<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15910

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMVDKLIVAVEGTAALGPYWKTILSDYLDKIIRSFFGAELTSQKSSAADVEVSLVVFNTHGSYSACLVQRSGWTRDMDTFFQWLSAIPFSGGGFNDAAVAEGLAEALMMFSSLNGNQSRQNMEGKRHCILISASNPYPLPTPVYRPQMQKLEQNENIEAQTDSRLSDAETVAKALPQCSISLSVICPKKLPKLRATYDAGKHNPRAADQPIDTAKNPNFLVLISENFIEARAAFSRSGMTNLTSNQSAVKMDVSSVPPVSGPQSISISAANVPAMSRSPISAGNIPPATVKIEPNTATSMAGPAFSHIPSVRPALQPVPSLQTSSPLSVSQEMASHTENVQEMKPIVMTQSLRPVAAAAVNVRILNDVAQARQALAGGTSIGLQSMGGTPMLSSMISSGMASSVPAQTVLSSGQSGVTTITGSVPLTGSGQNTQNSAPSSFTSTAPSMSGNSNISISQPLSNIQGGVSMAGQTVPGMSQGNLPGTQMMPSGTVMNQNVLTGMGATGLPSGTSTMMPAPGMSQQGQPGMQPVGVNSTAANMPLSQQQTSATLPSAQSKYVKVWEGNLSGQRQGQPVFITRLEGYRSASASESLAANWPPTMQIVRLISQDHMNNKQYVGKADFLVFRAMNQHGFLSQLQEKKLCAVIQLPSQTLLLSVSDKACRLIGMLFPGDMVVFKPQIPSQQQQQQPPPPQQLQAQHPQLQQQQQHLSQLQQQPLQQMQQQQQQPLMQLQHQQQIPLQQSQVPQMQQQHIHQLQQQQQQIPQMQQPQQQQPMVGTGMNQAYLQGPARSQLMTQGQVSSQGLPTMSGGSFIN
Length812
PositionUnknown
OrganismCapsicum annuum (Capsicum pepper)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Solanoideae> Capsiceae> Capsicum.
Aromaticity0.04
Grand average of hydropathy-0.299
Instability index64.21
Isoelectric point9.10
Molecular weight86898.83
Publications
PubMed=29089032

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15910
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     110.10|      16|      16|     697|     712|       1
---------------------------------------------------------------------------
  675-  690 (27.15/ 8.02)	FKP.QIP..SQQQQQQP.PP
  693-  709 (30.46/ 9.95)	QLQaQHP..QLQQQQQH.LS
  710-  728 (26.57/ 7.68)	QLQ.QQPlqQMQQQQQQpLM
  729-  744 (25.92/ 7.30)	QLQ.HQQ..QIPLQQSQ.VP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     360.59|      66|      70|     393|     458|       2
---------------------------------------------------------------------------
  236-  267 (39.09/ 9.35)	....SGM.........TNLTSNQS.....AVKMDVSSVP.........................PVSG...P.QSISIS..
  268-  330 (57.28/16.99)	.......AANVPAmsRSPISAGNI.....PPATVKIE.PNTATSMAGPafSHIPSvrPALQPVPSLQT...S.SPLSVSQ.
  393-  458 (113.88/40.74)	SMISSGMASSVPA..QTVLSSGQS.....GVTTITGSVPLTGSGQNTQ..NSAPS..SFTSTAPSMSG...N.SNISISQP
  460-  502 (62.14/19.02)	SNIQGGV..SMAG..QT....................VP....GM.SQ..GNLPG....TQMMPS..GtvmN.QNVLTGMG
  504-  573 (88.19/29.96)	TGLPSGTSTMMPA..PGMSQQGQPgmqpvGVNSTAANMPL..SQQQTS..ATLPS..AQSKYVKVWEG...NlSGQRQGQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.70|      16|      16|     745|     760|       3
---------------------------------------------------------------------------
  745-  760 (29.49/11.20)	QMQQQHIHQ.LQQQQQQ
  763-  779 (25.21/ 8.44)	QMQQPQQQQpMVGTGMN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.51|      17|      19|     632|     650|       6
---------------------------------------------------------------------------
  632-  650 (20.85/25.81)	FLSqLQEKKlCAVIQL..PSQ
  653-  671 (25.66/18.19)	LLS.VSDKA.CRLIGMlfPGD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15910 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LQQSQVPQMQQQHIHQLQQQQQQIPQMQQPQQQQPMVGTGMNQAYLQGPARSQLMTQGQVSSQGLPTMSGGSFIN
2) PQIPSQQQQQQPPPPQQLQAQHPQLQQQQQHLS
3) PSLQTSSPLSVSQEMASHTENVQEMKPIVM
4) QGGVSMAGQTVPGMSQGNLPGTQMMPSGTVMNQNVLTGMGATGLPSGTSTMMPAPGMSQQGQPGMQPVGVNSTAANMPLSQQQTSAT
5) SVPAQTVLSSGQSGVTTITGSVPLTGSGQNTQNSAPSSFTSTAPSMSGNSNISISQPLSN
738
677
318
463
402
812
709
347
549
461










Molecular Recognition Features






MoRF SequenceStartStop




NANANA