<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16304

Description Putative vacuolar protein sorting-associated protein 13A-like
SequenceMKSASSRPLTDDYDQENLWTPKPIFSHGFQRRKGSMKNMVDFAPVPEPSSTPTQKLTVQMPRLSVCLELEAARDHLSVMIFQIRMRTLVFDWSACMRAEMEMTLEGMIYNEKISLWEPFLEPVLEDEDDYTPWELLIKLVKADSHPILCSSPYDSLAPGIKDSLDGPGFGGTRSLESYPVTETETDSDSQSDTELEWDGHYSSSLLSSDLATPQDEEKPLPQDTIPSEDQEDSDSEEVDGFFGKVKGFFQDIFTSESDSEAEEAMESAASARENLRRSDSGIASSLRLTSSTLASSDGKDEVDADEDLQDVESTATYLIINATEKLDISVTPWSIDVLQNLINQYSSPPPAGDVVTLLKEEAMDVTIINTAGISGKIITEVTNEDKISSSGITLITSPSGSHDHMDAAGLETAPLGENERRSRYCSSCPFRAVGDSTDHAGDRSSEAIVEDARLELTNHCQIPLELSYKKLDLQSLLGASIPGEEQNEFTSIGVVQPQQTMDIPLLVAYHAGIYACPVDRGFQPNDQPIKWYEIQDPAELTYQCPPIKEGSPLSFFFRVTREVLKLDKPSSVSRAPTYILHIHPPITLHNFLPYDLVYSFLDTGLKFLLRGEKMDVHSVDLNQGQTMTMQVKSYLSSNWEGTLMVSREMKATETVAMVMQTTGNNQKHLNLLANSTSTDGAWDIFMYSPYWIVNKSELPVEIRASRSRKVFSTHSLADPVLFNFSSTKRRKAKLRVFDSVWSTSFSLDTVGSSGVIICRDEDHDRTYQFWMDIRLSNLSLTKIVTLMPYFLIQNHTDITLSYVEEGVKAGVWVNIKPGEVLPFWPGTLSMKLLARKATTPDILTSRPFSISTPNTTVLRMERGSALTVQVEGGIQGPTTVTFCQYSTGQAPVRLDNLCDDINLRFNQKNVGGRLLLRPHQSMLYTWDDPSADRVLTWNLYNRNKISFDCIMNRDSWGKVVISMDSINRSMLPGDGLYVEGDDASVYSTDEEEDKSEVDGVIEHPLMARKERTNVFWVSYMDGLQRVFMVTQSSKIARLATQAYVSEQAKLELFASINGVGLSLINAHYEEVAYISLFSSPAKWEVETKPDKWKALTMELSGLLEDRFKQGEEKVEIEGALEADFKSNMISKPVAGPLRRTYNPGVWFHLRQSDHFTSVHFKLHKIQIDNQLFDAYFPTVMSVNPLPSEVLKKTGPKPFIEMSLLRKNIPEAGLDTIKYLKVLIQESSIRVDDGFLRSVLDIFSNLKQEEEEIFSLHADLDFIQTSLRETSTTDNTMTKMFFEYLHLSPLKCIVSFSLAGQPHLVNPKTTNGLLKFFLDSIGSTLTEVSEVELKLAYFERTNILVTQSQLLADAQDHYVSQAVKQAYVFILGLDVLGNPYGLFRDVKEGISDFFYEPYLGLIQGPGEFAEGLAKGVQSLLGHTVGGVADTLSGLSGTVGRALAFISFDEDYQKARIRRLQRHPDSLPKHLLYAGQGFVMGVIVGLTGIVSSPPRSTGRGSEGVLQRSRQRSLGFGDQTVRYPQCLHFLELLQYESFRKELANAQCVRFIEDQQLLHWQHYSYKRMRLQQSHLDNLHQQHAQQQQQQQQQQSNQQQTTQQQSGMLPPPQQQPASSQAAGLPFAGLQPQHHQSGQVPLQSQTRLLQMDQKPLQSLPQNSLNTK
Length1660
PositionMiddle
OrganismStichopus japonicus (Sea cucumber)
KingdomMetazoa
LineageEukaryota> Metazoa> Echinodermata> Eleutherozoa> Echinozoa> Holothuroidea> Aspidochirotacea> Aspidochirotida> Stichopodidae> Apostichopus.
Aromaticity0.08
Grand average of hydropathy-0.359
Instability index48.00
Isoelectric point5.09
Molecular weight186287.15
Publications
PubMed=29023486

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16304
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.92|      15|      15|    1567|    1581|       1
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 1567- 1581 (28.59/14.31)	QQSHLDNLHQQHAQQ
 1583- 1597 (24.33/11.10)	QQQQQQQSNQQQTTQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.94|      13|      15|     923|     935|       2
---------------------------------------------------------------------------
  923-  935 (24.38/17.71)	LYTWDDPSADRVL
  939-  951 (24.56/17.92)	LYNRNKISFDCIM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.67|      11|      15|    1098|    1108|       3
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 1098- 1108 (19.42/10.11)	ELSGLLEDRFK
 1115- 1125 (19.26/ 9.97)	EIEGALEADFK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.54|      13|      15|    1490|    1502|       4
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 1490- 1502 (24.74/13.28)	SPPRSTGRGSEGV
 1506- 1518 (23.80/12.49)	SRQRSLGFGDQTV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.64|      12|      15|     391|     404|       5
---------------------------------------------------------------------------
  391-  404 (18.22/15.18)	GitLITSPSGSHDH
  409-  420 (21.42/10.95)	G..LETAPLGENER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.13|      14|      15|     104|     117|       6
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  104-  117 (25.73/13.63)	LEGMIYNE.KISLWE
  120-  134 (22.41/11.00)	LEPVLEDEdDYTPWE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.41|      37|     313|    1012|    1068|       7
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 1028- 1068 (48.35/64.27)	MVTQSSKIARlATQAYVSEQAKlELFASIngVGLSLINAHY
 1343- 1379 (64.06/30.61)	LVTQSQLLAD.AQDHYVSQAVK.QAYVFI..LGLDVLGNPY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      25.73|       9|      15|     302|     311|       9
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  302-  311 (10.79/11.24)	VDADEDLqDV
  320-  328 (14.93/ 8.82)	INATEKL.DI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.01|      37|    1139|     240|     292|      11
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  186-  224 (58.33/42.76)	DSDSQSDTELEWDGHYSSSLLSSDLATPQDEEkpLPQDT
  256-  292 (56.68/21.65)	ESDSEAEEAMESAASARENLRRSDSGIASSLR..LTSST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.60|      31|     243|     739|     772|      15
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  739-  772 (56.20/41.08)	SVWSTSFSLDTVGSSGVI....ICRDEdhdRTYQFW...MD
  984- 1021 (47.39/26.48)	SVYSTDEEEDKSEVDGVIehplMARKE...RTNVFWvsyMD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.17|      25|      27|    1599|    1625|      17
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 1599- 1625 (38.06/30.27)	QSGMLpPPQQQPASSQAAGLPFAGLqP
 1629- 1653 (45.11/25.64)	QSGQV.PLQSQTRLLQMDQKPLQSL.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.08|      28|     194|     586|     616|      19
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  586-  616 (43.71/34.99)	ITLhnfLPYDLVYSFLDTGLKFLLRGEKMDV
  784-  811 (49.37/30.19)	VTL...MPYFLIQNHTDITLSYVEEGVKAGV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16304 with Med31 domain of Kingdom Metazoa
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