<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15702

Description mediator of RNA polymerase II transcription subunit 23 isoform X2
SequenceMAVPMETQLQSIFEDVVKTEVIEEAFAGMFMDTPEDERTKLISCLGAFRQYWGSLPQESHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETNLLPPKMVCQALIGSETLEWERAQLWSLTFKLIRKIIGGVDYKGVRDLLKAVLDKMQTIPNLVSSAVVQQLLPAREVVEYILDRNACLLPAYFAVTEIRKLYPEGQLSHWLLGSLISDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLRGMLPYDKDLFEPQTGLLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEEQLVDLVVYAMERSETEEQFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKSLPMTDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGTVRIPLPGTNCTASCSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSIALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHITDFFTGSDSIQGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGFSSSIGGLRSCRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENAPEHWLQSDWHTKHMSYHKKYPEKLYFEGLAEQVNPPMQLQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRDRTNLKRKLVHAIMSSLKDNRTPGWCLSETYLKFGMNPREDNVWVPDDTYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGGDVGNALLNVVLRSQPLVPRENVTAWMNAIGLIITALPEPYWIVLHDRIVSVIGSPALTSDAEWVGYPFQLLDFTACHQSYSEMYCSYVLALAHAVWHHSSIGQLSLIPKFLSEVLKPLVKTEYQLLYIYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDHHSNHLAYMDPICDFLYHIKYMFTGDSVKDQVEKIICTLRPAMKLRLRFITHTSKMEPAAAVATATSASQPTTVSSPAPQTGTGPSSIPLSVPQ
Length1390
PositionTail
OrganismIctalurus punctatus (Channel catfish) (Silurus punctatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Ostariophysi> Siluriformes> Ictaluridae> Ictalurus.
Aromaticity0.10
Grand average of hydropathy-0.019
Instability index47.15
Isoelectric point7.10
Molecular weight158426.17
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15702
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.19|      34|      66|      90|     155|       1
---------------------------------------------------------------------------
   90-  129 (52.58/94.77)	AVETNLLPPKMVCQALIGSEtlewerAQLWSLTFKL..IRKI
  159-  194 (52.61/24.49)	AVVQQLLPAREVVEYILDRN......ACLLPAYFAVteIRKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.80|      19|      66|    1227|    1245|       2
---------------------------------------------------------------------------
 1227- 1245 (36.98/20.34)	HAVWHHSS.IGQLSLIPKFL
 1293- 1312 (32.82/17.29)	QAVDHHSNhLAYMDPICDFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.27|      15|      15|    1009|    1023|       3
---------------------------------------------------------------------------
 1009- 1023 (28.73/16.50)	YKFHDRPVTYLYNTL
 1026- 1040 (26.54/14.72)	YERHLRDRTNLKRKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.19|      13|      17|     261|     273|       6
---------------------------------------------------------------------------
  261-  273 (25.15/16.66)	PYDKDLFEPQTGL
  281-  293 (26.04/17.54)	PYSRDMVCNMLGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.72|      15|      21|    1045|    1062|       8
---------------------------------------------------------------------------
 1045- 1062 (24.63/23.94)	MSSLKDNrtpGWCLSETY
 1067- 1081 (31.09/19.55)	MNPREDN...VWVPDDTY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.77|      11|      21|     936|     948|       9
---------------------------------------------------------------------------
  936-  948 (18.61/17.07)	MSYHKKY.PekLYF
  959-  970 (19.16/10.05)	MQLQPQYlP..IYF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.82|      12|      17|     355|     366|      12
---------------------------------------------------------------------------
  355-  366 (21.06/11.80)	HMVLSLHQKLAG
  375-  386 (22.76/13.35)	HLMWVLLQFISG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.13|      40|     629|     700|     741|      13
---------------------------------------------------------------------------
  700-  741 (70.12/54.93)	HITDFFTGsDSIQGTWCKDI..LQTIMNFTpHNWASHTLSCFPA
 1314- 1355 (67.01/42.76)	HIKYMFTG.DSVKDQVEKIIctLRPAMKLR.LRFITHTSKMEPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.28|      25|     629|     462|     496|      14
---------------------------------------------------------------------------
  462-  496 (31.03/48.56)	LQQSLRnKSLPMTDykiallCNAystNSECFTLPM
  505-  529 (48.24/33.68)	GNGTVR.IPLPGTN......CTA...SCSITPLPM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.91|      24|     580|      38|      65|      15
---------------------------------------------------------------------------
   38-   65 (38.53/36.85)	RTKLISCLGAFrqywGSLPQESHEQ...CVQ
  624-  650 (37.38/22.95)	RVQLLSHLHSL....AAVPQTNQNQlhlCVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      88.85|      19|      85|     778|     796|      16
---------------------------------------------------------------------------
  778-  796 (34.60/17.32)	NDIITHFSMQGSPPLFLCL
  808-  822 (23.05/ 9.40)	NQIGFSSSIGG...LRSC.
  865-  883 (31.20/14.98)	NDMVWKYNIVTLDRLILCL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.27|      20|      89|    1085|    1106|      17
---------------------------------------------------------------------------
 1085- 1106 (32.22/27.99)	LIGRLVDTMaGkSPGPFPNCDW
 1163- 1175 (19.69/ 8.29)	.IGLIITAL....PEPY....W
 1178- 1197 (34.35/20.11)	LHDRIVSVI.G.SPALTSDAEW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.14|      11|      17|     412|     422|      19
---------------------------------------------------------------------------
  412-  422 (22.11/13.90)	CIPVPDINKPQ
  431-  441 (22.04/13.83)	CIWIHLNRKAQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15702 with Med23 domain of Kingdom Metazoa
Unable to open file!