<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15754
Description |
Related to RNA polymerase II holoenzyme/mediator subunit |
Sequence | MADRLTQLQDCIDVLNTLMFASLNYVHTRHPYGEIPGQPSQAPHPSGQENGTANGDAQQGEGQTGSHEAGAPTPEEQRVFNAALREMAQDVVLQEQQIEIIVNQLPGIGSSEADQERRMRELEVEMREIEEQRAKKETEREKMVDMLGEIIGRVKRVP |
Length | 158 |
Position | Middle |
Organism | Ramularia collo-cygni |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Dothideomycetidae> Mycosphaerellales> Mycosphaerellaceae> Ramularia.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.796 |
Instability index | 54.36 |
Isoelectric point | 4.75 |
Molecular weight | 17687.52 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 ARBA:ARBA00003669
ECO:0000256 RuleBase:RU366036
|
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP15754
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 123.85| 38| 53| 48| 86| 1
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48- 86 (60.84/34.83) QENGTANGDAQQgEGQTGSHEAGAPTPEEQRVFNAALRE
104- 141 (63.01/32.13) QLPGIGSSEADQ.ERRMRELEVEMREIEEQRAKKETERE
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