<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16129

Description Uncharacterized protein
SequenceMDNNNWRPAQAGGVAAAGEPNNNNNTSMGVEGPDWRSQLQADSRQRIVNKIMDTLKRHLPISGPEGLLELKKIAVRFEEKIYTAATSQSDYLRKISLKMLTMETKSQNNGVTNSLPQNPVASNQNPPDPASHSMQSQVLNQGHSSISLPNQPQARQQLLSQNIQNTTASGGIQSSSGLQSAFPSVTGLTPSTMPNAIGQNSTLQNISGISQNSVGQGVPSNIFSNTQRQMQGRQHPQQVVSQPNQQQPTNSQQYMYQQHQNQMMKQKLQQGNIQPSLMQSHIQPQQNLLQSTQLQPSQQSLMQMSSSLQGNQSTQQTQPSMMQSASHSGFQQNQQPSVQQSTASVLQQHTQSVLRQQPQSQQSLHQQSTGLHQQQPSIPQQQQTLAGQQQNATNIQQQKNQQLIGQQNSVTDLQQSQQQQQRLLGQQNNLSNMQQQLLGQQNNISSMNQQQIGSQNGVGLQPQQLLGTQSSVSNMQSHQQSMHLLSQQAKVGGQQQQSTQASLMQIPGQQSQSQPLQPQLMPQLQSQPAQFQQQLGLQHQPNQLQRDMQQRLNSSVIQPPNVAEQKQIQSQRVLPEASSTSMDSTSQTGQANTADWQEEAYQKIKAMKEMYLPDLLEMHHKLSVKFQQHETVAQQPKDQMDKLRLMKIYLERIITFLQVSKNNIPLTHRDKLPGYEKQIISFLNSNRTKKPVPANQQQLQPSGGHTLSMPQQQQPQSQIPQLQQHDNQMNSQMQPMNVPNSVTPEQQTAGTNMSHSSLPLSNHMGVSPMQGMNSLQSGSALEMGQGSVPSSLQHGGMGSRQQNSVNAPSQANMNTLPQGGVNGLQPNINSLQLTSNMLQQQHLKQQQEQQLLQSQQMKQQQQQQLQRQMHQQMLQQQKQQVQQQHQQHPQMQQQQQQQQLQQQQQQKQQLPAQFQAHQMPQLHQMSEDLKMRQAMGFKQGMAPQHHSAGQRAPYHHQQLKPGAQFPISSPQILSAASPQISQHSHSSPQIDQQSLLTFSKSGTPLQSANSPFIVPSPSTPLAPSPLPGDPEKQASGVSSLSNAGNIGHPQTSTALSQAQSLAIGTPGISASPLLAEFIGTDSNQGTEQPLERLVKAVKSISTKAFSASVSDIGSVISMIDRIAGSAPGNGSRAAVGEDLVAMTKCRMQARNFITQDGVSATKKMRRDTSAMPLNGFSSAGSVTDSFKQRNGLEMSDLESTATSRIKRPRIEANPALLEEIKEINLRLIDTVVEISDEDIDPVTVAAAAEGGQGTLVKCSYTAVALSPNLKAQYASGQMSPIMPLQLLIPTNYPNCSPVLLDKLPVDLSKEYDDLSLKTRSRFSISLRSLSQPMSLKEMAKAWDLCARAVIAEYAQKSGGGTFSSRYGTWKKCVSAA
Length1376
PositionTail
OrganismAquilegia coerulea (Rocky mountain columbine)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Ranunculales> Ranunculaceae> Thalictroideae> Aquilegia.
Aromaticity0.03
Grand average of hydropathy-0.792
Instability index74.15
Isoelectric point9.52
Molecular weight151345.65
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16129
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     161.97|      30|      30|     435|     464|       3
---------------------------------------------------------------------------
  438-  464 (44.78/ 9.64)	LGQQNNISSMNQQQIGSQNGVGLQPQQ....
  521-  547 (38.39/ 6.86)	MPQLQSQPAQFQQQLGLQH....QPNQlQRD
  838-  865 (40.92/ 7.96)	LQQQHLKQQQEQQLLQSQ.QMKQQ.QQ.QQL
  891-  918 (37.88/ 6.64)	MQQQQQQQQLQQQQQQKQ.QLPAQFQA.HQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      58.90|      12|      16|     961|     972|       6
---------------------------------------------------------------------------
  961-  972 (23.22/12.03)	PG.AQFPISSPQI
  978-  990 (18.20/ 7.06)	PQiSQHSHSSPQI
 1015- 1026 (17.48/ 6.34)	PS.PSTPLAPSPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     146.96|      26|      30|     108|     135|      11
---------------------------------------------------------------------------
  119-  151 (30.90/ 7.88)	PVASNQNPPDPASHsmQsqvlNQGHSSiSLPNQ
  222-  247 (36.60/ 6.80)	IFSNTQRQMQGRQH..P....QQVVSQ.PNQQQ
  691-  712 (37.63/ 7.21)	PVPANQQQLQP.SG.........GHTL.SMPQQ
  713-  737 (41.83/ 8.89)	QQPQSQI.PQLQQH..D....NQMNSQ.MQPMN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.74|      13|      15|    1132|    1144|      13
---------------------------------------------------------------------------
 1132- 1144 (21.30/13.23)	RAAVGEDLVAMTK
 1150- 1162 (22.44/14.30)	RNFITQDGVSATK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.57|      22|      36|     590|     612|      16
---------------------------------------------------------------------------
  590-  612 (35.44/28.51)	QANT.ADWQEEAYQKIKAMKeMYL
  628-  650 (35.14/22.79)	QHETvAQQPKDQMDKLRLMK.IYL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.14|      10|      15|     797|     806|      18
---------------------------------------------------------------------------
  797-  806 (18.21/ 8.72)	MGSRQQNSVN
  813-  822 (18.94/ 9.41)	MNTLPQGGVN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.85|      16|      16|    1279|    1294|      20
---------------------------------------------------------------------------
 1279- 1294 (29.69/18.96)	SPIM..PLQLLIPTNYPN
 1296- 1313 (22.16/12.18)	SPVLldKLPVDLSKEYDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.67|      14|      93|     152|     165|      21
---------------------------------------------------------------------------
  152-  165 (24.42/ 9.91)	PQARQQLLSQNIQN
  248-  261 (27.24/12.05)	PTNSQQYMYQQHQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.39|      11|      16|      80|      90|      24
---------------------------------------------------------------------------
   80-   90 (18.80/12.49)	KIYTAAT.SQSD
   98-  109 (15.59/ 8.79)	KMLTMETkSQNN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16129 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MDNNNWRPAQAGGVAAAGEPNNNNNTSMGVEGPDWRSQLQADSRQRIVNKIMDTLK
2) METKSQNNGVTNSLPQNPVASNQNPPDPASHSMQSQVLNQGHSSISLPNQPQARQQLLSQNIQNTTASGGIQSSSGLQSAFPSVTGLTPSTMPNAIGQNSTLQNISGISQNSVGQGVPSNIFSNTQRQMQGRQHPQQVVSQPNQQQPTNSQQYMYQQHQNQMMKQKLQQGNIQPSLMQSHIQPQQNLLQSTQLQPSQQSLMQMSSSLQGNQSTQQTQPSMMQSASHSGFQQNQQPSVQQSTASVLQQHTQSVLRQQPQSQQSLHQQSTGLHQQQPSIPQQQQTLAGQQQNATNIQQQKNQQLIGQQNSVTD
3) QQSQQQQQRLLGQQNNLSNMQQQLLGQQNNISSMNQQQIGSQNGVGLQPQQLLGTQSSVSNMQSHQQSMHLLSQQAKVGGQQQQSTQASLMQIPGQQSQSQPLQPQLMPQLQSQPAQFQQQLGLQHQPNQLQRDMQQRLNSSVIQPPNVAEQKQIQSQRVLPEASSTSMDSTSQTGQANTADWQEE
4) QSANSPFIVPSPSTPLAPSPLPGDPEKQASGVSSLSNAGNIGHPQTSTALSQAQSL
5) YEKQIISFLNSNRTKKPVPANQQQLQPSGGHTLSMPQQQQPQSQIPQLQQHDNQMNSQMQPMNVPNSVTPEQQTAGTNMSHSSLPLSNHMGVSPMQGMNSLQSGSALEMGQGSVPSSLQHGGMGSRQQNSVNAPSQANMNTLPQGGVNGLQPNINSLQLTSNMLQQQHLKQQQEQQLLQSQQMKQQQQQQLQRQMHQQMLQQQKQQVQQQHQQHPQMQQQQQQQQLQQQQQQKQQLPAQFQAHQMPQLHQMSEDLKMRQAMGFKQGMAPQHHSAGQRAPYHHQQLKPGAQFPISSPQILSAASPQISQHSHSSPQIDQQSLLTFSKSG
1
102
414
1006
675
56
412
599
1061
1002










Molecular Recognition Features






MoRF SequenceStartStop




NANANA