<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16288

Description Putative mediator of RNA polymerase II transcription subunit 13-like
SequenceMQRTPGSAEPPQANESPPSNAPSPLNPPPNGILGNPMDQPMPTLSPNPPPRSSSDSLGGIGSIASFRAELNGIIDLAKSDPSPKQPLVGELSVPKEEEEEDVWSCFELPSVEGDGNSKRPRLPSMPHSQEDLQDGNLENLYEHDNSGERFSQPHKRLRQERRTRSCLDSNVFSLQNDVDTLQRVKTPDFDPYEFMDTSPTEVDLVPPGARAKMARGSREVCNKEETVLKKERNSSEFVITIDNPICKEEEAQRKAEGEKARQEAMTPMNVSYPNEPFKMGDFGVPLLPRPESSSLTTEKDLQITLNDFESLFESSDEDDDRVPLTNVSSDFPCGANSEENLSTRTLFGSSISSSSMSGPLTGGDLGRMYPTPPSEEQTHFSPVNHPCPELSSNLTSYGSNQTRDMTSGPMNEQFEIEIEESLCSPRPEPLLDWTYVYKVPAVEKIVGATMYAP
Length453
PositionMiddle
OrganismStichopus japonicus (Sea cucumber)
KingdomMetazoa
LineageEukaryota> Metazoa> Echinodermata> Eleutherozoa> Echinozoa> Holothuroidea> Aspidochirotacea> Aspidochirotida> Stichopodidae> Apostichopus.
Aromaticity0.06
Grand average of hydropathy-0.820
Instability index68.85
Isoelectric point4.51
Molecular weight49950.62
Publications
PubMed=29023486

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16288
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.95|      12|      23|     220|     231|       3
---------------------------------------------------------------------------
  220-  231 (20.36/15.50)	VCNKEETVLKKE
  245-  256 (20.60/15.77)	ICKEEEAQRKAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.19|      30|     118|     173|     206|       4
---------------------------------------------------------------------------
  173-  206 (39.92/36.77)	SLQNDVDtLQrVKTPDFDpyEFMDTSPTEVDLVP
  294-  323 (51.27/29.03)	SLTTEKD.LQ.ITLNDFE..SLFESSDEDDDRVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.78|      17|     134|     274|     291|       5
---------------------------------------------------------------------------
  274-  291 (29.67/19.61)	NEPFKMgDFGVPLL.PRPE
  411-  428 (28.12/13.72)	NEQFEI.EIEESLCsPRPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.19|      27|      51|     330|     360|       8
---------------------------------------------------------------------------
  330-  360 (40.30/31.07)	DFPCGANSeENLSTrtlFGSSISSSSMSGPL
  384-  410 (52.89/28.57)	NHPCPELS.SNLTS...YGSNQTRDMTSGPM
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16288 with Med13 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DVDTLQRVKTPDFDPYEFMDTSPTEVDLVPPGARAKMARGSREVCNKEETV
2) EEEDVWSCFELPSVEGDGNSKRPRLPSMPHSQEDLQDGNLENLYEHDNSGERFSQPHKRLRQERR
3) ICKEEEAQRKAEGEKARQEAMTPMNVSYPNEPFKMGDFGVPLLPRPESSSLTTEKDLQITLNDFESLFESSDEDDDRVPLTNVSSDFPCGANSEEN
4) MQRTPGSAEPPQANESPPSNAPSPLNPPPNGILGNPMDQPMPTLSPNPPPRSSSDSLGGIGSIAS
5) STRTLFGSSISSSSMSGPLTGGDLGRMYPTPPSEEQTHFSPVNHPCPELSSNLTSYGSNQTRDMTSGPMNEQFEIEIEES
177
98
245
1
342
227
162
340
65
421










Molecular Recognition Features






MoRF SequenceStartStop




1) EEEEDVWS
2) FDPYEFM
3) FESLFE
4) SKRPRLP
97
189
308
117
104
195
313
123