<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16190

Description Uncharacterized protein
SequenceMSFPTSSAAEEEDGFPEPGVASWYDAQPGKRLLRRPNYRMGTADVYEQHKNQEEDMLTTERLKKGYQVPVTHYELQSLIFNASENKLLRLDRAPRRTYCMISSVVHRRGEYHMNFDSNRKVAKGEMPRFAKIRFKRILEDRVKFFSALFRGTPLQYLQKKVPYYRRKELLLLEFYDYQIRYDRAIWCVKLVSILGFNCSAKAQKKALLDLATLEWSQACGKVTYYLLLALTKTYKKGPKAFKESVKMWYYLTRFMMYMFQDGVVDKHEFLNDLTETFNVFFIKGSLANAKILELFMEYYIFFLDDLSSSLILARRASCLLCKALGLLSEINEAYIKTQFYKNENKQEFMGHQDVWSIDAQPGVDFKDYIGDHKEFIDPDDFFRFVNDLPDAAYFEDYEDKTAEQVAEEELQTMEAPRRARNYIYSALKSVKDHVDIPIDSDDELYIPSDVESLTTPEPEDPEEGPEEDPSKSVPSPTSSAGPASIEDDCWRTRGLVPQTVAKPAPEPVQQPVPQPPPKNLNIKSEPVDLEYEKNFGNPVKSKNFNINIKAEPMDYDEYSTEPPQPLQPPQTFQQRPETPEKEKAPEQPAEPPRWTLAELPKDFFSKNLEVPAPWTRPREKPIERKRGYNLLCTDRFPVNEDVFEEFKDPDSPDGSRPASPVEPIPFKKLHKTPPKRVLTDADEFGHIPAQKRKINPKLANGKYSETLFVYYLINGGVAFDPKHDGDEMDFSNPTPPEAPPPPPPVDFETSPSASPAPDTDKEDDDGKAKEGGDKAAEKSTDKSAGEKEASEKEKTTDGKKDGDKPAEEKSKKDGKAAEEKKTVDEHLNDLIIPMDVEAEAASKRNSATNSKDDEAEDANKVAGDAPVVEATPAAGTSEKHPEAEVTQVETNDVEMESVDSETNKESTSDPTADKPSNGEEPMEVDDPQKKLPSPSAAAEGDDASKKSKEGEKPDAPAIELVDLEALDDIPLPTDDLMLPDEDEIQVIEKPKHPDADFCEVVEVVEKDKDKTPETAGEGEKGAEKEPEKIPEPIPAVEPVPEPVKTPEKPKTPEPPRLYTAEEIEQLKKDKRRQRMLDKLTDAFKIQMESDKKYEENNIHPSFKVYDQSRSFRRPLHLLSSMVQYLAFRTPESFVWNNLEVPRPDKCHKILPQLCGSPLDYLPCELHELPVMEGNDHHVEHLRLRHHEIVRRSQAADENWLPGGADVLQYGRIIDACVDVIGLMDCINVEKPKSIYNVSQRLFNFREKFAKEEALLRIKLMFKWCISEEREGSFRPVYCARMLEYGLTRSVDGLIGGWQIMDLFFNFMATEGPKPGMANYQAKFDACAGIMIELIRHKLFTVADILRELEKDLDIDYTLPLMARQRKQKMPKISKKEKTPEEPDNTKLIHFTTEHTPKRLFMGRKMDLLERMIIMMPQFGNSKDSDEFKIRSQLLFGLRPSENIYFRRAKTICQGICKEFDSKLYIDFNDKLTHHRKLNQSRLDDLLRQFRAQTYHDQHVILEKIVIHLTENIGRFLEKKNAHLPAPEVVNIICEMYEYSMDITSIFDFFEVLHPYLKAVDEKIAAFDLDLVPDMYHTEIAYIFVSFFMKHYQRFLLHKRNNHITNQLYFGIRKMIMDKKRFMTCWGRVIAIFVNHIRPVLIGGGFQIISLEGKEWEFARAHPNKRAFNLECSYNEDFAASQLSSKILRYDSFTDMKWILDNLEGTVKRKNSKPPKPNRYSFVINAFMEARKYGQNFDRINELANYCANVTANDPPLSEYWIGAIRGLCCLSMDIRDPRDPLSLFKEMGRNIDISDCSTHYSLSTFITCLAGKAAFYIPRLLHELTKNVFKLMLHNDGRLTSKQTRDVKRKSANKTTETRTLSEAEPGVCLSLLIIAGLCCPGDEPFGLSVHYRGIEKKKKRFSETADERIMHMFHWLEMDKSMFRTLASISELLEALQSRYRDANLVLPQSFQLKHQIVDPNKPPPHEKAPYRPQFLFNIAKAVFFTICEQDWVTIRMYQFVRIKQMEPFNQEKLKKNCLGQQLLRISLRRKTERSNVHSLFEAHKISKKATVDKVLSFMNLWNFRATLFDLMLMIKEISPDGNTKHAQQGAIAADALMSEIGKCCRDMFLAAYKADAKMPNVKKLMDFRFGDISKYWLLAPLVRMCPKPINIPPQYANTHVQTVASKFLKEASALMDTPPTTTPKERLLQCSWAMSKLPFINMILTCLACEKTQNGKDTFLNSVYQQLQREVFRDHNKRSKWTNRPEHRDCTVLRVNLIAYMYKEILKPTHVEVWGLLLYQLMFHGIINPSRERYVFENCYDMLQHMVLWTLVNGDNMNSHDRYGSIRVRWPNYAGLMKKIRKEIQDRHVHPSRTCLLRFLPIGKLQTSTISYKKYHKRTIRPSAVKSKKFMSNEGIRSGKYVYLPEEKVKTNAYDHMKNVPDGIQKGGWKFRMFQTTRLDKVGKSVLHQLRAKIPHTHIGEFKRPCNIMLDNMSEDFYLRPPEVEITKTVEPVADDEETTVVKKPEEESAEKKKDEAKKADEKTTKADDEKKNDETADAKKDNEKQKEEKDKPEDSAKAKTDDVTAKDTEKDTSAPTDAAKAAAAPVAAAPDANKEMDTSTPKPAPVTRETSTTRGRGGGRKRNSGGRATGGSRAKRTNSRANANAETAAAAETSATTKAGASGGGSSNYHAAMRANQPPMSNGSSDETKANIRNLLNRKQEKRNSLADANAAAAVAAAAAAAAAASGNIAPALAPIVQPGIPAAGATTQQQPHPGMQHQGMGSGMGAGMGGMNPTMHAPPPYSSSSMNPFANQPHFAAPNPGPITTMAHRSAAAVTPEERARIMEEQMHQKLAQQQQLIEQQNRQREAREREAREHQERLAREAKIREEQMQLERQRVIEENNRKMEEQRIQREKEEAARRLEEQRRRDEEARLAYQIEQDRIRKEQERQARLEAERLKREAEEREMRERERQRLEQERLQREMEEKARREKEEQARIERERLERERVAREALAAQQAQQAQQQRQRALMEQQQRQQMMNQQQQQQAPYGQQQPQGQPPSYQQSSYQNPSGYQQGQQSGQNQPPNYQQTSHTNPAMQNPSMQQAQQPPAYQQDNSQMNMQQNRQQQYGNQSQQSQQAQQGQYPQQYPQQLNQNQQMNQQQQQRNPFGAQPEMQIGGPKMLMQAKPDEAHAQQYQHTQAQLALSQKEKEMQYLKAKNLQAGQAAGQQQPRFGENPQQNVPGFNRNLPYPQQQQQSQQPGTSQIPNTTPTRPTNPMQGQQQQGGMQNYQNQPVLGQPGPMQTGGQAGQQQQQNQFQRQGMHTTPTKNEMAMRQGQMGGQMGQQGQMGQQQGQMGQQMQNRPAQGGFNQQNQGFQQQGGQQSAQGSFNNQPQNQFAGQQQQMGQNQGQTLQQGQNQFGRQAASNQEAGFQQQPGFNQNPGQNYQRPEQQQQQNQNQWNQQNQQMRPQQPQQPSQQQQNVPFGRNEQQQQFQQSQHQQQNKPAMGQQGFNYQGQQQQGQGFDQSSQQAQQHQNPTHHQQGHMQQQNPQQQQYNQTQQSSQQQQQGNQFPGFSGSSNQARSSNILSQSMEDAGLNQGFQSGNASNQQASSSNQQGNYGMQQGQQNPMQGQMHHQQGQQNQNQQQRSGMGQQGMGQQGGMGQPGMGSQSAMGQHQHGMGRSTMGQPGMQQSGMQQQHGMQQGAQQPAMQQSGMQQHGMSQSGMGQPGMGGMQQQNRNSFGSMGQQGQQSGQQSQQHQQMPQQNQQAQQRQMPGGGVQLPPYSMGQQQQTQQQQPNQQQMDQLRRQQQMQQMARQQAMQQQQGVQQGQPQMQGYGNQGQQQQQFPQMQQHRGQGQGMGGAGQQHQQVPQQQQNQYFQPQQQQDQRMQQQPGGQQQQGHSGQQQNNQYYNPNQQQY
Length3891
PositionKinase
OrganismCaenorhabditis nigoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.07
Grand average of hydropathy-0.990
Instability index56.00
Isoelectric point7.91
Molecular weight444525.33
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16190
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            17|    1138.91|      60|      60|    3626|    3685|       1
---------------------------------------------------------------------------
 2743- 2797 (61.72/14.44)	GIPA....A...G.attQQ....QPH...............PGM............Q..HQG.MG..SG.......M....G......AG...MGGmNPTMH.A.PPPYSSSSMNpfanQ.P
 3058- 3105 (62.08/14.57)	G.QQ....S...G....QN....QPPNY....Q.QTSH.tNPAM.........................................qN.PS...MQQ.AQQPP.AYQQDNSQMNMQ....Q.N
 3106- 3153 (69.58/17.21)	RQQQ....Y...G....NQ....SQQSQ....Q.........................aQQG.QYPQQY.......P....Q....Q.LN...QNQ.Q..MN.QQQQ..QRNPFG...aQ.P
 3154- 3231 (48.02/ 9.63)	EMQI....G...GpkmlMQakpdEAHAQ....QyQHTQ.aQLALsqkekemqylkaKN.LQA..GQAAG.......Q....Q....Q.PR...FGE.NPQ...QNVPGFNRN.LP....Y.P
 3232- 3287 (52.16/11.08)	..QQ....Q.........................QQSQ..QPGTsqipnttptrptNP.MQG.QQQQGG.......MqnyqN....Q.PV...LGQ.P...G.PMQTG......G....Q.A
 3288- 3342 (72.77/18.33)	GQQQ....Q...Q....NQ...fQRQGM....H.TTPT..KNEM......amrqgqMG.GQ..MGQQGQ.......M....G....Q........Q.QGQMG.QQMQ.......N....R.P
 3343- 3388 (61.64/14.42)	A..Q....G...G....FN....QQN........QGFQ..Q...................QG..GQQSA.......Q....GsfnnQ.PQnqfAGQ.QQQMG.QNQ........G....Q..
 3389- 3433 (57.97/13.13)	TLQQ....G.........Q....NQFGR....Q.AASN..QEA..................G.FQQQPG.......F....N....QnPG...QNY.QRPEQ.QQQQ.....N.........
 3434- 3468 (49.09/10.00)	..QN....Q...W....NQ....QNQQM....RpQQPQ..QP.....................................................S.QQ....QQNVPFGRNEQ.....Q.Q
 3469- 3498 (55.06/12.10)	QFQQ....S...Q....HQ....QQN..............KPA.............MG.QQG.FNYQ..................................G.QQQQG...........Q..
 3499- 3548 (70.05/17.37)	GFDQ....S...S....QQ...aQQHQ.............NPTH............H..QQGhMQQQNP.......Q....Q....Q.QY...NQT.QQSSQ.QQQQG......N....QfP
 3549- 3595 (52.69/11.27)	GF......S...G....SS....NQ...........AR..SSNI............LS..QS.M.EDAG.......L....N....Q.......GF.QSGNA.SNQQASSSNQQG....N.Y
 3596- 3663 (103.94/29.29)	GMQQ....GqqnP....MQ....GQMHH....Q.QGQQ..NQNQ.......qqrsgMG.QQG.MGQQGG.......M....G....Q.PG...MGS.QSAMG.QHQHGMGRSTMG....Q.P
 3664- 3722 (100.33/28.02)	GMQQ....S...G....MQ....QQHGM....Q.QGAQ..QPAM........qqsgMQ.QHG.MS.QSG.......M....G....Q.PG...MG......GmQQQNRNSFGSMG....Q.Q
 3723- 3783 (74.54/18.95)	G.QQ....S...G....QQ...sQQHQQmpqqN.QQAQ..QRQM............PG.........GGvqlppysM....G....Q.QQ...QTQ.QQQPN.QQQMDQLRR.......Q.Q
 3784- 3838 (73.96/18.75)	QMQQmarqQ...A....MQ....QQQGV....Q.QG....QPQM..........qgYG.NQG.QQQQ...................QfPQ...M...QQHRG.QGQ.GMGGA..G....Q..
 3839- 3886 (73.30/18.52)	..QH...................QQVPQ....Q.QQNQyfQPQQ............QQ.DQR.MQQQPG............G....Q.QQ...QGH.S...G.QQQN....NQYY....N.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     118.43|      20|      20|    2928|    2947|       2
---------------------------------------------------------------------------
 2856- 2873 (22.86/ 7.47)	AREHQERLAREAKI.....rEE...Q
 2934- 2956 (28.71/11.51)	ARLEAERLKREAEE...remRERERQ
 2957- 2978 (22.58/ 7.28)	.RLEQERLQREMEE...karREKEEQ
 2979- 3003 (22.61/ 7.30)	ARIERERLERERVA.realaAQQAQQ
 3004- 3029 (21.68/ 6.66)	AQQQRQRALMEQQQrqqmmnQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      65.45|      16|      19|    2518|    2533|       3
---------------------------------------------------------------------------
 2518- 2533 (26.94/15.07)	EAK.KADEKTTKADDEK
 2540- 2552 (19.76/ 8.71)	DAK.KDNEK...QKEEK
 2558- 2573 (18.75/ 7.80)	SAKaKTDDVTAK.DTEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.33|      40|      42|    2612|    2652|       4
---------------------------------------------------------------------------
 2612- 2651 (72.52/44.90)	ETS.TTR.GRGGGRKRN..SGGRA......TGGS.............RAKRTNSRANANAETA
 2655- 2717 (40.81/17.81)	ETSaTTKaGASGGGSSNyhAAMRAnqppmsNGSSdetkanirnllnrKQEKRNSLADANAAAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     131.51|      34|      61|    2821|    2854|       5
---------------------------------------------------------------------------
 2821- 2854 (62.54/31.17)	EERARIMEEQMHQ....KLAQQQQLIEQQNR....QREARER
 2874- 2898 (22.73/ 6.39)	..........MQ......L.ERQRVIEENNRkmeeQRIQREK
 2899- 2932 (46.24/21.02)	EEAARRLEEQRRRdeeaRLAYQ...IE.QDR....IRKEQER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.87|      32|      42|    2361|    2402|       7
---------------------------------------------------------------------------
 2361- 2392 (53.88/45.09)	FLPIGKLQTSTISYKKYHKRTIRPSAVKSKKF
 2405- 2436 (58.99/29.30)	YLPEEKVKTNAYDHMKNVPDGIQKGGWKFRMF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.58|      16|      18|    2574|    2589|       8
---------------------------------------------------------------------------
 2574- 2589 (25.88/15.04)	DTSAPTDAAKAAAAPV
 2594- 2609 (28.70/17.65)	DANKEMDTSTPKPAPV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16190 with Med12 domain of Kingdom Metazoa
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