Description | Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MSAPDRSSGEAAVPEYRIHHGGHDRFTLELEFVQMLANPQYLSYLADKKLLENEEFVAYLDYLQYFRDPTYLRYLQYPGPTLRALELLQEERFRKDILSPEVAGRLFHEGMEASTST |
Length | 117 |
Position | Middle |
Organism | Cercospora beticola (Sugarbeet leaf spot fungus) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Dothideomycetidae> Mycosphaerellales> Mycosphaerellaceae> Cercospora. |
Aromaticity | 0.13 |
Grand average of hydropathy | -0.524 |
Instability index | 44.51 |
Isoelectric point | 5.02 |
Molecular weight | 13663.20 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro |
Binary Interactions |
Repeats | >MDP16183 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 84.49| 23| 28| 19| 45| 1 --------------------------------------------------------------------------- 23- 45 (42.03/19.24) HDRFTLELEFVQMLANPQYLSYL 53- 75 (42.46/19.54) NEEFVAYLDYLQYFRDPTYLRYL --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) AAVPEYRIHHG 2) LQYFRDPTYLRYLQYP | 11 63 | 21 78 |
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