<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16218

Description Uncharacterized protein
SequenceMQQHPGGGSPGSHLQMHPHLQSQGHMQPRSPLVGQHHPAPGSIPPGNPATPQMMQQQMGMNQPMSLPAPHVSRPGSVAPPASVPPNMHTGPSSNQMDQMGGGQPQYSHHLQPQQPLSRPGSQQSHIAGGHGGPHSVQQPGSIQRPGSVLAPGSIQQPGSLLAPGSIQQPGSVLAPGSIQQPGSLLAPGSMHQPGSVQQPGSLGAPLSHTGAGGPQSVQGYGPGSVQPPGSAQAPSSVQPGSTFAPGSLQAPASQQPPASIQPPPSAASGSVAGPASAAPAKVEPLKPNEEQIRMVQDPVDLVRNLVQKDLRMSVVEMNKRGAELLHQKEEGAIKEEDRQQYKRATNDFHAVCDEIDRTLTTIMETAKQITKLDKVFQDRTSKEIDGEAMVNSVQKFVDETGIVQKMFDDTVNSVTSTMEKMRRRQKKWEDQQQQQENAEDMEMAE
Length445
PositionTail
OrganismCaenorhabditis nigoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.02
Grand average of hydropathy-0.746
Instability index68.26
Isoelectric point6.41
Molecular weight47088.17
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP16218
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     253.47|      21|      21|     145|     165|       1
---------------------------------------------------------------------------
   45-   70 (29.82/ 7.93)	PGNPATPQMMQQqmgmnqPMSLPAP.H
  145-  165 (45.24/16.11)	PGSVLAPGSIQQ......PGSLLAPGS
  169-  189 (45.24/16.11)	PGSVLAPGSIQQ......PGSLLAPGS
  193-  207 (31.88/ 9.02)	PGSV......QQ......PGSLGAPLS
  220-  236 (34.53/10.43)	YG....PGSVQP......PGSAQAPSS
  239-  259 (37.98/12.26)	PGSTFAPGSLQA......PASQQPPAS
  263-  281 (28.76/ 7.37)	PPSA.ASGSVAG......PAS.AAPAK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     100.87|      21|      21|     373|     393|       3
---------------------------------------------------------------------------
  353-  372 (19.88/ 9.68)	DEI..DRT...LTTImETAKQITKL
  373-  393 (34.72/21.38)	DKVFQDRT...SKEI.DGEAMVNSV
  394-  414 (24.82/13.57)	QK.FVDETgivQKMF.DD..TVNSV
  425-  441 (21.45/10.91)	QKKWEDQQ...QQQE.NAEDM....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.27|      24|      39|      80|     103|       4
---------------------------------------------------------------------------
   83-  107 (44.19/17.39)	VPPNMHTGPSSNQMDQMGG.GQpQYS
  111-  135 (41.08/15.64)	QPQQPLSRPGSQQSHIAGGhGG.PHS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP16218 with Med29 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) EMNKRGAELLHQKEEGAIKEEDRQQYKRATNDFHA
2) MQQHPGGGSPGSHLQMHPHLQSQGHMQPRSPLVGQHHPAPGSIPPGNPATPQMMQQQMGMNQPMSLPAPHVSRPGSVAPPASVPPNMHTGPSSNQMDQMGGGQPQYSHHLQPQQPLSRPGSQQSHIAGGHGGPHSVQQPGSIQRPGSVLAPGSIQQPGSLLAPGSIQQPGSVLAPGSIQQPGSLLAPGSMHQPGSVQQPGSLGAPLSHTGAGGPQSVQGYGPGSVQPPGSAQAPSSVQPGSTFAPGSLQAPASQQPPASIQPPPSAASGSVAGPASAAPAKVEPLKPNEEQIRMVQDPVD
3) SVTSTMEKMRRRQKKWEDQQQQQENAEDMEMAE
316
1
413
350
300
445

Molecular Recognition Features

MoRF SequenceStartStop
1) HLQMH
13
17