<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15646

Description Uncharacterized protein
SequenceMGDGNATTNNRSVSNSNNNEKPEWLQQYNLIGKIGEGTYGLVFLAKTKSPANRGKSIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLVNVHINHADMSLYLAFDYAEHDLYEIIRHHRDKGSHCINQYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGEGDEHGVVKIADFGLARIYQAPLKPLSDNGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSTPNPFQLDQLDKIFKVLGHPTLEKWPTLANLPHWQSDLQHIQGHKYENTGLHNVVHLSPKSAPYDLLSKMLEYDPRKRITAAQALEHEYFRIEPLPGRNALVPSQPGEKVINYPTRPVDTNTDFEGTTSLQPPQPVSSGNAVSGGMPGGHGVANRSASRPMQIGMPRMQPQVMATYNMAQAGMGGAMNPAGIPMPRGVAAQPHQQQHLRRKDPPGMGSGYPPQQKSRRQ
Length477
PositionKinase
OrganismManihot esculenta (Cassava) (Jatropha manihot)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Malpighiales> Euphorbiaceae> Crotonoideae> Manihoteae> Manihot.
Aromaticity0.07
Grand average of hydropathy-0.491
Instability index39.63
Isoelectric point9.24
Molecular weight52995.88
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central

GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15646
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     149.22|      38|      40|     379|     418|       1
---------------------------------------------------------------------------
  343-  383 (55.32/23.37)	LPGRNALVPSQPGEK.VINY.PTRPVD...TN...TDF...........egttslQPPQP
  384-  418 (47.97/26.19)	VSSGNAVSGGMPGGHgVANRsASRPMQIGMPR...MQP......................
  421-  472 (45.93/18.38)	MATYNMAQAGM.GG.......AMNPAGIPMPRgvaAQPhqqqhlrrkdppgmgsgYPPQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.73|      28|      44|     166|     195|       2
---------------------------------------------------------------------------
  166-  195 (44.47/44.03)	LVMGEGDEHGVVKIADFGLarIYQA..PLKPL
  211-  240 (45.26/36.70)	LLLGAKHYTSAVDMWAVGC..IFAEllTLKPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.15|      32|      47|     242|     274|       3
---------------------------------------------------------------------------
  242-  274 (52.35/35.39)	QGAEAKST..PNPFQLDQLDKIFKVLGHpTLEKWP
  290-  323 (52.80/30.73)	QGHKYENTglHNVVHLSPKSAPYDLLSK.MLEYDP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15646 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LPGRNALVPSQPGEKVINYPTRPVDTNTDFEGTTSLQPPQPVSSGNAVSGGMPGGHGVANRSASRPMQIGMPRMQPQVMATYNMAQAGMGGAMNPAGIPMPRGVAAQPHQQQHLRRKDPPGMGSGYPPQQKSRRQ
343
477










Molecular Recognition Features






MoRF SequenceStartStop




1) GVAAQPHQQQHLRRKDPPGMGSGYPPQQKSRRQ
2) RGKSIAIKKFKQ
445
53
477
64