<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16282

Description Uncharacterized protein
SequenceMNEDWKTPQHRRKIVEQIERKIQNPNKAREVEKASFSKAKTKEEYFIMVKNLLTHITGAKKENMVNMQQTTAGHNNVQDAMMAMQNLPNRGQGLAGNQQQQLQMGQPGMPGIQQTLQGQQQHINIQQNQLNMMRQKQLQQQQQQHTLQMHMNQQQQQQQSVTIQQQQQPGMPAFNPNNMNQPQQIIRTAANFVSPTGQPPQNPMAPPAAPVFPGQPTPPQHQAKGIYAKVMCVHACILCRAMAIWGQQVGLGQFRLVP
Length258
PositionTail
OrganismStichopus japonicus (Sea cucumber)
KingdomMetazoa
LineageEukaryota> Metazoa> Echinodermata> Eleutherozoa> Echinozoa> Holothuroidea> Aspidochirotacea> Aspidochirotida> Stichopodidae> Apostichopus.
Aromaticity0.04
Grand average of hydropathy-0.876
Instability index68.71
Isoelectric point10.12
Molecular weight29270.27
Publications
PubMed=29023486

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-KW
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP16282
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      97.25|      14|      15|     130|     143|       1
---------------------------------------------------------------------------
   94-  107 (23.05/ 6.24)	LAGNQQQQLQMGQP
  109-  121 (23.77/ 6.70)	MPGIQQT.LQGQQQ
  130-  143 (26.81/ 8.64)	LNMMRQKQLQQQQQ
  171-  184 (23.62/ 6.61)	MPAFNPNNMNQPQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.82|      11|      17|     190|     201|       2
---------------------------------------------------------------------------
  190-  201 (19.91/12.77)	ANFVSPtGQ..PPQ
  208-  220 (19.91/ 8.24)	AAPVFP.GQptPPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.45|      16|      17|      39|      55|       4
---------------------------------------------------------------------------
   39-   55 (23.06/18.37)	AKtKEEYFIMVKNLLTH
   59-   74 (28.39/17.73)	AK.KENMVNMQQTTAGH
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP16282 with Med15 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MNEDWKTPQHRRKIVEQIERKIQNPNKAREVEKASFS
2) TGAKKENMVNMQQTTAGHNNVQDAMMAMQNLPNRGQGLAGNQQQQLQMGQPGMPGIQQTLQGQQQHINIQQNQLNMMRQKQLQQQQQQHTLQMHMNQQQQQQQSVTIQQQQQPGMPAFNPNNMNQPQQIIRTAANFVSPTGQPPQNPMAPPAAPVFPGQPTPPQ
1
57
37
220

Molecular Recognition Features

MoRF SequenceStartStop
NANANA