<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15869

Description 26S proteasome non-ATPase regulatory subunit 7-like protein B
SequenceMYLDDIETRSNLKDKNDDGSSNNDGHIFKIFSKSVKLYKDGYSDVISKKDFYMAQWYVFNNCEEAEPFVEEHKEELLKQGVEDIEEKHREQFPSWFRKKIMQLFNKEKSRSIMKVNPLTMGPDVCGEKSTSCIVNGVRYHIQQHDELCKSQNCGIVVRDLHEKVDIDFYGTITDILELKYVEENSVFLFKCKWFDLLDMLNQLHRDDVEPITIGANVIELEAQIEYKVEVDYDEKDSDQEDDTMRYFFIIALLYLNLEDEVLIEEGGLQTHTLSGVKSVYALPFPDPTYGIALGPRELTGVVDLITYFKLLPHQEFFCKKPFPLLILDTHYLYNVVGDTDIRKGQGMQLDQLIQHTSSVKETNLGIQPFDLDALREAFQLCEKAPIDLPPSKKGIPIIAGKSKSESKDNEKNLSHELCVFYDGKSGSRDSIKMKANAESKQISSKPIEKVIVHPLVLLSIVDHYNRVARDTRKYVVGVFLGTSFKDTVDVTDSYAVPFEEDNRDPILVIIDVQPEELGIPTKVYDVVEKVKENATQQIQNVLVHVPL
Length547
PositionHead
OrganismCapsicum annuum (Capsicum pepper)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Solanoideae> Capsiceae> Capsicum.
Aromaticity0.09
Grand average of hydropathy-0.384
Instability index36.88
Isoelectric point4.96
Molecular weight62760.68
Publications
PubMed=29089032

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
proteasome complex	GO:0000502	IEA:UniProtKB-KW
GO - Biological Function
isopeptidase activity	GO:0070122	IEA:InterPro
metallopeptidase activity	GO:0008237	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro
transcription factor binding	GO:0008134	IBA:GO_Central
GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP15869
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     525.47|     144|     291|      93|     243|       1
---------------------------------------------------------------------------
   93-  243 (230.84/188.69)	PSwfRKKIMQLFNKEKSRSiMKVNPLTMGPDVC...GEKS..TSCIVNGVRYHIQQHDELCKSQNC.GIVV..RDLHEKVDIDFYGTITDILELKYVEeNSVFL...FKCKW.FDLL........................DMLN.QLHRDDVEPITIGANVIELEAQIEYKVevdYDEKDSDQEDDT
  250-  373 (97.51/62.72)	....................IALLYLNLEDEVL...IEEGglQTHTLSGVK...SVYALPFPDPTY.GIALgpRELTGVVDL.....ITYFKLLPHQE.........FFCKKpFPLLildthylynvvgdtdirkgqgmqlDQLI.Q.HTSSVKETNLGIQPFDLDA.....................
  390-  535 (197.12/138.73)	PS..KKGIPIIAGKSKSES..KDNEKNLSHELCvfyDGKS..GSR..DSIKMKANAESKQISSKPIeKVIV..HPLVLLSIVDHYNRVARDTR.KYV..VGVFLgtsFK.DT.VDVT........................DSYAvPFEEDNRDPILVIIDVQPEELGIPTKV...YDVVEKVKENAT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.06|      14|      37|      36|      49|       2
---------------------------------------------------------------------------
   36-   49 (23.79/15.04)	KLYKDGYSDVISKK
   75-   88 (23.27/14.55)	ELLKQGVEDIEEKH
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP15869 with Med19 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
NANANA

Molecular Recognition Features

MoRF SequenceStartStop
1) HIFKIF
26
31