<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16105

Description Uncharacterized protein
SequenceMGEGGGNSRNNNNNNSNRPAWLQQYDLIGKIGEGTYGLVFLAKIKSQPNRGKSIAIKKFKQSKDGDGVSPTAIREIMLLREINHENVVKLVNVHINSSDMSLYLAFDYAEHDLYEIIRHHREKVNQSINQYSVKSMLWQLLNGLNYLHSNWIIHRDLKPSNILVMGEGDEQGVVKIADFGLARIYQAPLKPLSENGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGVEVKATPNPFQLDQLDKIFKVLGHPTPEKWPTLVNLPHWQTDQQHIQGRKYENPGLYSVVHLSQKSPAYDLLSKMLEYDPRKRITAAQALEHEYFRIDPLPGRNALVPCQPGEKIVNYPARPVDTTTDFEGSTSVQPPQPVSSGNAMSGSGVPPMVAARPLPRNMPPMAGMQRMPGPGMSAYNLASQAAMGGGMNPGGIPMQRGAGGQPHQQQQLRRKDPGMGMPGYPPQKSRRF
Length475
PositionKinase
OrganismAquilegia coerulea (Rocky mountain columbine)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Ranunculales> Ranunculaceae> Thalictroideae> Aquilegia.
Aromaticity0.08
Grand average of hydropathy-0.477
Instability index41.51
Isoelectric point9.37
Molecular weight52833.97
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP16105
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     142.17|      37|      44|     384|     422|       1
---------------------------------------------------------------------------
  384-  422 (68.13/42.27)	GNAMSGSGVPPMVAARPLPRNMPPMagMQRMPGPGMSAY
  431-  467 (74.05/40.57)	GGGMNPGGIPMQRGAGGQPHQQQQL..RRKDPGMGMPGY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.28|      34|      44|     163|     199|       2
---------------------------------------------------------------------------
  163-  199 (49.26/39.96)	LVMGEGDEQGVVKIADFGLarIYQA..PLKPLSEnGVVV
  208-  243 (56.03/34.33)	LLLGAKHYTSAVDMWAVGC..IFAEllTLKPLFQ.GVEV
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP16105 with CDK8 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) PCQPGEKIVNYPARPVDTTTDFEGSTSVQPPQPVSSGNAMSGSGVPPMVAARPLPRNMPPMAGMQRMPGPGMSAYNLASQAAMGGGMNPGGIPMQRGAGGQPHQQQQLRRKDPGMGMPGYPPQKSRRF
348
475

Molecular Recognition Features

MoRF SequenceStartStop
1) HQQQQLRRKDPGMGMPGYPPQKSRRF
2) IAIKKFK
450
54
475
60