<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15701

Description mediator of RNA polymerase II transcription subunit 23 isoform X4
SequenceMAVPMETQLQSIFEDVVKTEVIEEAFAGMFMDTPEDERTKLISCLGAFRQYWGSLPQESHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETNLLPPKMVCQALIGSETLEWERAQLWSLTFKLIRKIIGGVDYKGVRDLLKAVLDKMQTIPNLVSSAVVQQLLPAREVVEYILDRNACLLPAYFAVTEIRKLYPEGQLSHWLLGSLISDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLRGMLPYDKDLFEPQTGLLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEEQLVDLVVYAMERSETEEQFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKSLPMTDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGTVRIPLPGTNCTASCSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSIALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHITDFFTGSDSIQGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGFRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENAPEHWLQSDWHTKHMSYHKKYPEKLYFEGLAEQVNPPMQLQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRDRTNLKRKLVHAIMSSLKDNRTPGWCLSETYLKFGMNPREDNVWVPDDTYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGGDVGNALLNVVLRSQPLVPRENVTAWMNAIGLIITALPEPYWIVLHDRIVSVIGSPALTSDAEWVGYPFQLLDFTACHQSYSEMYCSYVLALAHAVWHHSSIGQLSLIPKFLSEVLKPLVKTEYQLLYIYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDHHSNHLAYMDPICDFLYHIKYMFTGDSVKDQVEKIICTLRPAMKLRLRFITHTSKMEPAAAVATATSASQPTTVSSPAPQTGTGPSSIPLSVPQ
Length1380
PositionTail
OrganismIctalurus punctatus (Channel catfish) (Silurus punctatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Ostariophysi> Siluriformes> Ictaluridae> Ictalurus.
Aromaticity0.10
Grand average of hydropathy-0.021
Instability index46.36
Isoelectric point7.01
Molecular weight157478.12
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15701
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.27|      15|      15|     999|    1013|       1
---------------------------------------------------------------------------
  999- 1013 (28.73/18.79)	YKFHDRPVTYLYNTL
 1016- 1030 (26.54/16.78)	YERHLRDRTNLKRKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.19|      13|      17|     261|     273|       2
---------------------------------------------------------------------------
  261-  273 (25.15/16.98)	PYDKDLFEPQTGL
  281-  293 (26.04/17.87)	PYSRDMVCNMLGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.19|      34|      66|      90|     155|       3
---------------------------------------------------------------------------
   90-  129 (52.58/90.84)	AVETNLLPPKMVCQALIGSEtlewerAQLWSLTFKL..IRKI
  159-  194 (52.61/23.39)	AVVQQLLPAREVVEYILDRN......ACLLPAYFAVteIRKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.80|      19|      66|    1217|    1235|       4
---------------------------------------------------------------------------
 1217- 1235 (36.98/27.47)	HAVWHHSS.IGQLSLIPKFL
 1283- 1302 (32.82/23.39)	QAVDHHSNhLAYMDPICDFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.72|      15|      20|    1035|    1052|       5
---------------------------------------------------------------------------
 1035- 1052 (24.63/22.40)	MSSLKDNrtpGWCLSETY
 1057- 1071 (31.09/18.31)	MNPREDN...VWVPDDTY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.77|      11|      21|     926|     938|      11
---------------------------------------------------------------------------
  926-  938 (18.61/19.44)	MSYHKKY.PekLYF
  949-  960 (19.16/11.52)	MQLQPQYlP..IYF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.82|      12|      20|     355|     366|      13
---------------------------------------------------------------------------
  355-  366 (21.06/13.82)	HMVLSLHQKLAG
  375-  386 (22.76/15.65)	HLMWVLLQFISG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.14|      11|      20|     412|     422|      14
---------------------------------------------------------------------------
  412-  422 (22.11/14.71)	CIPVPDINKPQ
  431-  441 (22.04/14.63)	CIWIHLNRKAQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15701 with Med23 domain of Kingdom Metazoa
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