<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16310

Description Putative mediator of RNA polymerase II transcription subunit 24
SequenceMDAQQTYTAVQELLLRAWKERLPDIQWSIQMKRVLKGATIDGYTLCVRCLLVPTLPLYYLLLEALHLPKMVSHVAVLRSLAKYENTCVTRPFCMKSLLEILKLCVVKISCLGPPDECLQIAVALLQVILWLVKSICLSLEKIAENGSSIQIVTNLMQMCELLYGICAQDQTRMLLYIARLEDEALWSQLEGEIASVSTIVNNAHASGTNRGNHLEQALNSNRQQPSPQRKDGKERTVNETLKFKLERALDSALKVPNCSYSGKYLPTTHSMEYYTGYVNCYVNIMTFIETHLTITHDPQLFVDQILLYEKLQNLSRKQLYTSLCQGALLGLVDSSDDTDQIRSFAFLFLKLPKILSYLHHNVSSIDPNSSALYHGLDNLLQYVSLIDSADTKHKCDCFQQFLSQLVKLELLNETQATELMAKRQASRHSPADTTPQQHLVIQANSTLPTILDSLEVPDKSVLDEMPNVFHPLMNSFQLVAATSAATNKLKTFSSKLISFNELTKATVIDGSKGSHVQAALYDISFLMLCLISQQYGIELVNTGQFQADSLGRSSLGYQCHFTQQMVLNNDEESFFERWAQQCLPDELGAKPMYLPLAQTEQMKIDQLVQLFYTSGDIKAIKLQGICSEMFSLGVCAAAWLHSNAVGVDASGDSKVWAFFEMFLEPKPSQKVDFHFNNTERIAMMTSVIEKMKSHSSGTSEKAQEYGSNPSLASKDPSTFLFSSAFQEIMVRKVLFKRLQPQLEMMFNMSGVTWICWSVISEVLKLNRRDDLALAGGQRATHHRSPEKSPAPTTLRSQPQQQHHRPRGRALAKLTVWCIASTLTTQNSYRADPKAKENPMRIRKRKRTRGEPDRDSTSTLREDNRPSKLRRLLSIPEDENAASGLNSTTLSTTSNPLLVPQTSTQLGEPLYKAIASMMQLFASVLSENALSSRTEFIYSFLQEILTCGDAVSSTVLQFMPVSMANHLFSTINKNFIQDLALAIETLDSVVARRQAARALCIMGR
Length1003
PositionTail
OrganismStichopus japonicus (Sea cucumber)
KingdomMetazoa
LineageEukaryota> Metazoa> Echinodermata> Eleutherozoa> Echinozoa> Holothuroidea> Aspidochirotacea> Aspidochirotida> Stichopodidae> Apostichopus.
Aromaticity0.07
Grand average of hydropathy-0.148
Instability index41.31
Isoelectric point7.72
Molecular weight112579.42
Publications
PubMed=29023486

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16310
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.26|      24|      56|     331|     354|       1
---------------------------------------------------------------------------
  331-  354 (39.93/29.80)	LVDSSDDTDQIRSFAFLFLKLPKI
  385-  408 (42.33/32.10)	LIDSADTKHKCDCFQQFLSQLVKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.06|      12|      21|      76|      95|       3
---------------------------------------------------------------------------
   76-   94 (13.57/30.33)	VLRsLakyentCVTRPFCM
  100-  111 (21.49/ 8.94)	ILK.L......CVVKISCL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.85|      14|      21|     469|     482|       7
---------------------------------------------------------------------------
  469-  482 (25.97/15.38)	FHPLMNSF.QLVAAT
  492-  506 (18.88/ 9.29)	FSSKLISFnELTKAT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.58|      19|      28|     214|     233|       9
---------------------------------------------------------------------------
  214-  233 (29.94/21.64)	LEQALNSNRQQPSPqRKDGK
  245-  263 (33.65/19.65)	LERALDSALKVPNC.SYSGK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16310 with Med24 domain of Kingdom Metazoa
Unable to open file!