<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16266

Description Putative mediator of RNA polymerase II transcription subunit 25-like
SequenceMQCPGKFSSSERNVNMSVISPRKLYELQQLYDKACGELQVLTTKEYALDQRHLILLRGYELQERSPAVELKEVKQDLLSPRKQPNNLVSMSAASSVAVASTSMNFTPSNVNTLLTAQSILSHKGQQQQQPIPTQAAVTINMKPKMSVASMQRDVQDKQQVAGSIAGQVQPNQTMVQQQAQQQLQHQQQQQQQHQQQQMSVLPALQQQQQAVRLPQQQQQQHAGIQHVHQAIAQQPQQLQSVMQPQQIPNIQQPQLSLAQLPGKKGLTKEGFLKMMQALPPEARKKFIEDLKVRKNQQQQQQVTSQAAGLVNSQTAASSSAVDLIQPNITIAKPQSSQNIGAATATVQGIPTSTTAGLAPMSAVAAARDVVRIAGVTVSNSRLPNQGGQGFNPQQPNNPLLSNHLQQSGMPQQQQTSLQQQQQQQQASLQQQQQTTLQQQQNVNLQQQQQNAMQQQPGMPQQQANLQQDQLLNQQATMPSVSNMVFQPDQAGNVMSQTIVQQNNPPLVAMNPVNRAGVARPLKILWNGVLEWHERTKTSTMTQDQRIQHCINCSVSADPIPTSTATVGQRNLPCRSFHLNFWVLTLRHGDTSSGFFHSQFAGCIHLSSEVQSDTSIRVLLLWYIKASDQFKGRIPKDQAGFINNFRELIKKHQQEQQQKQLQQQQQQALIGARPQMQVPGMIQRPANMTQVMGPRNPIPPVAASNGQVLSQKDLQEFVKRLQQQKQQQHQQQQQQQQQQQVQQQQSNQQLLQQAQQMSQVGIRPQGMVGQQQQQQVPTQTQQLPSNNAQLKNLLLNQAQAQSQGGQLQWNQPQQLGQQQQLGQQQQLGQQQQQLGQQQQQQNLLLQPQQLQQAAVAMGQQQRMPQRTMSQVMQQGGGFAQGITVQGGSMGGQRAILQQGMNPQGMQGMGKPMPRQQQQQQQQQQQQQGGKGGLRDDLSLMDLLQP
Length944
PositionUnknown
OrganismStichopus japonicus (Sea cucumber)
KingdomMetazoa
LineageEukaryota> Metazoa> Echinodermata> Eleutherozoa> Echinozoa> Holothuroidea> Aspidochirotacea> Aspidochirotida> Stichopodidae> Apostichopus.
Aromaticity0.03
Grand average of hydropathy-0.817
Instability index73.73
Isoelectric point10.15
Molecular weight105244.48
Publications
PubMed=29023486

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16266
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     174.84|      27|      27|     167|     193|       1
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  167-  193 (52.45/11.12)	QV.....QPNQTMVQQQAQQQLQHQQQQQQQH
  397-  426 (40.54/ 6.18)	NPllsnhLQQSGMPQQQQTS.L.QQQQQQQQA
  427-  450 (40.17/ 6.03)	SL.....QQQQTTLQQQQNVNL....QQQQQN
  828-  852 (41.68/ 6.65)	QQ.....Q..QQLGQQQQQQNLLLQPQQLQQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     421.22|     146|     618|     124|     326|       4
---------------------------------------------------------------------------
   17-  206 (121.98/31.94)	......................S.........VISPRKLYEL......QQlydkacGELQV..LT.TKEYALDQRHLILL..RGYELQERSP...AVELKEVKQ..DLLSPRK...QPNNLV.SMSAASSVAVAStsmnFTPsnvntlltaqsilshkGQQQQ.........Q......PIPTQAaVTINMK..PkMS.VASmQRDVqdkQQVAG.SIAGqvqpnqtmvqqqaqqqlqhqqqqqqqhqqqqmSVLPalQQ
  219-  385 (214.30/55.22)	QQHAGIQHvHQAIAQQPQQL.QS.........VMQPQQIPNI......QQ......PQLSLAQLP.GKKGLTKEGFLKMM..QALPPEARKK...FIEDLKVRK..NQQQQQQvtsQAAGLVnSQTAASSSAVDL....IQP..........nitiakPQSSQnigaatatvQ......GIPTST..TAGLA..P.MSaVAA.ARDV...VRIAGvTVSN................................SRLP..NQ
  453-  572 (84.93/ 8.97)	QQQPGMPQ.QQANLQQDQLLnQQatmpsvsnmVFQPDQAGNVmsqtivQQ....nnPPL.VAMNPvNRAGVARP..LKILwnGVLEWHERTKtstMTQDQRIQHciN..................................................................csvsadPIPTST.ATVGQRnlP.................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     145.03|      49|      95|     669|     723|       5
---------------------------------------------------------------------------
  692-  789 (52.66/17.35)	GPRNPI..PPVAAS.NGQ..VLSQ....KDLQEFVKRL....QQQkqqqhqqqqqqqqqqqvqqqqsnqqllqqaqqmsqvgirpqgmVGQQQQQQVPtqtQQlPsnNAQ.L
  790-  871 (48.39/11.27)	..KNLLlnQAQAQS.QGG..QLQW....NQPQQLGQ......QQQ.........lgqqqqlgqqqqqlgqqqqqqnlllqpqqlqqaaVAMGQQQRMP...QR.T..MSQvM
  876-  925 (43.98/ 6.40)	GFAQGI..TVQGGSmGGQraILQQgmnpQGMQGMGKPMprqqQQQ............................................QQQQQQQ................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      66.89|      19|      26|     573|     591|       7
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  573-  586 (21.47/14.53)	.....CRSFHLNFW.VLTLR
  587-  606 (30.92/24.32)	HGDTSSGFFHSQFAgCIHLS
  610-  621 (14.49/ 7.30)	QSDTSIRVLLL..W......
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16266 with Med25 domain of Kingdom Metazoa
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