIKQWFLPIYKRWLSSHKNLNIDSEVLVLRVYTLTVVIMARMRSYGSILDMSLCTLEYATASPLLNAVIETLRQHMEVWACMNRMKTVAVALWTVHQTWRSRGSQNRVLLKLLAEVDNDTYLEPAAREQMLSDISAYTHALFPTNENPGNVPPVLPEILMLATDSTPEAPSLLANSLWYKYMTSPDWAWKVWDNTIASLRQLPAMMPDIPSRRACALRYAAFLLHVDQHLPRGFDEQIRSWLMGSGRSEIAALTTETWDVVTVVLLYLNCYGALATTTILESLVFQVWQAGANVSSEEQGQALETLLTSVNTLFEHLLLRDECGTGLPPVDVFEAQGLLTRRRDVFREPHFSMLVSNFPALVLIEQNRFLSETLRTASTTLRKTICRVNVFRQGIYRDLDAVRITFEKLLESQSIPDDLHEPLVGALRLMLNDPGQDGPVNAADLHSVSSLLSHWKLAATSVEIRLTIKQLQEGISREPTRVAAYASLDRLTSAVFYSCRQPEEADFIADLIIDVDRTVAGKFVNAGLRRVSEIFREWDPLLDNRTHNDLKKCASEILRLMANIVAPFRKDASLPQLDPLIQETFFAVLCVKIKKMTEIMATLLQNPWEEEAARGTQAIVFMARVLQFHLGFSITWSQQAKEHAEELCFNLTRLALMHGAGESLNMLVFPLVLDTLCYTLDEIPMDVKATAPFDPFRNYPEFNLSDLPADMPPEYKARMRSLLPYVELNPAVEGLVYITRDASGAIVGSVPVQNRPWEWTEYIGDNPAGEMSRGGDERVPDDRPHVRNSAALSLDLFEARVTGDRVILPPKQVHQGFLAGVEDMMAEENLRSFQDDVFSEGPFRRDWRETRIPFDDAIGSNPSGRRNSPQDDDNINTMTPLPALSGHAVATGVSEHRPSSRRPSPASSGR
Length1561
PositionKinase
OrganismGanoderma sinense ZZ0214-1
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Polyporales> Polyporaceae> Ganoderma.
Aromaticity0.08
Grand average of hydropathy-0.202
Instability index52.54
Isoelectric point5.80
Molecular weight175365.41
Publications
PubMed=26046933

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16319
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.28|      26|     124|     698|     725|       1
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  698-  725 (35.65/33.18)	SILDMSLcTLEYATaSP.....LLNAVIETLRQ
  822-  852 (43.63/28.56)	SLLANSL.WYKYMT.SPdwawkVWDNTIASLRQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     297.58|      89|     128|    1057|    1151|       2
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  470-  509 (24.42/ 7.10)	..............HRPYAAAclLQLWRNKAEERAIR.RDAPLpdDQIQSLIFHW.............................................
 1057- 1151 (132.83/100.12)	FEKLLESQSiPDDLHEPLVGA..LRLMLNDPGQDGPV.NAADL..HSVSSLLSHWKLAATSVEIRlTIKQLQEGISREPTRVAAyaslDRLTSAVFYSCR
 1189- 1275 (140.34/88.25)	WDPLLDNRT.HNDLKKCASEI..LRLMAN...IVAPFrKDASL..PQLDPLIQETFFAVLCVKIK.KMTEIMATLLQNPWEEEA....ARGTQAIVFMAR
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.78|      38|      41|      86|     126|       3
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   88-  126 (62.84/53.23)	DLMN.QV.FARKAESVPGiPASSFRLPSRVTLNDA..KRQAWF
  128-  169 (53.94/33.47)	DLANpDVpLSKLGKNVPH.GAKGHDLLDLLHTNNVaiPRAVWF
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     249.00|      81|     112|     195|     299|       5
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  195-  299 (126.76/127.62)	EWANVMTTYLKKQLAD.............IALPSA...PRPGlsikqtfkgvlsdtgtrekwiSRFTYCLS..LLRTFYAEGlvdNRTFLSWLVQQMATCNLAQLGFVARLADEYLEGMLVSR
  312-  410 (122.25/79.74)	KFAEIQSTHAKEHLANttnilrslisrsfLALPDAsvsPRMH.....................TQFGSKLEeiLLDDFAAEG...SDTSLQPNIQALHQIVLDTLSDVQRRNEAMLFHHLPPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     128.49|      29|     173|     777|     805|       8
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  532-  554 (31.42/16.22)	LVKHGLFSYGAYMQHLVARGEEG......
  777-  805 (49.74/30.26)	AREQMLSDISAYTHALFPTNENPGNVPPV
  953-  981 (47.34/28.42)	ALETLLTSVNTLFEHLLLRDECGTGLPPV
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     201.54|      60|      94|    1362|    1428|       9
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 1362- 1428 (96.45/85.93)	MPPeyKARMRSLLPYVELNPAVEGLvyitRDASGAIVGSVPVQnRPWEWT.....EYIGDNPAGEMSRGGDE
 1459- 1523 (105.08/71.01)	LPP..KQVHQGFLAGVEDMMAEENL....RSFQDDVFSEGPFR.RDWRETripfdDAIGSNPSGRRNSPQDD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16319 with Med12 domain of Kingdom Fungi
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