<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15980

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMDGNNWRAAQGGGDSGAAGGAAGTVAGAMDSGDWRTQLLPDSRQRIVNKIMETLKRHLPVSGQEGVQELKKIAVRFEEKIYSAATSQQDYLRKISLKMLTMETKSQNPMTNSVQPNSASSGQNALGPGSNSMQSQVNSQAQQLPGPMVTNQTQTRQPLLQQNIQNNMASTGLQNSASLTPALPPGSNLTHGAMPNVVGQNSNLQNMPNVGQNSVGNAIGQGMPPNMVANSQRQMQGRQQQVASQQQQQFYQQQLHHQMIKQKFQPGNTSQSLMQSHMQQQPQEQQQQQQQQQPQQQQNLLQPTQTQPSQQAMMQPSSMQSTSLSNLQQNQQSTVQQSTQSVLHQRQQSVMRQQQTPMLHQQQSSMLQQPILPAQQQQQQQLIAQQTNVANLQQNQLIGQQNTMSDVQQRLVGQQNNLNSLQQQQQLLNQQNNFQNMHQQQLGSQSNISGVQQQQLSGSQQPGNSGLTSNQHPIHMMQQPKVPVQQQMLQSSTTVLPSQGQQSQSQPAQQQMMSQSQSQPGQLQPPLGLQQQTNQLQREMQQRLQPSAPFLQQHNAMEQQKQLYQSQRAAPEASSTSLDSTAQTGNANAADWQEEVYQKIKSMKETYLSELNDLYQKIATKVQQHDSLPQRPQNEQIEKLKMFKMTLERIVLFLRLNKHDIQPTHKEKLFSVERHISFFLSSNRPRKPSSSPLQGQLPPSSMQLQQPQSLDGQTNSSMQPVQGSMAGMQQNNLTNLQHNSLSGVPTISNTQQHMINTVQPGSSVDLGQGNSLNSLQQVATGSLQQNPVNSPQQVNISSVSSQSGTNPVQAGLGSLQQNSNTLQQSLPKQHEHQMLQNQQQLRQQYHHRQMQQQIYQRQQLMQQQQAKQQQNALMPTHQLSQLHQMTDPNDLKMRQQMGMKPGVLQQQQSVGQRVGSHHPQLKPGISSPQLHQALSPQLTQHPSPQIDQQNMLASLTKGGTPLQSASSPFVVPSPSTPLAPSPMPGDSEKVCAGLASHTTAGNTMHQQATVASAPAQSLAIGTPGISASPLLAEFTPLDGTHGNVLSTVSGKPNVEQPLERLMKVVKNMSAKALDSSVSDISSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARNYFTQDGPTGTKKMKRYTTSNVVSSSGSLNDRFWQLNCSEAPELESTATSDVKRPRLEVNHALVEEIQDINRKLIDTVVEICDEGVDPSAQTAATEGGEGTTVKCSFTAVALSPNLKALYASAQMSPIQPLRLLVPINYPNCSPILLDKFPVEVSKEYEDLSMKAKSRFSVSLRSLSEPMSLKDIARTWDACARAVISDYSQLSGGGTFSSKYGSWEDCPTTA
Length1340
PositionTail
OrganismCapsicum chinense (Scotch bonnet) (Bonnet pepper)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Solanoideae> Capsiceae> Capsicum.
Aromaticity0.03
Grand average of hydropathy-0.772
Instability index68.45
Isoelectric point9.21
Molecular weight147193.96
Publications
PubMed=29089032

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15980
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            10|     519.94|      44|      44|     376|     419|       1
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  153-  205 (44.42/ 6.23)	Q..T........RQPL.L.QQniQN..NMAStgLQNSasltpALPPGS....NL.THGA.M.........PNV...........VGQNSNLQN
  244-  285 (49.30/ 7.77)	Q..Q........QQQF.Y.QQ..QL..........HH.....QMIKQKfqpgNT.SQSL.M.........QSH...........MQQQPQEQQ
  287-  325 (58.84/10.76)	Q..Q........QQQQ.P.QQ..QQ..NL....LQPT.....QTQPSQ....QA.M....M.........QPS...........SMQSTSLSN
  327-  373 (48.09/ 7.38)	Q..Q........NQQS.T.VQ..QStqSVLH..QRQQ.....SVMRQQ....QTpMLHQ.Q.........QSS...........MLQQPILPA
  376-  419 (75.13/15.87)	Q..Q........QQQL.I.AQ..QT..NVAN..LQQN.....QLIGQQ....NT.MSDV.Q.........QRL...........VGQQNNLNS
  421-  464 (59.78/11.05)	Q..Q........QQQL.L.NQ..QN..NFQN..MHQQ.....QL.GSQ....SN.ISGVqQ.........QQL...........SGSQQPGNS
  468-  504 (47.10/ 7.07)	S..N........QHPIhM.MQ..QP..KVP...VQQ......QMLQSS....TT.VLPS.Q........................GQQS..QS
  719-  773 (46.17/ 6.78)	P..V........QGSM.AgMQ..QN..NLTN..LQHN.....SLSGVP.....T.ISNT.Q.........QHMintvqpgssvdLGQGNSLNS
  852-  905 (44.96/ 6.40)	QiyQ........RQQL.M.QQ..QQ....AK..QQQN.....ALMPTH....QLsQLHQ.MtdpndlkmrQQM...........GMKPGVLQQ
  906-  953 (46.16/ 6.78)	Q..QsvgqrvgsHHPQ.L.KP..GI..SSPQ..LHQ......AL.SPQ....LT.QHPS...........PQI............DQQNMLAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.06|      13|      17|    1010|    1023|       5
---------------------------------------------------------------------------
 1010- 1023 (20.95/12.09)	AS...APAQSLAiGTPG
 1026- 1041 (20.11/ 7.38)	ASpllAEFTPLD.GTHG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.31|      18|      18|     516|     533|       7
---------------------------------------------------------------------------
  516-  533 (33.63/14.15)	QSQPGQ.LQPPLGLQQQTN
  536-  554 (27.68/10.04)	QREMQQrLQPSAPFLQQHN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.87|      10|      31|     776|     785|       8
---------------------------------------------------------------------------
  776-  785 (18.78/ 9.55)	QVATGSLQQN
  808-  817 (19.09/ 9.86)	QAGLGSLQQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.73|      16|      17|    1266|    1281|      10
---------------------------------------------------------------------------
 1266- 1281 (27.35/21.42)	KFPVEVSKEYEDLSMK
 1285- 1300 (26.37/20.34)	RFSVSLRSLSEPMSLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     168.18|      61|     114|    1045|    1116|      11
---------------------------------------------------------------------------
 1045- 1116 (80.69/72.89)	STvSGKPNveqplERLMKVvkNMS.AKALDSS.VSD.......................ISSVVSMIDRiaGSAPGNGSRAAVGEDLVAMtKCRLQA
 1141- 1226 (87.49/49.53)	SS.SGSLN.....DRFWQL..NCSeAPELESTaTSDvkrprlevnhalveeiqdinrklIDTVVEICDE..GVDPSAQTAATEGGEGTTV.KCSFTA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.68|      13|     114|     703|     717|      12
---------------------------------------------------------------------------
  703-  717 (18.92/12.23)	LQqpQSLDGQTNSSM
  821-  833 (25.76/10.82)	LQ..QSLPKQHEHQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.72|      14|      25|       1|      15|      13
---------------------------------------------------------------------------
    1-   15 (25.05/19.87)	MDGNNWRAaQGGGDS
   29-   42 (28.67/17.83)	MDSGDWRT.QLLPDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.58|      19|      95|     123|     142|      16
---------------------------------------------------------------------------
  123-  142 (30.65/19.78)	NALGPG......SNSmQSQVNSQAQQ
  216-  240 (29.93/13.84)	NAIGQGmppnmvANS.QRQMQGRQQQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15980 with Med15 domain of Kingdom Viridiplantae
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