<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16219

Description Uncharacterized protein
SequenceMSGQGPPSNLTPQQQHMIMQQQQQQQMMRQQQIQQQQLHQRQLQQQQAQQQQSYQRSRTPQMQQHPGGGSPGSHLQMHPHLQSQGHMQPRSPLVGQHHPAPGSIPPGNPATPQMMQQQMGMNQPMSLPAPHVSRPGSVAPPASVPPNMHTGPSSNQMDQMGGGQPQYSHHLQPQQPLSRPGSQQSHIAGGHGGPHSVQQPGSIQRPGSVLAPGSIQQPGSLLAPGSIQQPGSVLAPGSIQQPGSLLAPGSMHQPGSVQQPGSLGAPLSHTGAGGPQSVQGYGPGSVQPPGSAQAPSSVQPGSTFAPGSLQAPASQQPPASIQPPPSAASGSVAGPASAAPAKVEPLKPNEEQIRMVQDPVDLVRNLVQKDLRMSVVEMNKRGAELLHQKEEGAIKEEDRQQYKRATNDFHAVCDEIDRTLTTIMETAKQITKLDKVFQDRTSKEIDGEAMVNSVQKFVDETGIVQKMFDDTVNSVTSTMEKMRRRQKKWEDQQQQQENAEDMEMAE
Length506
PositionTail
OrganismCaenorhabditis nigoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.02
Grand average of hydropathy-0.882
Instability index74.03
Isoelectric point7.07
Molecular weight54454.27
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16219
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     271.98|      22|      22|     200|     221|       1
---------------------------------------------------------------------------
  101-  127 (33.53/ 8.06)	PGSIP.PGNPATPQMMQQqmgmnqPMSL
  200-  221 (47.87/14.61)	PGSIQRPGSVLAPGSIQQ......PGSL
  224-  245 (47.62/14.50)	PGSIQQPGSVLAPGSIQQ......PGSL
  248-  263 (34.17/ 8.35)	PGSMHQPGSV......QQ......PGSL
  275-  292 (36.94/ 9.62)	PQSVQGYG....PGSVQP......PGSA
  295-  315 (37.76/ 9.99)	PSSVQ.PGSTFAPGSLQA......PASQ
  318-  338 (34.10/ 8.33)	PASIQPPPSA.ASGSVAG......PASA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.06|      22|      26|      13|      36|       2
---------------------------------------------------------------------------
   28-   50 (36.11/10.44)	MRQQQIQQQQLHQRqLQQQQ......AQQ
  157-  184 (36.95/ 8.08)	MDQMGGGQPQYSHH.LQPQQplsrpgSQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.83|      15|      30|      52|      66|       3
---------------------------------------------------------------------------
   52-   66 (31.51/14.37)	QSYQRSRTPQM.QQHP
   84-   99 (26.32/10.65)	QGHMQPRSPLVgQHHP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.02|      19|      19|     452|     470|       4
---------------------------------------------------------------------------
  452-  470 (32.68/22.96)	NSVQKFVDETGIVQKMFDD
  473-  491 (33.34/23.56)	NSVTSTMEKMRRRQKKWED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.13|      15|      21|     380|     399|       8
---------------------------------------------------------------------------
  380-  399 (19.96/23.23)	KRGAELLHqkeegAIKEE.DR
  403-  418 (24.17/14.26)	KRATNDFH.....AVCDEiDR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16219 with Med29 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EMNKRGAELLHQKEEGAIKEEDRQQYKRATNDFHA
2) MSGQGPPSNLTPQQQHMIMQQQQQQQMMRQQQIQQQQLHQRQLQQQQAQQQQSYQRSRTPQMQQHPGGGSPGSHLQMHPHLQSQGHMQPRSPLVGQHHPAPGSIPPGNPATPQMMQQQMGMNQPMSLPAPHVSRPGSVAPPASVPPNMHTGPSSNQMDQMGGGQPQYSHHLQPQQPLSRPGSQQSHIAGGHGGPHSVQQPGSIQRPGSVLAPGSIQQPGSLLAPGSIQQPGSVLAPGSIQQPGSLLAPGSMHQPGSVQQPGSLGAPLSHTGAGGPQSVQGYGPGSVQPPGSAQAPSSVQPGSTFAPGSLQAPASQQPPASIQPPPSAASGSVAGPASAAPAKVEPLKPNEEQIRMVQDPVD
3) SVTSTMEKMRRRQKKWEDQQQQQENAEDMEMAE
377
1
474
411
361
506










Molecular Recognition Features






MoRF SequenceStartStop




1) LTPQQQH
2) SYQRSRTPQMQ
10
53
16
63