<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16191

Description Uncharacterized protein
SequenceMSSQKKRITAMSFPTSSAAEEEDGFPEPGVASWYDAQPGKRLLRRPNYRMGTADVYEQHKNQEEDMLTTERLKKGYQVPVTHYELQSLIFNASENKLLRLDRAPRRTYCMISSVVHRRGEYHMNFDSNRKVAKGEMPRFAKIRFKRILEDRVKFFSALFRGTPLQYLQKKVPYYRRKELLLLEFYDYQIRYDRAIWCVKLVSILGFNCSAKAQKKALLDLATLEWSQACGKVTYYLLLALTKTYKKGPKAFKESVKMWYYLTRFMMYMFQDGVVDKHEFLNDLTETFNVFFIKGSLANAKILELFMEYYIFFLDDLSSSLILARRASCLLCKALGLLSEINEAYIKTQFYKNENKQEFMGHQDVWSIDAQPGVDFKDYIGDHKEFIDPDDFFRFVNDLPDAAYFEDYEDKTAEQVAEEELQTMEAPRRARNYIYSALKSVKDHVDIPIDSDDELYIPSDVESLTTPEPEDPEEGPEEDPSKSVPSPTSSAGPASIEDDCWRTRGLVPQTVAKPAPEPVQQPVPQPPPKNLNIKSEPVDLEYEKNFGNPVKSKNFNINIKAEPMDYDEYSTEPPQPLQPPQTFQQRPETPEKEKAPEQPAEPPRWTLAELPKDFFSKNLEVPAPWTRPREKPIERKRGYNLLCTDRFPVNEDVFEEFKDPDSPDGSRPASPVEPIPFKKLHKTPPKRVLTDADEFGHIPAQKRKINPKLANGKYSETLFVYYLINGGVAFDPKHDGDEMDFSNPTPPEAPPPPPPVDFETSPSASPAPDTDKEDDDGKAKEGGDKAAEKSTDKSAGEKEASEKEKTTDGKKDGDKPAEEKSKKDGKAAEEKKTVDEHLNDLIIPMDVEAEAASKRNSATNSKDDEAEDANKVAGDAPVVEATPAAGTSEKHPEAEVTQVETNDVEMESVDSETNKESTSDPTADKPSNGEEPMEVDDPQKKLPSPSAAAEGDDASKKSKEGEKPDAPAIELVDLEALDDIPLPTDDLMLPDEDEIQVIEKPKHPDADFCEVVEVVEKDKDKTPETAGEGEKGAEKEPEKIPEPIPAVEPVPEPVKTPEKPKTPEPPRLYTAEEIEQLKKDKRRQRMLDKLTDAFKIQMESDKKYEENNIHPSFKVYDQSRSFRRPLHLLSSMVQYLAFRTPESFVWNNLEVPRPDKCHKILPQLCGSPLDYLPCELHELPVMEGNDHHVEHLRLRHHEIVRRSQAADENWLPGGADVLQYGRIIDACVDVIGLMDCINVEKPKSIYNVSQRLFNFREKFAKEEALLRIKLMFKWCISEEREGSFRPVYCARMLEYGLTRSVDGLIGGWQIMDLFFNFMATEGPKPGMANYQAKFDACAGIMIELIRHKLFTVADILRELEKDLDIDYTLPLMARQRKQKMPKISKKEKTPEEPDNTKLIHFTTEHTPKRLFMGRKMDLLERMIIMMPQFGNSKDSDEFKIRSQLLFGLRPSENIYFRRAKTICQGICKEFDSKLYIDFNDKLTHHRKLNQSRLDDLLRQFRAQTYHDQHVILEKIVIHLTENIGRFLEKKNAHLPAPEVVNIICEMYEYSMDITSIFDFFEVLHPYLKAVDEKIAAFDLDLVPDMYHTEIAYIFVSFFMKHYQRFLLHKRNNHITNQLYFGIRKMIMDKKRFMTCWGRVIAIFVNHIRPVLIGGGFQIISLEGKEWEFARAHPNKRAFNLECSYNEDFAASQLSSKILRYDSFTDMKWILDNLEGTVKRKNSKPPKPNRYSFVINAFMEARKYGQNFDRINELANYCANVTANDPPLSEYWIGAIRGLCCLSMDIRDPRDPLSLFKEMGRNIDISDCSTHYSLSTFITCLAGKAAFYIPRLLHELTKNVFKLMLHNDGRLTSKQTRDVKRKSANKTTETRTLSEAEPGVCLSLLIIAGLCCPGDEPFGLSVHYRGIEKKKKRFSETADERIMHMFHWLEMDKSMFRTLASISELLEALQSRYRDANLVLPQSFQLKHQIVDPNKPPPHEKAPYRPQFLFNIAKAVFFTICEQDWVTIRMYQFVRIKQMEPFNQEKLKKNCLGQQLLRISLRRKTERSNVHSLFEAHKISKKATVDKVLSFMNLWNFRATLFDLMLMIKEISPDGNTKHAQQGAIAADALMSEIGKCCRDMFLAAYKADAKMPNVKKLMDFRFGDISKYWLLAPLVRMCPKPINIPPQYANTHVQTVASKFLKEASALMDTPPTTTPKERLLQCSWAMSKLPFINMILTCLACEKTQNGKDTFLNSVYQQLQREVFRDHNKRSKWTNRPEHRDCTVLRVNLIAYMYKEILKPTHVEVWGLLLYQLMFHGIINPSRERYVFENCYDMLQHMVLWTLVNGDNMNSHDRYGSIRVRWPNYAGLMKKIRKEIQDRHVHPSRTCLLRFLPIGKLQTSTISYKKYHKRTIRPSAVKSKKFMSNEGIRSGKYVYLPEEKVKTNAYDHMKNVPDGIQKGGWKFRMFQTTRLDKVGKSVLHQLRAKIPHTHIGEFKRPCNIMLDNMSEDFYLRPPEVEITKTVEPVADDEETTVVKKPEEESAEKKKDEAKKADEKTTKADDEKKNDETADAKKDNEKQKEEKDKPEDSAKAKTDDVTAKDTEKDTSAPTDAAKAAAAPVAAAPDANKEMDTSTPKPAPVTRETSTTRGRGGGRKRNSGGRATGGSRAKRTNSRANANAETAAAAETSATTKAGASGGGSSNYHAAMRANQPPMSNGSSDETKANIRNLLNRKQEKRNSLADANAAAAVAAAAAAAAAASGNIAPALAPIVQPGIPAAGATTQQQPHPGMQHQGMGSGMGAGMGGMNPTMHAPPPYSSSSMNPFANQPHFAAPNPGPITTMAHRSAAAVTPEERARIMEEQMHQKLAQQQQLIEQQNRQREAREREAREHQERLAREAKIREEQMQLERQRVIEENNRKMEEQRIQREKEEAARRLEEQRRRDEEARLAYQIEQDRIRKEQERQARLEAERLKREAEEREMRERERQRLEQERLQREMEEKARREKEEQARIERERLERERVAREALAAQQAQQAQQQRQRALMEQQQRQQMMNQQQQQQAPYGQQQPQGQPPSYQQSSYQNPSGYQQGQQSGQNQPPNYQQTSHTNPAMQNPSMQQAQQPPAYQQDNSQMNMQQNRQQQYGNQSQQSQQAQQGQYPQQYPQQLNQNQQMNQQQQQRNPFGAQPEMQIGGPKMLMQAKPDEAHAQQYQHTQAQLALSQKEKEMQYLKAKNLQAGQAAGQQQPRFGENPQQNVPGFNRNLPYPQQQQQSQQPGTSQIPNTTPTRPTNPMQGQQQQGGMQNYQNQPVLGQPGPMQTGGQAGQQQQQNQFQRQGMHTTPTKNEMAMRQGQMGGQMGQQGQMGQQQGQMGQQMQNRPAQGGFNQQNQGFQQQGGQQSAQGSFNNQPQNQFAGQQQQMGQNQGQTLQQGQNQFGRQAASNQEAGFQQQPGFNQNPGQNYQRPEQQQQQNQNQWNQQNQQMRPQQPQQPSQQQQNVPFGRNEQQQQFQQSQHQQQNKPAMGQQGFNYQGQQQQGQGFDQSSQQAQQHQNPTHHQQGHMQQQNPQQQQYNQTQQSSQQQQQGNQFPGFSGSSNQARSSNILSQSMEDAGLNQGFQSGNASNQQASSSNQQGNYGMQQGQQNPMQGQMHHQQGQQNQNQQQRSGMGQQGMGQQGGMGQPGMGSQSAMGQHQHGMGRSTMGQPGMQQSGMQQQHGMQQGAQQPAMQQSGMQQHGMSQSGMGQPGMGGMQQQNRNSFGSMGQQGQQSGQQSQQHQQMPQQNQQAQQRQMPGGGVQLPPYSMGQQQQTQQQQPNQQQMDQLRRQQQMQQMARQQAMQQQQGVQQGQPQMQGYGNQGQQQQQFPQMQQHRGQGQGMGGAGQQHQQVPQQQQNQYFQPQQQQDQRMQQQPGGQQQQGHSGQQQNNQYYNPNQQQY
Length3901
PositionKinase
OrganismCaenorhabditis nigoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.07
Grand average of hydropathy-0.990
Instability index56.17
Isoelectric point8.07
Molecular weight445656.68
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16191
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            18|    1175.98|      60|      60|    3636|    3695|       1
---------------------------------------------------------------------------
 2753- 2807 (61.72/17.71)	GIPA....A...G.attQQ....QPH...............PGM............Q..HQG.MG..SG.......M....G......AG...MGGmNPTMH.A.PPPYSSSSMNpfanQ.P
 3009- 3041 (37.07/ 7.28)	..................Q....QAQQA....Q.QQ.R..QRAL............ME.QQQ.RQQM.........M....N....Q.QQ...QQQ.AP.......................
 3068- 3115 (62.08/17.87)	G.QQ....S...G....QN....QPPNY....Q.QTSH.tNPAM.........................................qN.PS...MQQ.AQQPP.AYQQDNSQMNMQ....Q.N
 3116- 3163 (69.58/21.04)	RQQQ....Y...G....NQ....SQQSQ....Q.........................aQQG.QYPQQY.......P....Q....Q.LN...QNQ.Q..MN.QQQQ..QRNPFG...aQ.P
 3164- 3241 (48.02/11.92)	EMQI....G...GpkmlMQakpdEAHAQ....QyQHTQ.aQLALsqkekemqylkaKN.LQA..GQAAG.......Q....Q....Q.PR...FGE.NPQ...QNVPGFNRN.LP....Y.P
 3242- 3297 (52.16/13.67)	..QQ....Q.........................QQSQ..QPGTsqipnttptrptNP.MQG.QQQQGG.......MqnyqN....Q.PV...LGQ.P...G.PMQTG......G....Q.A
 3298- 3352 (72.77/22.39)	GQQQ....Q...Q....NQ...fQRQGM....H.TTPT..KNEM......amrqgqMG.GQ..MGQQGQ.......M....G....Q........Q.QGQMG.QQMQ.......N....R.P
 3353- 3398 (61.64/17.68)	A..Q....G...G....FN....QQN........QGFQ..Q...................QG..GQQSA.......Q....GsfnnQ.PQnqfAGQ.QQQMG.QNQ........G....Q..
 3399- 3443 (57.97/16.13)	TLQQ....G.........Q....NQFGR....Q.AASN..QEA..................G.FQQQPG.......F....N....QnPG...QNY.QRPEQ.QQQQ.....N.........
 3444- 3478 (49.09/12.37)	..QN....Q...W....NQ....QNQQM....RpQQPQ..QP.....................................................S.QQ....QQNVPFGRNEQ.....Q.Q
 3479- 3508 (55.06/14.89)	QFQQ....S...Q....HQ....QQN..............KPA.............MG.QQG.FNYQ..................................G.QQQQG...........Q..
 3509- 3558 (70.05/21.23)	GFDQ....S...S....QQ...aQQHQ.............NPTH............H..QQGhMQQQNP.......Q....Q....Q.QY...NQT.QQSSQ.QQQQG......N....QfP
 3559- 3605 (52.69/13.89)	GF......S...G....SS....NQ...........AR..SSNI............LS..QS.M.EDAG.......L....N....Q.......GF.QSGNA.SNQQASSSNQQG....N.Y
 3606- 3673 (103.94/35.57)	GMQQ....GqqnP....MQ....GQMHH....Q.QGQQ..NQNQ.......qqrsgMG.QQG.MGQQGG.......M....G....Q.PG...MGS.QSAMG.QHQHGMGRSTMG....Q.P
 3674- 3732 (100.33/34.04)	GMQQ....S...G....MQ....QQHGM....Q.QGAQ..QPAM........qqsgMQ.QHG.MS.QSG.......M....G....Q.PG...MG......GmQQQNRNSFGSMG....Q.Q
 3733- 3793 (74.54/23.13)	G.QQ....S...G....QQ...sQQHQQmpqqN.QQAQ..QRQM............PG.........GGvqlppysM....G....Q.QQ...QTQ.QQQPN.QQQMDQLRR.......Q.Q
 3794- 3848 (73.96/22.89)	QMQQmarqQ...A....MQ....QQQGV....Q.QG....QPQM..........qgYG.NQG.QQQQ...................QfPQ...M...QQHRG.QGQ.GMGGA..G....Q..
 3849- 3896 (73.30/22.61)	..QH...................QQVPQ....Q.QQNQyfQPQQ............QQ.DQR.MQQQPG............G....Q.QQ...QGH.S...G.QQQN....NQYY....N.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     145.27|      21|      21|    2938|    2958|       2
---------------------------------------------------------------------------
 2854- 2874 (32.08/17.19)	QQNRQR...EAREREAREHQERLA
 2906- 2928 (23.33/ 9.93)	REKEEAarrLEEQRR.RDEEARLA
 2930- 2952 (27.46/13.35)	QIEQDR.irKEQERQARLEAERLK
 2953- 2974 (33.08/18.01)	REAEER.emRERERQ.RLEQERLQ
 2975- 2997 (29.33/14.90)	REMEEK.arREKEEQARIERERLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      93.44|      17|      17|    2516|    2532|       3
---------------------------------------------------------------------------
 2500- 2513 (18.10/ 7.67)	KTVEPVAD...DEETTV
 2516- 2532 (27.25/16.15)	KPEEESAEKKKDEAKKA
 2535- 2551 (24.98/14.05)	KTTKADDEKKNDETADA
 2579- 2595 (23.11/12.31)	KDTEKDTSAPTDAAKAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.33|      40|      42|    2622|    2662|       4
---------------------------------------------------------------------------
 2622- 2661 (72.52/46.13)	ETS.TTR.GRGGGRKRN..SGGRA......TGGS.............RAKRTNSRANANAETA
 2665- 2727 (40.81/18.31)	ETSaTTKaGASGGGSSNyhAAMRAnqppmsNGSSdetkanirnllnrKQEKRNSLADANAAAA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16191 with Med12 domain of Kingdom Metazoa
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