<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16236

Description Uncharacterized protein
SequenceMPKANDTIKSHIKVIHEAALNFDPKNMGMLAVLANAFKSDTRIGAQIVPAMSEALNTPPDPSQPTFDLSYQRKAVNQFDAFPKEFLDALTSRAKRSLLLQILNVFRSFGTDKLPSPAAFETLARICQSEDYEMAVKDLESLASRSLHISTQERAADSATNNQAKDQCHFLFDFLAYRLPHVHSYGKYTSTTGALLHYFTASVAPNTPQNHQVYRLLEQALLRRMYWRTFHESVINHSQLFGSGYKENSNNVMLRHLMKPKTFSRPEDQWQFPLNPEFFKMTIYAFMRALKITGQEISVDGTMHPIHVEGYGWPEKSISFFPKWALEEIKKTDVKKLTPNYAEILSTTDEAFRMNTLLTGPQYVIRYADDPNPITYHCMLAVIFKQLCAKPDEDLTSEYYQVMEKKSPKDIVVMGNYLVDFIIADVKNNQDVNEQTFKTIAKTAALMCFHSNVHRADRFLLSLIMHPSTDEDAQICIQIANEFLLTPEFQKRIKWFYENEVPKKEKDPYEYIRAIVKYHDAFPEFEACEVVPKNDATGTNVHMPTYYGCLIERLLPILDQYVYVALEQQGYKMSNALLQLVSMFYKYHPMPIHFMYSVLFVSHGKMAGPDAKSFVSAFASQIEECHLTEEFEKYNHQKSSCEELIMELLDRMAASLDFVLTPPTFVAKDWRTAEMSPGAQALYLACIELMASPHSPEKLVNAMINVMQMRPHLRPFNVFNLIALLLTALPSTYADALHEEFIGVFKNGETANLKFEEIVFDNYDSSLLLHLPNRARSINMIAQIYWTQCNMALLNPFANDQVPKLLEHVKTEKDLWYTLRLVMPIIRRFWDSWDFAKTMRALRERFGPLVIMKLIIEKLGSMAESGVEIVHEAPFCDLFYNCKYVFVGDFLRETAITEFAKLPEAMRERLKYYVSQNEPAPPETPEREKTPERRDQQKEQQEAVPNLAPQPNHPHLLHQQQPHQQHHQNPIHQEAHQHHPHHPQQHQQPSMPPPQLIPQHHLQHHQQLHHQQQQQHLSQMMPPPQQPLQHLPHHPMDMPPPTSAPMHHQQHQMAMHQQMYPGQMFHHPQGGHMGYGMQHHMQQPHPHHPQMQGQMPGQMQHMMHNMTPQQQQQYAYMMQQQQHHYMQQQHQHQQHHHM
Length1137
PositionTail
OrganismCaenorhabditis nigoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.10
Grand average of hydropathy-0.514
Instability index53.65
Isoelectric point6.49
Molecular weight132157.90
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16236
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     253.05|      20|      20|    1065|    1084|       1
---------------------------------------------------------------------------
  965-  978 (26.51/ 7.42)	HHQN.PIHQ....EAH.....QH..H
  980-  989 (25.04/ 6.56)	HHPQ.........Q.H....QQP..S
  990- 1005 (25.99/ 7.11)	MPPP.Q....LIPQHH.L..QHH..Q
 1009- 1029 (32.41/10.89)	HQQQ.QQHLSQMMPPP....QQPlqH
 1046- 1064 (26.69/ 7.53)	HHQQ..HQMA..MHQQ.MypGQM..F
 1065- 1084 (48.32/20.25)	HHPQ.GGHMGYGMQHH.M..QQP..H
 1086- 1103 (34.21/11.95)	HHPQmQGQMPGQMQHM.M.......H
 1109- 1129 (33.89/11.77)	QQQQ.YAYMMQQQQHHyM..QQQ..H
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     241.66|      78|     347|     372|     501|       3
---------------------------------------------------------------------------
  372-  466 (117.37/98.03)	PITYHCMLAVIfKQLCAKPDedltSEYYQVMEKKSPKDI.VVMGNY...LVDFI..IADVKNNQDVNEQTFKTiakTAALMCFHSNVHRadrfllsliMHP
  505-  588 (124.29/120.33)	KDPYEYIRAIV.KYHDAFPE....FEACEVVPKNDATGTnVHMPTYygcLIERLlpILDQYVYVALEQQGYKM...SNALLQLVSMFYK.........YHP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.21|      36|      62|     813|     849|       4
---------------------------------------------------------------------------
  813-  849 (64.60/54.31)	DLWYTLRLVM..PIIRRfWDSWDFAKTMRALRERFGPLV
  876-  913 (60.61/44.89)	DLFYNCKYVFvgDFLRE.TAITEFAKLPEAMRERLKYYV
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     138.16|      40|     107|      42|      81|       5
---------------------------------------------------------------------------
   42-   81 (70.60/44.30)	RIGAQIVPAMSEALNTPPDPSQPTFD.LSYQRKAVNQFDAF
  147-  187 (67.56/42.05)	HISTQERAADSATNNQAKDQCHFLFDfLAYRLPHVHSYGKY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      82.08|      21|      21|     920|     940|       6
---------------------------------------------------------------------------
  920-  937 (26.70/ 9.46)	......PPETPEREKTPERRDQQK
  938-  960 (32.34/13.09)	EQQeavPNLAPQPNH.PHLLHQQQ
 1031- 1044 (23.04/ 7.11)	PHH...PMDMPPPTSAP.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.29|      38|     125|     613|     658|       7
---------------------------------------------------------------------------
  613-  658 (46.81/48.70)	FVSAFASQiEECHLTEE...FEKYNhqkSSceeLIMELLDRmAASLDFV
  740-  780 (62.48/35.35)	FIGVFKNG.ETANLKFEeivFDNYD...SS...LLLHLPNR.ARSINMI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16236 with Med23 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LKYYVSQNEPAPPETPEREKTPERRDQQKEQQEAVPNLAPQPNHPHLLHQQQPHQQHHQNPIHQEAHQHHPHHPQQHQQPSMPPPQLIPQHHLQHHQQLHHQQQQQHLSQMMPPPQQPLQHLPHHPMDMPPPTSAPMHHQQHQMAMHQQMYPGQMFHHPQGGHMGYGMQHHMQQPHPHHPQMQGQMPGQMQHMMHNMTPQQQQQYAYMMQQQQHHYMQQQHQHQQHHHM
909
1137










Molecular Recognition Features






MoRF SequenceStartStop




1) RLKYYV
908
913