<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16230

Description Uncharacterized protein
SequenceMTLMIDEGFKKKLAVSRERVEDLFYFENSKEIGRGTYGLVYKAVPKHQNGRFPNKEYALKMIEGQGFSMSACREIALFRELRHPNLICLQRVFLTNEKKVWLLLDYAEHDLWHVIKHHRTAKTKKVPIMVPRNMVKNILFQILSGMHYLHSNWVLHRDLKPANILLMGDGGPDMRGRVKIADLGFSRIFANPLKPMAELDPVVVTFWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTAEPLFFCKEEDIKAQNPYHYDQVKRIFHLLGYPSDTDWPDMKKMPDHQRLLNDARNEGTPIQTFPNSLQRYFDKWKINSQSSPYRLLVKLLTVDPLKRVSCEEAMNDIYFRKMERPPRETDDVFNKYPIPYAKKEQQITQQQQQQQQQQQQQQQQQQQQQMQQPQMGPPQMIGQPQMGQPQMGQPQMGQPQMGQPQMGQPQMGQPQMGQPQMVPSQMGQPPMGGPHPGVVAPDGHAHPMMQQQHQSQHHMQYQQMHDSMQGGMDDGGPQAKMMRMSNVPVGRYGPMGPPYGPQDFHAPQGPPMMQMMPQPGSSGYYQQRPGQPPGPGPQGYMNPQMGMPMGMRPQGVPQQAYMPGRGMPPPQGPNPQQQQQWQQYHR
Length615
PositionKinase
OrganismCaenorhabditis nigoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.08
Grand average of hydropathy-0.810
Instability index62.37
Isoelectric point9.30
Molecular weight70784.88
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16230
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     168.24|      19|      19|     412|     430|       1
---------------------------------------------------------------------------
  391-  409 (39.39/ 9.97)	QQQQQQQQMQ.QPQMGPPQM
  412-  430 (47.88/13.84)	QPQMGQPQMG.QPQMGQPQM
  432-  450 (47.88/13.84)	QPQMGQPQMG.QPQMGQPQM
  571-  588 (33.09/ 7.11)	NPQMGMP.MGmRPQ.GVPQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     261.91|      51|      61|     456|     510|       2
---------------------------------------------------------------------------
  350-  390 (49.05/10.39)	................KM...................ER.PPRETDdvfnkY.P....IPYAKKEQQITQQQQQQQQQQQQQ
  456-  492 (68.58/17.54)	.....................................GQ.PPMGGP.....H.P.GVVAPDGHAHPMMQQQHQSQHHMQYQQ
  493-  556 (76.41/26.42)	MHDSMQGGmddgGPQAKM...........mrmsnvpvGRyGPMGPP.....YgPqDFHAPQGP..PMMQMMPQPGSSGYYQQ
  557-  614 (67.87/17.87)	RPGQPPGP....GPQGYMnpqmgmpmgmrpqgvpqqaYM.PGRGMP.......P.....PQG.PNPQQQQQWQQYH......
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16230 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AMNDIYFRKMERPPRETDDVFNKYPIPYAKKEQQITQQQQQQQQQQQQQQQQQQQQQMQQPQMGPPQMIGQPQMGQPQMGQPQMGQPQMGQPQMGQPQMGQPQMGQPQMVPSQMGQPPMGGPHPGVVAPDGHAHPMMQQQHQSQHHMQYQQMHDSMQGGMDDGGPQAKMMRMSNVPVGRYGPMGPPYGPQDFHAPQGPPMMQMMPQPGSSGYYQQRPGQPPGPGPQGYMNPQMGMPMGMRPQGVPQQAYMPGRGMPPPQGPNPQQQQQWQQYHR
342
615










Molecular Recognition Features






MoRF SequenceStartStop




1) QGPNPQQQQQWQQYHR
2) YMPGRGMP
600
590
615
597