<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16119

Description Uncharacterized protein
SequenceMQRYPAASCGGGISNHSVGGASVRDTARADTSFPSSNFSLNPRRPLQLAPYKLTCEKEPLSARLGPPDYYPQTPNCPEETLTRDYVQHGYKETVDGLEEAREITLSQIGTFSKPVVVKCKEAIRKRLRAINESRAQKRKAGQVYGVPLSGSLLTRPCVFPEQRPCGEDFRKKWIESLSQQHKRLRLLAENVPHGYRRKSLFEVLIRHNVPLLRATWFIKVTYLNQVRPISTSVSSGAPDKTQLARSELWTKDVVEYLQYLLDEFFSKDGSMSTPQARNQSSQMLLVGCIQQKGDSSPAFFDGDEPSFHFKWWYMVRILQWHHAEGLLIPSQIIEWVLNQMQEKESFETLELLLPVVFGVLETIALSQTYVRTLVEVAVRCIQEPSPGGSSLLDNSRRAYMISSLVEMLRYLIVAVPDTFVALDCFPLPSCLLSEAANDRSFLLKDGERIPNGEMDFANTSIDKGLDIQNKFLSFDHTISSIQKRVDNLVKAVSPGVQGNGMAKAVQALDKALILGDVKEAYKYLFEDLCDHDVEEVWIAEVSPCLRASLKWIGTVSLSLVCSVFFVCEWATCDFRDCRTAIPPGLKLTGRKDYSQVYIAVQLLKLQMEVIHSSGQCKEGILWGTESIVKGGSQRDSFPVATAAETMAVNKSKSKIAGGKIDAEDIFQSPGPMHDIVVCWIDQHEVGKGEGYKRLQLLIVELISAGIFYPQAYVRQLIISGVMERNETPVDLGRRQRHYRILKQLPGSYLMDFFKEARVTSIPLLSEAMQVYSNERRFVLHGLSTSNNNGNDTNCVPKTQKDNSASGREAASPASSIKTKVRHSASSPLAVRDASAKSLVAELKNAISTLLSIPHSFSALANTREDSQGVKRPIGLSGTVVESVEGTDGCEECKRAKRPKLGEERSSYQLGIPSNPLDDEDAWWVKKGSKSLESFKVDPPLKSTKNVSRGRRKTQSLAQLAAARIEGSQGASTSHICDNKISCPHHRSGVEGENSKTEGSRKTHLSDIIKIGKALKRLRLLERRTITLWLMTIVRQLVEGNEKPAAKVGQNPGSVPPDDRATPSWKFGEHELFAIIYLMDVASDLVSATKFLLWLLPKISNGLSSTLPSGRSLLIMSKNAEAHVCEVGEAFLLSTIRRYENVIVVNDLLPEALSAMMRQAAAVMVSNGRASSSSAFNYARNLLKKYGSSGSVAKWEKNFRATCDQRLLTELESGRSLDGEFGFSSGVPAGVEDFDSYLHQKITGRLSRPAPSMKEVVQRYTEEAVQYFYDKERKLVGSSTQKSPGIEKWDDEFQMAQKIVLALMDCIRQNGGATQEVDHSLVAAAVAAIVSNVGLAVAKMPDFTTSGNHPKLPSPVSLLSCAWRIVHIHITCLSLLKEALGERQCRVFEIALATEASSAVAGSFAPGKVSRGQFPEGHDANMSNQIVNNSAKSVLGRATKAAAAVSALVIGAIVHGVVSLERMVTVFRLKEGLDILHFIRSARSNSNGISRSIGMLKVDHSIEICVHWFRLLIGNCRTVSDGLVVELLGEPYIVALSRMQRMLPLSLVFPPAYSTFAMVIWRPYLLNGNITAREDVQVYQSLTVAIADAIRHQPFRDVCLRDSSALYDLLASDVGDSEFAAMLELHGPDKHLKTVAFVPLRARLFLNAILDGKVPQSMLAHGDASRVTGHGESKVQYAENEMKLINQLVHVLDTIQPAKFHWQWVELRLLLNEQVLIEKIEGPYNMSVVEAIRSLLPNSDNVNLSENENNFTDIVLTRLLVRPDAASLYSEVVHLLGRPLEESLLLHAKWFLAGHDVLFGRKSVRQRLINIAQNRGLSTKIQFWKPWGWTSSAVDTMANRVDKKFEPSSLEEGEVVEEGMDLKRSGKMTSQTPDTEGSTSRQQYATERALAELVLPCMDRSSSDARNTFANELIKQLNSIEIQINLVAGGSSKQAGIMPLGVEGAANKGNTRKGIRGGSPGLGRRSMGASDSAPPSSAALRASLWLRLQFLLRLLPVIHADREPSSRNMRHLLASVILRLLGSRVVYEDIDSCSSPMQNSFKRLDSLLESSVSAASGNLFGESLFDQFLSVLYGLLSSWKPRWLKPKSSSKSTAKSPRDFSVFDREVAESLQTDLDRMLLPETIRWRLQAAMPVLSRFPSCSISCQPPTVSTAALASLQFSISSPGFQHGNSSQSQRNRASANTPGKSKSLLSQDQEMEIDPWTLLEDGTGSGPSTSNSIVGVVGDHTNLKACHWLKGAVRVRRTDLTYIGAVDDDS
Length2256
PositionKinase
OrganismAquilegia coerulea (Rocky mountain columbine)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Ranunculales> Ranunculaceae> Thalictroideae> Aquilegia.
Aromaticity0.07
Grand average of hydropathy-0.214
Instability index44.27
Isoelectric point8.72
Molecular weight249097.98
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16119
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     208.57|      67|     608|     863|     943|       1
---------------------------------------------------------------------------
  864-  939 (103.43/75.29)	EDSQGVKRpiglSGTVVESVEGTDGceeckRAKRPKLGEERSSYQLGIPSNPLDDEDA..WWVKKGSKSLESFKVDPP
 1856- 1924 (105.14/55.28)	EEGMDLKR....SGKMTSQTPDTEG.....STSRQQYATERALAELVLPCMDRSSSDArnTFANELIKQLNSIEIQIN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     284.64|      94|     825|    1204|    1305|       2
---------------------------------------------------------------------------
 1204- 1305 (143.64/107.38)	QRLLTELESgrSLDGEFGFSSGVPAGVEDFDSYLhQKITGRLSRPAPS.MK.EVVQRYTEEAVQYF..YDKErklVGSSTQKS......PGIEKWddEFQMAQKIVLALMDC
 2037- 2140 (141.00/83.21)	QNSFKRLDS..LLESSVSAASGNLFGESLFDQFL.SVLYGLLSSWKPRwLKpKSSSKSTAKSPRDFsvFDRE...VAESLQTDldrmllPETIRW..RLQAAMPVLSRFPSC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.63|      29|     608|     757|     809|       8
---------------------------------------------------------------------------
  427-  458 (43.07/15.18)	LPscLLSEA....ANDRSFLLKdGERIPNGEMDFAN
  761-  793 (46.56/55.11)	IP..LLSEAmqvySNERRFVLH.GLSTSNNNGNDTN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     210.26|      70|    1353|     298|     394|      10
---------------------------------------------------------------------------
  319-  394 (97.87/107.05)	QWHHAEGLLIpSQIIEwVLNQMQ.EKESFETLELLLPVVFGVL.ETIalSQTYVRTLVEvAVRCIQePSPGGSSLLDN
 1675- 1746 (112.39/56.61)	QYAENEMKLI.NQLVH.VLDTIQpAKFHWQWVELRLLLNEQVLiEKI..EGPYNMSVVE.AIRSLL.PNSDNVNLSEN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.04|      17|     825|     189|     213|      13
---------------------------------------------------------------------------
  195-  213 (27.81/31.05)	YrrKSLFEVLIRHNV.........PLLR
  521-  546 (29.23/10.59)	Y..KYLFEDLCDHDVeevwiaevsPCLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.64|      15|     136|     156|     173|      16
---------------------------------------------------------------------------
  156-  173 (27.47/26.50)	PCVFPEQRPcgeDFRKKW
  297-  311 (32.17/19.87)	PAFFDGDEP...SFHFKW
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16119 with Med12 domain of Kingdom Viridiplantae
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