<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15596

Description Uncharacterized protein
SequenceMATAFPSQEHTPIKKPRLGPPDVYPQDPKQKEDELTQQNVKHGFQLGTVVTDECASAKDIEITLEKCSTFYNSVLKKKNELNTLQDSKNKKFQLPVKEHFWPAACSKPSTEAWFKDLAGSKPLASLSRKVPTFNKKEEIFSTLCEYAVPNVRAAWFIKMTAAHNMGTQDSRNRRKLTVDQFMDWTQAISKYLKDQLQKIQDFYHGTSGATATPFLLAPSPATSQVDLDLAMKNWNYCTRFANHLYEEGLLDRHDFLNWLIELPDKMKQTDDVVLKLILVQMNIYSSDMCKSVILVRRLANYCGRKISHLVAEMDHMLGRTDPQMSANGTPLTPAQAINTTIQMCNPLINAMAEFKECQSHRFIVLQLCALAQIITIKCPTAMVWNSLGDYKSNSYLVGSPLDLYPCATSSLPMPPGQSNTYIRQQVKNAEQQIIARSHSAEVHWSSDKCQQSAVGYIMSKVLKVLDVLDQHNFDIVDSIYNMDSLYTKIFSITQSKETGEAPIGDEPIINLLVDWAVSVQRVGDHRCIVVALLLERRQNEIRSEKFGEVESGDDKDGVHSETLTSTPVFQSLLMSFLDTRAPVLEEHPTDEAKQAFKNLISLFNELIVHDVFSHDAYMHMLISRGDLGLAPAYTAPLADQDDLFSTKSPPESIKHEVTLGDDEIKVDMDIHTMEENFGSLFGSMKEESKPSPEPPAIDLNLGSLNASVKSIKSEKEQPLGSVGDFSTTPAAPAPPKGPSRHMVYATHFPIPQDDCSSHEINQRMIVLYGVGKARDEARHMFKKISKEIVKLFSKRNCIDVTSGDLGKVKKKKEKEAKEAETNATPSTLNTTVTSPNFDNLQQKFSKLSYFDQHQVTAQCTSAVLDQIKSFTAGNSSYLPLGDNISFLFDLMQSALNINGLLEFIIRILKDLVEVEKELHQKESFLMMTYTTDVCLNIVAVLRRYHSYLLSPQGLSSELFIGLTDILKVVNVCNPIYCSTAERCVLTYLYDIYSTCSPLQMRHSEIFNPAYTKMKATLFAQITPSSTNAKWDQNEMTDIIKSARLPDEPHKLHKSLADCATTRYSFVCNVLLHVVSTSAENLRTINDLAVLCAELTAHCNSLSPEWLGVLKALCCSSQQDLGFIDVLTTIDVSDLSIHDSLAVFTAMLIARHCFSLQDFVYHVALPSLMAVCCPEEGDAEAESGARLSCHLLLRLFKPSYLIAPQCSISQKNPPPIRNSCDRHLLEAAHLFIGVGPMLAVLKAMLKLADESNDESTSKGSSGNSKDKTGMFLDYMLRNLETDGISAEMEAMLSASSGGQSGKDGLGSGSLSEFAKCALTEICRQDWVREKFLRNPEKLFTSDLLNDPILSYRQAQQLLQLICYPTGVPNQVEGCEPENKHVVQRVLQTLDQWTLRVSWLELQLLFERAQSVAETNSLLELVSRGTIDLFDQLTENKNTSESSSVSITSENKSNIENTIWLVAPLIAKLPSTIQGRVLKLAAAVLEQSINEYSSAKNKQEKEKEKNIRSKTLLGHQPFLSLVLSCLKGQDEQREFLLRSLLNQMEMLISNFKDYTENKGLEEGKIRQSIQECIHLRLSLVGGIFDVIQRNNASTSDWALILVQLVSHDMIDCQSNSELFLTVVDMLTVLIHGTLLSEGQEKGDENRKPYFNLIKKLRKELGDKNNPTIDQVRQLFPLPKKQCEVITVEPYGAVLDNKGNRVQGFDAIGKKPGLQVAQKVVFNPWEIIEGHKNMPPIPWSYFGAVRLEKKTLKYEEQKRLDLYHSHCLRKPLSYYLEPPNLPPEDLEPIPEKHDEKPREHIEHSLDLKKTVNNKKKKRPAKPAPPSNFPNIVSHDITLVFWYLS
Length1841
PositionKinase
OrganismBiomphalaria glabrata (Bloodfluke planorb) (Freshwater snail)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Gastropoda> Heterobranchia> Euthyneura> Panpulmonata> Hygrophila> Lymnaeoidea> Planorbidae> Biomphalaria.
Aromaticity0.07
Grand average of hydropathy-0.301
Instability index43.96
Isoelectric point6.06
Molecular weight206787.51
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15596
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.40|      36|      41|    1079|    1119|       1
---------------------------------------------------------------------------
 1084- 1119 (68.63/49.76)	I..............NDLAVLCAELTA.HCNSLSPEWLGV....LKALCCSSQQD
 1123- 1177 (49.77/24.89)	IdvlttidvsdlsihDSLAVFTAMLIArHCFSLQDFVYHValpsLMAVCCPEEGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     133.84|      41|      41|     650|     690|       2
---------------------------------------------------------------------------
  650-  690 (70.23/52.40)	PESIKHEVTLGDDEIKVDMDIHTMEENFGSL..FGSMKEESKP
  692-  734 (63.61/46.61)	PEPPAIDLNLGSLNASVKSIKSEKEQPLGSVgdFSTTPAAPAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     156.82|      48|     688|     989|    1055|       3
---------------------------------------------------------------------------
  989- 1047 (78.88/87.79)	YDIYSTCSPLQMRHSEIFNPAYTKM..KATLFAQITPsstnakwdqneMTDIIKSA.RLPDE
 1199- 1249 (77.94/46.44)	YLIAPQCSISQKNPPPIRNSCDRHLleAAHLFIGVGP...........MLAVLKAMlKLADE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.11|      18|      41|      97|     114|       4
---------------------------------------------------------------------------
   97-  114 (37.07/21.46)	KEHFWPAACSKPSTE...AWF
  136-  156 (29.04/15.23)	KEEIFSTLCEYAVPNvraAWF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     229.71|      92|     688|     179|     293|       5
---------------------------------------------------------------------------
  190-  248 (64.97/74.51)	.............................................................................................................................................................................................................................................KYLKDQLQKIQDFYHGTSGATATPFLLAPsPATSQVDLD.....lamknwNYCTRFANHLYEE..G
  249-  315 (82.44/62.05)	LLDRHDFLNWLIELPDKMKQTDDVVLKLILVQMNIYSSDM............................................................................................................................................................................................................................................cksvilvrrlaNYCGRKISHLVAEmdH
 1510- 1549 (41.63/15.51)	LLGHQPFLSLVLSCLKGQDEQREFLLRSLLNQMEMLISNF.......................................................................................................................................................................................................................................................................
 1747- 1784 (40.66/15.07)	........................................kdytenkgleegkirqsiqecihlrlslvggifdviqrnnastsdwalilvqlvshdmidcqsnselfltvvdmltvlihgtllsegqekgdenrkpyfnlikklrkelgdknnptidqvrqlfplpkkqcevitvepygavldnkgnrvqgfdaigkkpglqvaqkvvfnpweiieghknmppipwsyfgavrlekKTLKYEEQKRLDLYHSHCLRKPLSYYLEP.PNLPPEDLE...........................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.27|      17|    1050|     590|     606|       7
---------------------------------------------------------------------------
  590-  606 (29.01/18.89)	DEAKQAFKNLI.SLFNEL
 1641- 1658 (26.26/16.34)	DENRKPYFNLIkKLRKEL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15596 with Med12 domain of Kingdom Metazoa
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