<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15602

Description Uncharacterized protein
SequenceMPLTPSQIKDKLINALDNDKNIIDEKAVEEVITLLEASNITKEILEQTRLGRDINDIRKTSKNPVIAKRAKNLVKSWKKLITPVANGQHPAQKISPGLSPAVSISNATAKNLPSPALINARQQALKAAGPVRSPIVQPKANQQVLPTSKLAQPEAKLKQGTDKKSPMPAAIRQSQRHGNNCVNDDSNFSWPGTPPSTISDSSQDRLIGDRENQDSSSAGNRGQRTVPDKRNFNFDNSHLVHSAESTAKSLNRASDQREVSKTNIANRKRARPSEFDDSNDSSVYIPSSKQPHLVSSSPSLSTFNRNDVINGTVKKKSIKSPGVNARDNVATDFKTMVSSSSRNSLNDQSDASMSFNRSQQKFAALRQDSVDSRISVQSSDSRRIKEKHSKVKTTEQLLEDMQKRLATTVDTNVIAQLRTNQMKKDTDTQKIVLPSGSKHRGRKKKQDRGLPDTESASDGRKLAQTKNEYIERFLLTSVAPVPGEDAFEHSLPSRQDSLDEHHINLGGCSSSFSQSVYDPGFSYSGRQDKPDSGPSASPPEARDISEVMGSLPSTSASLESSVRLSEEQVLARLPPIDYGNIDWTMHDYPAPQELPVTAGLVDRLHKDNIPGLNGTYDFVGQFKKWHETLTLDTVNGEPLYILPYVIPND
Length649
PositionUnknown
OrganismBiomphalaria glabrata (Bloodfluke planorb) (Freshwater snail)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Gastropoda> Heterobranchia> Euthyneura> Panpulmonata> Hygrophila> Lymnaeoidea> Planorbidae> Biomphalaria.
Aromaticity0.04
Grand average of hydropathy-0.797
Instability index55.21
Isoelectric point9.29
Molecular weight71384.75
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15602
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     160.93|      49|      68|      62|     111|       1
---------------------------------------------------------------------------
   62-  111 (77.09/45.14)	KNPVIAKRAKNLVKSWKKLITPVANGQHPAQKISPgLSPAVSISNATAKN
  132-  180 (83.84/45.22)	RSPIVQPKANQQVLPTSKLAQPEAKLKQGTDKKSP.MPAAIRQSQRHGNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.06|      40|      43|     187|     227|       2
---------------------------------------------------------------------------
  187-  206 (25.10/ 7.14)	...........................NFS...WPGT.PPSTISDSSQDRL
  207-  250 (55.22/27.04)	IGDRENQDSSSAGNRgQRTVP...dkrNFN...FDNS.HLVHSAESTAKSL
  253-  297 (36.74/13.59)	ASDQREVSKTNIANR.KRARPsefddsNDSsvyIPSSkQPHLVS.SS....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     248.61|      63|      99|     434|     496|       3
---------------------------------------------------------------------------
  352-  410 (58.33/24.48)	.SMSFNRSQQKfaalRQDS...................VDSRisvQSSDSRRIKEkhSKVKTTEQLL..........E.D.MQKRLATTVD
  434-  496 (109.98/51.37)	PSGSKHRGRKK....KQDRG.................LPDTE...SASDGRKLAQ..TKNEYIERFLLTSVAPVP.GE.DAFEHSLPSRQD
  518-  593 (80.31/35.92)	DPGFSYSGRQD....KPDSGpsasppeardisevmgsLPST....SAS.....LE..SSVRLSEEQVLARLPPIDyGNiDWTMHDYPAPQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.31|      21|      31|       3|      23|       5
---------------------------------------------------------------------------
    3-   23 (34.44/24.62)	LTPSQIKDKLINA..LDNDKNII
   35-   57 (28.88/19.43)	LEASNITKEILEQtrLGRDINDI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15602 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKNLPSPALINARQQALKAAGPVRSPIVQPKANQQVLPTSKLAQPEAKLKQGTDKKSPMPAAIRQSQRHGNNCVNDDSNFSWPGTPPSTISDSSQDRLIGDRENQDSSSAGNRGQRTVPDKRNFNFDNSHLVHSAESTAKSLNRASDQREVSKTNIANRKRARPSEFDDSNDSSVYIPSSKQPHLVSSSPSLSTFNRNDVINGTVKKKSIKSPGVNARDNVATDFKTMVSSSSRNSLNDQSDASMSFNRSQQKFAALRQDSVDSRISVQSSDSRRIKEKHSKVKTTEQLLEDMQKRL
2) PGFSYSGRQDKPDSGPSASPPEARDISEVMGS
3) TVDTNVIAQLRTNQMKKDTDTQKIVLPSGSKHRGRKKKQDRGLPDTESASDGRKLA
109
519
408
405
550
463










Molecular Recognition Features






MoRF SequenceStartStop




1) LVKSWKKL
73
80