<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15945

Description Mediator of RNA polymerase II transcription subunit 19a
SequenceMDPDSKRFGRGPGELTGAVDLISHFKLLSHHEFFCKRSLPLSISDTHYLHNVVGDTEIRKGEGMQLDQLIQDTSLSRETSSCIQPFDLDALGEAFQLREAAPVDLPHSEKGIPTVAGKSKSESKDKEKKHKKHKDKDKEKDKEHKKHKHRHRDRSKDKDKDKKRDKSVHHDSGADHSKKHHEKKRKHDGEEELNDVHKHKRSKHKSSKIDEIGAIKVAG
Length219
PositionHead
OrganismCapsicum chinense (Scotch bonnet) (Bonnet pepper)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Solanoideae> Capsiceae> Capsicum.
Aromaticity0.03
Grand average of hydropathy-1.386
Instability index40.30
Isoelectric point9.31
Molecular weight25045.80
Publications
PubMed=29089032

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15945
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.56|      14|      33|     140|     172|       2
---------------------------------------------------------------------------
  159-  181 ( 8.78/ 8.03)	DKDKKrdksvhHDSgAdhSKKHH
  182-  195 (22.78/11.51)	EKKRK......HDG.E..EELND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.55|       9|      45|     149|     158|       3
---------------------------------------------------------------------------
  149-  158 (14.01/ 9.05)	HRHRdRSKDK
  197-  205 (18.54/ 7.59)	HKHK.RSKHK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      67.46|      17|      21|      62|      78|       4
---------------------------------------------------------------------------
   49-   61 (13.75/ 8.02)	....LHNVVGDTEIRKG
   62-   78 (27.84/23.59)	EGMQLDQLIQDTSLSRE
   84-   99 (25.87/21.42)	QPFDLDALGEAFQL.RE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15945 with Med19 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LREAAPVDLPHSEKGIPTVAGKSKSESKDKEKKHKKHKDKDKEKDKEHKKHKHRHRDRSKDKDKDKKRDKSVHHDSGADHSKKHHEKKRKHDGEEELNDVHKHKRSKHKSSKIDEIGAIKVAG
97
219










Molecular Recognition Features






MoRF SequenceStartStop




1) KDKEKKHKKHKDKDKEKDKEHKKHKHRHRDRSKDKDKDKKRDKSVHHDSGADHSKKHHEKKRKHDGEEELNDVHKHKRSK
2) SSKIDEIGAIKVAG
124
206
203
219