<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16189

Description Uncharacterized protein
SequenceMSSQKKRITAMSFPTSSAAEEEDGFPEPGVASWYDAQPGKRLLRRPNYRMGTADVYEQHKNQEEDMLTTERLKKGYQVPVTHYELQSLIFNASENKLLRLDRAPRRTYCMISSVVHRRGEYHMNFDSNRKVAKGEMPRFAKIRFKRILEDRVKFFSALFRGTPLQYLQKKVPYYRRKELLLLEFYDYQIRYDRAIWCVKLVSILGFNCSAKAQKKALLDLATLEWSQACGKVTYYLLLALTKTYKKGPKAFKESVKMWYYLTRFMMYMFQDGVVDKHEFLNDLTETFNVFFIKGSLANAKILELFMEYYIFFLDDLSSSLILARRASCLLCKALGLLSEINEAYIKTQFYKNENKQEFMGHQDVWSIDAQPGVDFKDYIGDHKEFIDPDDFFRFVNDLPDAAYFEDYEDKTAEQVAEEELQTMEAPRRARNYIYSALKSVKDHVDIPIDSDDELYIPSDVESLTTPEPEDPEEGPEEDPSKSVPSPTSSAGPASIEDDCWRTRGLVPQTVAKPAPEPVQQPVPQPPPKNLNIKSEPVDLEYEKNFGNPVKSKNFNINIKAEPMDYDEYSTEPPQPLQPPQTFQQRPETPEKEKAPEQPAEPPRWTLAELPKDFFSKNLEVPAPWTRPREKPIERKRGYNLLCTDRFPVNEDVFEEFKDPDSPDGSRPASPVEPIPFKKLHKTPPKRVLTDADEFGHIPAQKRKINPKLANGKYSETLFVYYLINGGVAFDPKHDGDEMDFSNPTPPEAPPPPPPVDFETSPSASPAPDTDKEDDDGKAKEGGDKAAEKSTDKSAGEKEASEKEKTTDGKKDGDKPAEEKSKKDGKAAEEKKTVDEHLNDLIIPMDVEAEAASKRNSATNSKDDEAEDANKVAGDAPVVEATPAAGTSEKHPEAEVTQVETNDVEMESVDSETNKESTSDPTADKPSNGEEPMEVDDPQKKLPSPSAAAEGDDASKKSKEGEKPDAPAIELVDLEALDDIPLPTDDLMLPDEDEIQVIEKPKHPDADFCEVVEVVEKDKDKTPETAGEGEKGAEKEPEKIPEPIPAVEPVPEPVKTPEKPKTPEPPRLYTAEEIEQLKKDKRRQRMLDKLTDAFKIQMESDKKYEENNIHPSFKVYDQSRSFRRPLHLLSSMVQYLAFRTPESFVWNNLEVPRPDKCHKILPQLCGSPLDYLPCELHELPVMEGNDHHVEHLRLRHHEIVRRSQAADENWLPGGADVLQYGRIIDACVDVIGLMDCINVEKPKSIYNVSQRLFNFREKFAKEEALLRIKLMFKWCISEEREGSFRPVYCARMLEYGLTRSVDGLIGGWQIMDLFFNFMATEGPKPGMANYQAKFDACAGIMIELIRHKLFTVADILRELEKDLDIDYTLPLMARQRKQKMPKISKKEKTPEEPDNTKLIHFTTEHTPKRLFMGRKMDLLERMIIMMPQFGNSKDSDEFKIRSQLLFGLRPSENIYFRRAKTICQGICKEFDSKLYIDFNDKLTHHRKLNQSRLDDLLRQFRAQTYHDQHVILEKIVIHLTENIGRFLEKKNAHLPAPEVVNIICEMYEYSMDITSIFDFFEVLHPYLKAVDEKIAAFDLDLVPDMYHTEIAYIFVSFFMKHYQRFLLHKRNNHITNQLYFGIRKMIMDKKRFMTCWGRVIAIFVNHIRPVLIGGGFQIISLEGKEWEFARAHPNKRAFNLECSYNEDFAASQLSSKILRYDSFTDMKWILDNLEGTVKRKNSKPPKPNRYSFVINAFMEARKYGQNFDRINELANYCANVTANDPPLSEYWIGAIRGLCCLSMDIRDPRDPLSLFKEMGRNIDISDCSTHYSLSTFITCLAGKAAFYIPRLLHELTKNVFKLMLHNDGRLTSKQTRDVKRKSANKTTETRTLSEAEPGVCLSLLIIAGLCCPGDEPFGLSVHYRGIEKKKKRFSETADERIMHMFHWLEMDKSMFRTLASISELLEALQSRYRDANLVLPQSFQLKHQIVDPNKPPPHEKAPYRPQFLFNIAKAVFFTICEQDWVTIRMYQFVRIKQMEPFNQEKLKKNCLGQQLLRISLRRKTERSNVHSLFEAHKISKKATVDKVLSFMNLWNFRATLFDLMLMIKEISPDGNTKHAQQGAIAADALMSEIGKCCRDMFLAAYKADAKMPNVKKLMDFRFGDISKYWLLAPLVRMCPKPINIPPQYANTHVQTVASKFLKEASALMDTPPTTTPKERLLQCSWAMSKLPFINMILTCLACEKTQNGKDTFLNSVYQQLQREVFRDHNKRSKWTNRPEHRDCTVLRVNLIAYMYKEILKPTHVEVWGLLLYQLMFHGIINPSRERYVFENCYDMLQHMVLWTLVNGDNMNSHDRYGSIRVRWPNYAGLMKKIRKEIQDRHVHPSRTCLLRFLPIGKLQTSTISYKKYHKRTIRPSAVKSKKFMSNEGIRSGKYVYLPEEKVKTNAYDHMKNVPDGIQKGGWKFRMFQTTRLDKVGKSVLHQLRAKIPHTHIGEFKRPCNIMLDNMSEDFYLRPPEVEITKTVEPVADDEETTVVKKPEEESAEKKKDEAKKADEKTTKADDEKKNDETADAKKDNEKQKEEKDKPEDSAKAKTDDVTAKDTEKDTSAPTDAAKAAAAPVAAAPDANKEMDTSTPKPAPVTRETSTTRGRGGGRKRNSGGRATGGSRAKRTNSRANANAETAAAAETSATTKAGASGGGSSNYHAAMRANQPPMSNGSSDETKANIRNLLNRKQEKRNSLADANAAAAVAAAAAAAAAASGNIAPALAPIVQPGIPAAGATTQQQPHPGMQHQGMGSGMGAGMGGMNPTMHAPPPYSSSSMNPFANQPHFAAPNPGPITTMAHRSAAAVTPEERARIMEEQMHQKLAQQQQLIEQQNRQREAREREAREHQERLAREAKIREEQMQLERQRVIEENNRKMEEQRIQREKEEAARRLEEQRRRDEEARLAYQIEQDRIRKEQERQARLEAERLKREAEEREMRERERQRLEQERLQREMEEKARREKEEQARIERERLERERVAREALAAQQAQQAQQQRQRALMEQQQRQQMMNQQQQQQAPYGQQQPQGQPPSYQQSSYQNPSGYQQGQQSGQNQPPNYQQTSHTNPAMQNPSMQQAQQPPAYQQDNSQMNMQQNRQQQYGNQSQQSQQAQQGQYPQQYPQQLNQNQQMNQQQQQRNPFGAQPEMQIGGPKMLMQAKPDEAHAQQYQHTQAQLALSQKEKEMQYLKAKNLQAGQAAGQQQPRFGENPQQNVPGFNRNLPYPQQQQQSQQPGKPKVFQNRGLQRLIVKILGTSQIPNTTPTRPTNPMQGQQQQGGMQNYQNQPVLGQPGPMQTGGQAGQQQQQNQFQRQGMHTTPTKNEMAMRQGQMGGQMGQQGQMGQQQGQMGQQMQNRPAQGGFNQQNQGFQQQGGQQSAQGSFNNQPQNQFAGQQQQMGQNQGQTLQQGQNQFGRQAASNQEAGFQQQPGFNQNPGQNYQRPEQQQQQNQNQWNQQNQQMRPQQPQQPSQQQQNVPFGRNEQQQQFQQSQHQQQNKPAMGQQGFNYQGQQQQGQGFDQSSQQAQQHQNPTHHQQGHMQQQNPQQQQYNQTQQSSQQQQQGNQFPGFSGSSNQARSSNILSQSMEDAGLNQGFQSGNASNQQASSSNQQGNYGMQQGQQNPMQGQMHHQQGQQNQNQQQRSGMGQQGMGQQGGMGQPGMGSQSAMGQHQHGMGRSTMGQPGMQQSGMQQQHGMQQGAQQPAMQQSGMQQHGMSQSGMGQPGMGGMQQQNRNSFGSMGQQGQQSGQQSQQHQQMPQQNQQAQQRQMPGGGVQLPPYSMGQQQQTQQQQPNQQQMDQLRRQQQMQQMARQQAMQQQQGVQQGQPQMQGYGNQGQQQQQFPQMQQHRGQGQGMGGAGQQHQQVPQQQQNQYFQPQQQQDQRMQQQPGGQQQQGHSGQQQNNQYYNPNQQQY
Length3920
PositionKinase
OrganismCaenorhabditis nigoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.07
Grand average of hydropathy-0.986
Instability index55.95
Isoelectric point8.27
Molecular weight447846.37
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16189
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     263.55|      21|      21|    3692|    3712|       1
---------------------------------------------------------------------------
 3350- 3370 (33.30/ 7.83)	MGQQGQMG..QQQ.G.QMGQQM.....QNR
 3371- 3391 (30.54/ 6.52)	PAQGGFNQ..QNQ.G.FQQQGG.....QQS
 3467- 3486 (37.25/ 9.72)	NQQNQQMR...PQ.Q.PQQPSQ.....QQQ
 3632- 3652 (33.59/ 7.97)	NPMQGQMH..HQQ.G.QQNQNQ.....QQR
 3653- 3674 (31.33/ 6.90)	SGMGQQGM..GQQgG.MGQPGM.....GSQ
 3703- 3721 (31.28/ 6.88)	HGMQQGAQ..QP...aMQQSGM.....QQ.
 3872- 3894 (35.27/ 8.77)	VPQQQQNQyfQPQ.Q.QQDQRM.....QQQ
 3895- 3919 (31.00/ 6.74)	PGGQQQ.Q..GHS.G.QQQNNQyynpnQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            14|     604.94|      39|      39|    2848|    2886|       2
---------------------------------------------------------------------------
 2762- 2800 (38.06/ 8.06)	...........Q.......QQ...P..HPGMQ....HQGMG...........S...GMG.AGMGGM........N..........................pTMHA..........PP.PY.SSSSM
 2842- 2884 (44.30/10.72)	H........qkL.....aqQQ...Q..LIEQQ....NRQRE...........A...RER.EAREHQ........E...........................RLAR..........EA.KI.REEQM
 3015- 3047 (47.26/11.98)	Q..........Q.......QR...QraLMEQQ....QRQQM...........M...NQQ.Q...........................................QQ..........QA.PY.GQQQP
 3048- 3094 (44.91/10.98)	QgqppsyqqssY.......QN...P..SGYQQ....GQQ.............S...GQN.QPPNYQ........Q...........................TSHT..........NP.AM.QNPSM
 3095- 3143 (49.11/12.77)	Q..........QaqqppayQQdnsQ..MNMQQ....NRQQQ...........Y...GNQ.SQQSQQ........A...........................QQGQ..........YP.QQ.YPQQL
 3144- 3165 (35.31/ 6.89)	N..........Q.......NQ...Q..M........NQQQ.........................Q........Q...........................RNPF..........GA.....QPEM
 3287- 3346 (45.58/11.26)	Q..........G.......QQ...Q..QGGMQ....NYQNQpvlgqpgpmqtG...GQA.GQQQQQ........N...........................QFQRqgmhttptknEM.AM.RQGQM
 3399- 3436 (50.30/13.27)	Q..........P.......QN...Q..FAGQQ....QQMGQ...........N...QGQ.TLQQGQ........N...........................QFGR..........QA.AS..NQEA
 3437- 3504 (37.02/ 7.62)	G..........F.......QQ...Q..PGFNQ....N.PGQ...........NyqrPEQ.QQQQNQ........NqwnqqnqqmrpqqpqqpsqqqqnvpfgRNEQ..........QQ.QF.QQSQH
 3505- 3550 (39.25/ 8.57)	Q..........Q......qNK...P..AMGQQgfnyQGQQQ...........Q...GQGfDQSSQQ........A...........................QQHQ..........NPtHH.QQGHM
 3551- 3596 (37.00/ 7.61)	Q..........Q.....qnPQ...Q.....QQ...yNQTQQ...........S...SQQ.QQQGNQfpgfsgssN...........................Q.AR..........SS.NI.LSQSM
 3760- 3789 (47.78/12.20)	Q..........Q.......HQ...Q..M..PQ....QNQQ............A...QQR.QMPGGG........V...........................QL.............P.P..Y..SM
 3790- 3823 (40.03/ 8.90)	...........G.......QQ..........Q....QTQQQ...........Q...PNQ.QQMDQL........R...........................RQQQ..........MQ.QMaRQQAM
 3824- 3852 (49.04/12.74)	Q..........Q.......QQ...G..V..QQ....GQPQM.....................QGYG........N...........................QGQQ..........QQ.QF...PQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     343.28|     102|     109|     466|     574|       3
---------------------------------------------------------------------------
  471-  573 (177.68/105.17)	PEEGPEEDPSKSvPSPTSSAGPAS.IEDDCWR....TRGLVPQTVAKPAP..EPVQQPVPQPPPKNLNIKSE.PVDLEYEKNFGNPVKSKNFNINIKAEPMDYDEYSTEPP
  575-  684 (165.60/87.91)	PLQPPQTFQQRP.ETPEKEKAPEQpAEPPRWTlaelPKDFFSKNLEVPAPwtRPREKPIERKRGYNLLCTDRfPVNEDVFEEFKDPDSPDGSRPASPVEPIPFKKLHKTPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     294.79|      95|     109|    1205|    1312|       4
---------------------------------------------------------------------------
 1205- 1312 (135.06/173.31)	ADENWLPGGADvlqYGRIIDACVdviGLMdcINVEKPKsIYNVSQRLFNFREKFAKEEAL.....LRIKLMFKwcISEEREGSFRPvYCARMLEYGLTRSVDGLIGGWQiMDL
 1318- 1417 (159.73/139.77)	ATEGPKPGMAN...YQAKFDACA...GIM..IELIRHK.LFTVADILRELEKDLDIDYTLplmarQRKQKMPK..ISKKEKTPEEP.DNTKLIHFTTEHTPKRLFMGRK.MDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     385.69|     102|     109|    2214|    2318|       5
---------------------------------------------------------------------------
 2141- 2208 (81.95/50.06)	..................................FGDISKY..WLLAPLV..RMCP........KPIN.IPP..QYAN....THVQtVASKFLKEasaLMDTPPTTTPKER.LLQ.....CSWAMSK..
 2216- 2318 (182.08/131.34)	LTCLACEKTQNGKDTFlNSV......YQQLQREVFRDHNKRSKWTNRPEH..RDCTV.......LRVNLIAY..MYKEILKPTHVE.VWGLLLYQ...LMFHGIINPSRERYVFE.....NCYDMLQHM
 2320- 2429 (121.67/76.48)	LWTLVNGDNMNSHDRY.GSIrvrwpnYAGLMKKI......RKEIQDRHVHpsRTCLLrflpigkLQTSTISYkkYHKRTIRPSAVK.SK.....K...FMSNEGIRSGKYVYLPEekvktNAYD...HM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      83.06|      20|      20|    2938|    2957|       6
---------------------------------------------------------------------------
 2938- 2953 (22.48/ 9.73)	.......KEQERQARLEAERLKR
 2954- 2975 (30.47/16.51)	EAEEremRERERQ.RLEQERLQR
 2976- 2998 (30.10/16.20)	EMEEkarREKEEQARIERERLER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.07|      30|     109|    1757|    1793|       7
---------------------------------------------------------------------------
 1757- 1793 (54.28/56.46)	ANVTANDPPLSEYWIGA......IRGLCClsmdirdPRD.PLSL
 1862- 1898 (47.79/33.09)	ANKTTETRTLSEAEPGVclslliIAGLCC.......PGDePFGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     355.23|      91|      98|     847|     944|       8
---------------------------------------------------------------------------
  759-  843 (93.98/68.43)	...........TSPSASPAPDTDKED.DDGKAKEGGDKA..AE..............KSTDKSAGEKEASE...........KEKTTDgkKDGDKPAeekskkDGkaaEEKKTVDEHLNDLIIP
  847-  944 (143.26/131.26)	EAEAASKRnsaTNSKDDEAEDANKVA.GDAPVVEATPAAGTSE..............KHPEAEVTQVETNDVEMesvdSETNKESTSD..PTADKPS......NG...EEPMEVDDPQKKLPSP
  949- 1042 (117.98/90.09)	EGDDASKK.....SKEGEKPDAPAIElVDLEALDDIPLPTDDLmlpdedeiqviekpKHPDADFCEV....VEV....VEKDKDKTPE...TA...G......EG...EKGAE.KEPE.KIPEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.47|      31|     106|     269|     303|       9
---------------------------------------------------------------------------
  269-  303 (40.31/40.46)	FQDGVVDKHEFLnDLTETFNvfFIkGSLANAKILE
  375-  405 (59.16/38.77)	FKDYIGDHKEFI.DPDDFFR..FV.NDLPDAAYFE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     164.48|      45|      61|    2637|    2691|      11
---------------------------------------------------------------------------
 2577- 2636 (41.18/18.72)	.....TAKDTE......KDTS..APTDAAKAAAApvaaapdankemdtstpkpapvtrETS.TTR.GRGGGRKRN
 2637- 2681 (77.83/74.48)	SGGRATGGSRA......KRTNSRANANAETAAAA........................ETSATTKAGASGGGSSN
 2697- 2740 (45.48/25.87)	SSDETKANIRNllnrkqEKRNSLADANAAAAVAA........................AAAAA..AAASG.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     167.68|      21|      37|    3682|    3702|      12
---------------------------------------------------------------------------
 3221- 3244 (22.53/ 6.19)	PR..FGENPQqnvPGFNRNLpyPQQQ
 3682- 3702 (44.78/22.14)	HGMGRSTMGQ...PGMQQSG..MQQQ
 3722- 3740 (43.05/20.91)	HGMSQSGMGQ...PGM..GG..MQQQ
 3741- 3758 (29.88/11.46)	NRNSFGSMGQ...QG.QQSG..QQ..
 3855- 3870 (27.45/ 9.72)	HR......GQ..gQGMGGAG..QQHQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.11|      10|      60|    2831|    2840|      16
---------------------------------------------------------------------------
 2831- 2840 (19.67/10.85)	EERARIMEEQ
 2909- 2918 (17.44/ 8.62)	EEAARRLEEQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16189 with Med12 domain of Kingdom Metazoa
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