<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16271

Description Putative mediator of RNA polymerase II transcription subunit 26 isoform X1
SequenceMPYLAFLILQVVNTGGVTKAILALEKMTLTKEALEGTRLGRLVNDIRKASTDDKLRERCRRLIQKWKNQFVGSIKSKPADGRGSPTTSQLKQKSASKSSPKAGSLISQTPVTTGGTPVDQTKSENRKRRKPDSATSSPEDKRPPKKQQIVDSAKQKTKEHSAKDGIKRREDSVTDQTDSCPPKVVIGKAGKTRSSKVKSNDGNKETKSLHKLVVVSNATKAVGIVEKKQSQNQPKTSQSKKSPKGARHGINSGSSSSSSKRNGSAGDSLPSQSLRYEETNQTSVLSPHRVIAASPESVSYDENTQDSYDESGEVSLFDMDKEEEDEERQDTLDELTMSSMPDSPITSQDSGSSQHSHGSNQMSDIVDDTTRVAEELVEEEGPPVRSREVKVEDVNRLHDEHWEGMNGNFNSDGGWSSWDSCFSVRHGWREQSSYTTICMHRLTIATQ
Length447
PositionUnknown
OrganismStichopus japonicus (Sea cucumber)
KingdomMetazoa
LineageEukaryota> Metazoa> Echinodermata> Eleutherozoa> Echinozoa> Holothuroidea> Aspidochirotacea> Aspidochirotida> Stichopodidae> Apostichopus.
Aromaticity0.03
Grand average of hydropathy-1.012
Instability index62.41
Isoelectric point8.88
Molecular weight49161.81
Publications
PubMed=29023486

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16271
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     257.67|      67|     149|      71|     138|       1
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   71-  137 (110.29/50.29)	VGSIKSKPAD...........................GRGSPTTSQLKQK...........SA.SKSSPKAGSL.............ISQTP......VTT.....GGTPVDQTKSENRKRRKPDSATSS
  150-  220 (31.98/ 7.10)	VDSAKQKTKEhsakdgikrredsvtdqtdscppkvviGKAGKTRSS.KVK...........S..NDGNKETKSL.............HKLVV......VSN.....ATK.....................
  222-  315 (75.81/31.60)	VGIVEKK..Q...........................SQNQPKTSQSKKSpkgarhginsgSS.SSSSKRNGSAgdslpsqslryeeTNQTS......VLSphrviAASPESVSYDENTQDSYDESGEVS
  336-  384 (39.58/14.13)	..TMSSMP.D..............................SPITSQDSGS...........SQhSHGSNQMSDI.............VDDTTrvaeelVEE.....EGPPV...................
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16271 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FVGSIKSKPADGRGSPTTSQLKQKSASKSSPKAGSLISQTPVTTGGTPVDQTKSENRKRRKPDSATSSPEDKRPPKKQQIVDSAKQKTKEHSAKDGIKRREDSVTDQTDSCPPKVVIGKAGKTRSSKVKSNDGNKETKSLHKLVVVSNATKAVGIVEKKQSQNQPKTSQSKKSPKGARHGINSGSSSSSSKRNGSAGDSLPSQSLRYEETNQTSVLSPHRVIAASPESVSYDENTQDSYDESGEVSLFDMDKEEEDEERQDTLDELTMSSMPDSPITSQDSGSSQHSHGSNQMSDIVDDTTRVAEELVEEEGPPVRSREVKVEDVNRLHDEHWEGMNGNF
70
409










Molecular Recognition Features






MoRF SequenceStartStop




1) WKNQFVGSI
66
74