<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15827
Description |
Mediator of RNA polymerase II transcription subunit 20 |
Sequence | MPSPWPLTMPLPRPCHPNAIACAMSSPLLRHCLDHVMSMPSPVPCHCLGYATVVRIDSILQWRPNAGTTLSTQILSEVSQCIETINGVKEGRWKNTVCFYRPILKDQAKAVEFPKDFKGISLQEQPDMYYMIIRQQRLIMEAESSMQEIMEKLQSYKTRIAISFEGFQYRLGDFRLRVGKVSPVNSENLRGIMMEMEYLPISSWETSPQIMNEFFDILKETLEGRSLPGHFVHVEPNFSEYGLSDQYTSQHTAVQYASFMAQMISTVNDAEKDSDIDPQEAHQTLEIAEAENLMTSVPKAKKEEQEQEFVLSNQSSGFPLLSRPSSSSTTTVVVANGHPPFRKVTRPAFRSKVVYHCYGADRFTTSAPLSDIGTLFKLIHRWRKREH |
Length | 387 |
Position | Head |
Organism | Capsicum baccatum (Peruvian pepper) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae>
asterids> lamiids> Solanales> Solanaceae> Solanoideae> Capsiceae> Capsicum.
|
Aromaticity | 0.09 |
Grand average of hydropathy | -0.369 |
Instability index | 61.65 |
Isoelectric point | 6.47 |
Molecular weight | 44091.02 |
Publications | PubMed=29089032
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364152
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP15827
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 71.59| 13| 28| 7| 22| 1
---------------------------------------------------------------------------
7- 22 (25.40/21.95) LTMPLPRPCHPNaiaC
24- 35 (19.05/ 7.70) MSSPLLRHCLDH....
37- 47 (27.14/15.31) MSMPSPVPCH.....C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 67.22| 19| 22| 310| 328| 2
---------------------------------------------------------------------------
310- 328 (32.27/19.50) VLSNQSSGFPLLSRPSSSS
333- 351 (34.95/21.70) VVANGHPPFRKVTRPAFRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 94.57| 28| 28| 56| 83| 3
---------------------------------------------------------------------------
56- 83 (46.53/33.63) IDSILQWRPNAGTTLSTQILSEVSQCIE
85- 112 (48.04/34.95) INGVKEGRWKNTVCFYRPILKDQAKAVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 44.99| 15| 27| 262| 280| 5
---------------------------------------------------------------------------
262- 280 (20.18/19.84) QMISTVNDAEKdsdiDPQE
292- 306 (24.81/13.52) NLMTSVPKAKK....EEQE
---------------------------------------------------------------------------
|