Description | Mediator of RNA polymerase II transcription subunit 9 |
Sequence | MATPVSVVDETEDYSFLPLIHDIIKCMDKDNQDVHQELNKLRTRIQDTREQILAMPGIDLSSEVQQHKLRTLREQVRTKNQLLQKYKGLCMFDIPKPS |
Length | 98 |
Position | Middle |
Organism | Ictalurus punctatus (Channel catfish) (Silurus punctatus) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Ostariophysi> Siluriformes> Ictaluridae> Ictalurus. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.629 |
Instability index | 54.74 |
Isoelectric point | 6.27 |
Molecular weight | 11465.10 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364145 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP15730 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 55.02| 18| 28| 35| 53| 1 --------------------------------------------------------------------------- 35- 53 (25.45/25.43) HQELNKLRTRIQdTREQIL 66- 83 (29.57/23.13) QHKLRTLREQVR.TKNQLL --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) DVHQELNKLRTRIQDTREQILAMPGIDL 2) MATPVSVVDETEDYSFLPLIHDIIKCM 3) QQHKLRTLREQVRTKNQLLQKYKGLCMFDIPKPS | 33 1 65 | 60 27 98 |
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