<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15659
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MDGKIEISLDKLPVKRLEAIEENGVERFPTDIGYDEKRVSLIRRIDFAWAVEKEDEEKKKKQKKSSKESSSTPWPWQSMVENLQLALQELSVVIDLINTVEANDAVTVASMTRPKPLPNEHLADLAVSTATKLQCYRHLGKYFKQSAKALEQQVAREARFYGALIRLQQNWKVKRQRMAATGPSNEGFTIDLFDNSLYDSASLFRPSSLSTIHIDHDSAGMLAINLPPTSCRSLRFGFVGVHSSENVKKSTKIRSSGSDELPSKGTERESGSDNECVKETNLLLREVHRAIFDEQVFDMVNREAFNQSLGVNVTGIQENYLQLSISPGISVCITLVPSYEYDQTVDDGGCQISESAVLPLDSLDGVKLPEEKHECVNKKSSIPNHMSCEIYLQQIFHEHVFVRAKDRHLSSGTRVPGQPPPKDGSGLLGHFCMSVAHRIFSNRALMELENVVCKVPYLHLVSHPTWNSRISSWTVLMKVPQSIIHASSQSRTSDAKSKSDIKTEFRTKIVVNDGRINVEAEGAPNVVSLFKGSSDDICSINKYDCDLVDLPVIILQQVASQVIRWLHEEALMVGIKANRDFLCLSLELEQGEVLSLVAHVDAEDAEGCISWWLVMEDGFAEEKKLHMDITNGASEYRKFLGYLPLDVLYSTLMDLVSLCNGGGSQ |
Length | 665 |
Position | Head |
Organism | Manihot esculenta (Cassava) (Jatropha manihot) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae>
rosids> fabids> Malpighiales> Euphorbiaceae> Crotonoideae> Manihoteae>
Manihot.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.300 |
Instability index | 47.18 |
Isoelectric point | 5.65 |
Molecular weight | 74300.61 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | core mediator complex GO:0070847 IBA:GO_Central
mediator complex GO:0016592 IBA:GO_Central
|
GO - Biological Function | transcription coregulator activity GO:0003712 IBA:GO_Central
|
GO - Biological Process | production of miRNAs involved in gene silencing by miRNA GO:0035196 IEA:EnsemblPlants
regulation of transcription by RNA polymerase II GO:0006357 IBA:GO_Central
|
Interaction
Repeat regions
Repeats |
>MDP15659
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 149.38| 46| 98| 252| 297| 1
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252- 297 (77.40/48.45) KIRSSGSDELPSKGTERESGSDNECVKET....NLLLREVH.RAIFDEQVF
351- 401 (71.98/44.57) QISESAVLPLDSLDGVKLPEEKHECVNKKssipNHMSCEIYlQQIFHEHVF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 83.00| 25| 325| 185| 236| 2
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94- 122 (39.22/10.74) IDLINtveaNDAVTVASMTRPKPLPNEHL
190- 214 (43.78/51.27) IDLFD....NSLYDSASLFRPSSLSTIHI
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