<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16010

Description Mediator of RNA polymerase II transcription subunit 16
SequenceMAADAIITDSGAMHVAGVPIVNPSTVVVWEVTPGPGNGFQATPKTSVSNGVPPSLNPPSWDGYAPLAAYLLSSQEYLLQEAKQGKKLTEQHYSDMVTLHCSPVSNFSAYVSPEAAAQSTATTTWGSGVTAVAFDPTRGGSVIAVVIVEGQYMSPYDPDEGPSITGWRVQRWESSVEDVVLHQIFGNPTSSFGGQAPKQTVWVSKVNKCIPAGNDFKRPQAAGAGPISNGRNMADSGVEMGKRVSFDPFDLPSDVRTLARIVYSAHGGEIAVAFLRGGIHVFSGPSFTPVDNYHIDVGSAIAAPAFSSTSCCSASVWHDTNRDCTILKIIRVLPPAVPSNQVKANSANWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVALNSVIDVLDADFHSLPSTQHRQQYGPSLDRIKCRLLEGTNAQEVRAMVLDMQARLLLDMLGKGIQSALTNPSSLVPEPWQASSETLFGIDPEAMAVEPALVPSIQAYVDAILDLASHFITRLRRYASFCRTLASHAVTAGTGGSRSMVTSPTQNASSPATSQGAQGGTANSTGSTQMQAWVQGAIAKISSTADSVPSSAPNPITGPSTFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLHFCFFFRRTQLPCFMGAAQRNADGSMQKPQPSIPGKAEDSISGAKPTPGGQVGAGVKGSEEGPSKRSRIGSGNAGQGYTFEEVRVLFLILMDLCRRTAGLAHPLPVSHVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGPWSDSEDTGVDDNSKLSPSRDLTECSSSENCDVYYGAHGLWPRKRRMSERDAAFGLNTSVGLGAYLGIMGSRRDVVTAVWKTGLEGVWYKCIRCLRQTSAFASPSGNPSTSQNEKEVWWISRWAYRCPMCDGCWVRVV
Length938
PositionTail
OrganismCapsicum chinense (Scotch bonnet) (Bonnet pepper)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Solanoideae> Capsiceae> Capsicum.
Aromaticity0.08
Grand average of hydropathy-0.173
Instability index45.26
Isoelectric point6.28
Molecular weight100640.41
Publications
PubMed=29089032

Function

Annotated function 
ECO:0000256	RuleBase:RU365082
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats
>MDP16010
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     465.22|     144|     563|     210|     372|       1
---------------------------------------------------------------------------
   33-  177 (206.38/98.49)	PGpGNGF...QATPKTSVSNGVPPSLNPPSWDGYAPLAAYLLSSQEYLLQE...AKQGKKLTEQHYSDMVTLHC....SPVSNFSAYVSPEAAAQSTATTTWGSgvTAVAFDPTRGGSVIAVVIVegqyM........SPYDPDEGPSITGwrvQRWESSVED.................
  210-  371 (223.76/144.83)	PA.GNDFkrpQAAGAGPISNGRNMADSGVEMGKRVSFDPFDLPSDVRTLARivySAHGGEIAVAFLRGGIHVFSgpsfTPVDNYHIDVGSAIAAPAFSSTSCCS..ASVWHDTNRDCTILKIIRV....L........PPAVPSNQVKANS...ANWERAIAErfWWsllvgVDWWdAVG
  877-  926 (35.07/ 9.05)	..........................................................................................................TAVW.KTGLEGVWYKCIRC....LrqtsafasPSGNPS.....TS...QN.EKEV....WW.....ISRW.AYR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     262.61|      78|     114|     485|     566|       2
---------------------------------------------------------------------------
  485-  566 (122.32/71.56)	PSIQAyVDAILDlaSHFITRLRRYASFCRTLASHAVTAGTGGSRSMVTSPTQ..NASSPATSQGAQGGtANSTGSTQMQAWVQG
  603-  682 (140.30/69.95)	PGTPA.VRLIGD..CHFLHRLCQLLHFCFFFRRTQLPCFMGAAQRNADGSMQkpQPSIPGKAEDSISG.AKPTPGGQVGAGVKG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16010 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAQRNADGSMQKPQPSIPGKAEDSISGAKPTPGGQVGAGVKGSEEGPSKRSRIGSGN
2) GTGGSRSMVTSPTQNASSPATSQGAQGGTANSTG
641
523
697
556










Molecular Recognition Features






MoRF SequenceStartStop




NANANA