<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16027
Description |
Mediator of RNA polymerase II transcription subunit 14 (Fragment) |
Sequence | MVPLSTAIGRIITFAYTELVTLVDTLASRSESDRRSEILKYTEHMSDLLTKLLVLVRWAKHAPQIQKCQNVIAYLDSQNRYFDYAVDSIYATFLSMPGVRMRNYDVGNAVDILTTGTYQRLPTAISRAVPPPKLTKRQMRETLNAIDAIIRSRILKGEPLPSAMRTYKIANGRIIFMVQKEFEATLTLLQFEKDIPWHIVNVKLLV |
Length | 206 |
Position | Tail |
Organism | Coemansia reversa (strain ATCC 12441 / NRRL 1564) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Fungi incertae sedis> Zoopagomycota> Kickxellomycotina>
Kickxellomycetes> Kickxellales> Kickxellaceae> Coemansia.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.020 |
Instability index | 48.51 |
Isoelectric point | 9.64 |
Molecular weight | 23561.31 |
Publications | PubMed=25977457
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU365082
|
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:UniProtKB-UniRule
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP16027
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 81.97| 25| 114| 4| 40| 1
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4- 28 (39.71/17.27) LSTAIGRIITFAYTELVTLVDTLAS
121- 145 (42.26/19.19) LPTAISRAVPPPKLTKRQMRETLNA
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|