Description | Uncharacterized protein |
Sequence | MDELSATGAGTHVDRVTQLQDSADEQCKMLFSSLHYLHKKAGMVQVSPEIPITQQNEGADSASEFSLRTKEIATDICRQAKKIDALIESLPGVAVSENEQMREFDKLNQENEVATQELHEADQRARALLDCLSKAMRDIADNSGKA |
Length | 146 |
Position | Middle |
Organism | Coemansia reversa (strain ATCC 12441 / NRRL 1564) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Fungi incertae sedis> Zoopagomycota> Kickxellomycotina> Kickxellomycetes> Kickxellales> Kickxellaceae> Coemansia. |
Aromaticity | 0.03 |
Grand average of hydropathy | -0.569 |
Instability index | 37.39 |
Isoelectric point | 4.79 |
Molecular weight | 16103.81 |
Publications | PubMed=25977457 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP16025 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 61.62| 20| 39| 71| 90| 2 --------------------------------------------------------------------------- 71- 90 (32.68/20.62) EIATDICRQA.KKIDALIESL 112- 132 (28.94/17.58) EVATQELHEAdQRARALLDCL --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) ADSASEFSLRTKEIATDICRQAKKIDALIESL 2) EQMREFDKL 3) QRARALLDCLSKAMRDIADNS 4) VQVSPEIPITQQNE | 59 99 123 44 | 90 107 143 57 |
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