<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15921

Description Mediator of RNA polymerase II transcription subunit 8
SequenceMEGVVVGQDQQQQQQQQQQQAGRVMVEGLNPAVQQQLNLESVKTRAVSLFKAISRILEEFDAIARTNALPKWQDILGQFSMVNLELYNIVEDIKKVSKAFVVHPKNVNAENAAILPVMLSSKLLPEMEVEDNVKREQLLHSMQNLSVASQIEKLKVRIDMIGAACESAEKVIADTRKAYFGTRQGPTLLPTIDKAQAAKIQEQENLLRTAVNLGEGLRIPGDQRHITSGLPGHLVDVLAVADGPQSFADSSGTYLKNTPPFSSSNVNSQGALLQVSGALRAAASPSGTTSFDTTTASPLQHVNSPRSSANMMNTPSPQQQTHQQQQQQQXQQQQQQQQLQQLQQRQKMMQLPQHQQQLLAQQQLRQASIPGLGQLHGQPQMQFSQPLGAQQFQGRQLASGALHHGMGQSQLNQGNQLNRHLNQFSSPMNTALFNSAQSTPTSQMISNMSAMMPSQTLLPRMQIGMSGGTRNLAAANLSDQMFNMGGNNPGMMSIQQQQQQQHGTFANMSQNTQNLQQGMMPLQNTPQQTHPSFQQQRPQGQQ
Length542
PositionHead
OrganismCapsicum annuum (Capsicum pepper)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Solanoideae> Capsiceae> Capsicum.
Aromaticity0.04
Grand average of hydropathy-0.611
Instability index60.93
Isoelectric point9.30
Molecular weight59541.48
Publications
PubMed=29089032

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblPlants

GO - Biological Function
GO - Biological Process
defense response to fungus	GO:0050832	IEA:EnsemblPlants
regulation of flower development	GO:0009909	IEA:EnsemblPlants









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15921
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     618.75|     182|     314|       8|     220|       1
---------------------------------------------------------------------------
   16-  227 (241.73/156.05)	QQQQQAGRvMVEgLnPAVQQQLnLESVKTRAVSLFkAISRILEEFDAIARTNALPKWQ..DILG..QF.................................SMVNLELYNivedikkvsKAFVVHPKNVNAENAAILPvmlSSKLLPEMevednvkreqllhSMQNLSVASQIEKLKVRIDMIGAACESAEKVIADTRKAYF....GTRQGPTLLPTIDKAQAAKIQEQENLLRTAVNLGEGLrIP...GDQRHIT.
  228-  339 (142.05/59.10)	........................SGLPGHLVDVL.AVADGPQSF.ADSSGTYLKNTP........................................................................................................PFSSSNVNSQGALLQVSGALRAAASPSGTTSFDTTTASPLqhvnSPRSSANMMNTPSPQQQTHQQQQQQ...............qxqQQQQQQQL
  340-  530 (234.97/104.24)	QQLQQRQK.MMQ.L.PQHQQQL.LAQQQLRQASI...........PGLGQLHGQPQMQfsQPLGaqQFqgrqlasgalhhgmgqsqlnqgnqlnrhlnqfsSPMNTALFN.........SAQSTPTSQMISNMSAMMP...SQTLLPRM.............................QIGMSGGTRNLAAANLSDQMFNMG....G..NNPGMM.SIQQQQQQQHGTFANMSQNTQNLQQGM.MP..lQNTPQQTH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15921 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LLQVSGALRAAASPSGTTSFDTTTASPLQHVNSPRSSANMMNTPSPQQQTHQQQQQQQXQQQQQQQQLQQLQQRQKMMQLPQHQQQLLAQQQLRQASIPGLGQLHGQPQMQFSQPLGAQQFQGRQLASGALHHGMGQSQLNQGNQLNRHLNQFSSPMNTALFNSAQSTPTSQMISNMSAMMPSQTLLPRMQIGMSGGTRNLAAANLSDQMFNMGGNNPGMMSIQQQQQQQHGTFANMSQNTQNLQQGMMPLQNTPQQTHPSFQQQRPQGQQ
272
542










Molecular Recognition Features






MoRF SequenceStartStop




1) HKKIKHRD
2) TELWSRFFPE
66
102
73
111