<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16262

Description Putative mediator of RNA polymerase II transcription subunit 13-like (Fragment)
SequenceDHLSFKLSFFLHGESTVCSSVDVSQHPPVTKLTPEHLEATANGYSNGFQVILAPYGLNAVLYGQNYKGNSEQNQKAWQVLLEWSHFYPIKNPQSSTLFGAESEDVEGTMPPAVEVFVGGVRMLYPSCYVFVVQDDMSNVLMQQQQQQQQQQQQQQQQQHHNPTSAVSPMPMAPSLNVLSPMPMAATPGQSYPNTAQGNTSVCSAPSSPQDAVYPIGESSTHYPQRTMVDACVGTAGDMDGGSFTHQLTQKVWKEWLAETDKSPIFRTNASKSTAPDTPGSETTDIHKPVNHEEGTGPSAGSSEAKESNQAPPMWSFSDPTVKADCKCHRQKFLKSKQSVPFGKTPPGPGNSHMSSGLGSNSLGPSSKHKADNRTEKMSRNSQFLFT
Length386
PositionMiddle
OrganismStichopus japonicus (Sea cucumber)
KingdomMetazoa
LineageEukaryota> Metazoa> Echinodermata> Eleutherozoa> Echinozoa> Holothuroidea> Aspidochirotacea> Aspidochirotida> Stichopodidae> Apostichopus.
Aromaticity0.08
Grand average of hydropathy-0.664
Instability index55.68
Isoelectric point6.05
Molecular weight42025.16
Publications
PubMed=29023486

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16262
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.78|      28|     158|     182|     211|       1
---------------------------------------------------------------------------
  182-  211 (48.03/27.46)	PMAAT...PGQSYPNTAQGNTSVcsAPSSPQDA
  340-  370 (47.75/21.65)	PFGKTppgPGNSHMSSGLGSNSL..GPSSKHKA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.40|      29|     174|      74|     105|       2
---------------------------------------------------------------------------
   74-  105 (51.85/37.64)	QKAWQvllEW...SHFYPI..KNPQSST...LFGAESEDV
  249-  285 (39.55/21.73)	QKVWK...EWlaeTDKSPIfrTNASKSTapdTPGSETTDI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16262 with Med13 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KSKQSVPFGKTPPGPGNSHMSSGLGSNSLGPSSKHKADNRTEKMSRNSQFLFT
2) LMQQQQQQQQQQQQQQQQQHHNPTSAVSPMPMAPSLNVLSPMPMAATPGQSYPNTAQGNTSVCSAPSSPQDAVYPIGESST
3) PQRTMVDACVGTAGDMDGGSFTHQLTQKVWKEWLAETDKSPIFRTNASKSTAPDTPGSETTDIHKPVNHEEGTGPSAGSSEAKESNQAPPMWSFSDPT
334
140
223
386
220
320










Molecular Recognition Features






MoRF SequenceStartStop




1) PTVKADCKCHRQKFLKSKQSVPFGKT
319
344