<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15584

Description Uncharacterized protein
SequenceMAAETGIPSVYLEHQLSHGRAAKRTQESFIDRLKHKNSQNRSWNDSIKIVKSSVAELRQQPDVIEDASVQKCLDTIQKAMKVISQQTLKERLDSIGRQLGMSTSIQEQKVSLSSDAFHVDVLLDGDNITSVKLANQGDVVDCPDLKDILRKGDFSEFIEHLQGLQSIYQVTNDEKLKSKAFLALQALEKDLNQLSQFQSSISGVANYIHKCPLGIMLPRLAGKPMKLIYFVSPYDLLDKKSLTAHPLTVEAITENFLGQSVTVCLEPVPDSASPNKLQTMPLMNVSKTQEGKSLPSFSAVTKINSMMLPASFVLVLPQPLPISMQLLQKITMLTNLEIHQVTECKSLCSLVLETYSDGKIQDCRKLFVSLPDQRHIYFLDGLNGVSQDLQGVMVSRIPFTHPTHVPQILNLLRQQLLFNIVLSSCIRPASKKEVLNTIVFEVTTVSLQQLTIVFEHPAYDSMITVDIDLTDITNLKCHITCTNPEHTLCTDDALSKVFQRCMSIPIMLRWLVGIGRHHLDKLKEAAALAAEKEKNDNALFLKELKQRQAKLQATMPTKGRPPPQPPHPTLPPPPSYTQIHYSVAPTHSHMSSNGQSQMVPMLLDSRTATEGMEDYRNFSDNNLHRANNSILLSPGPDKPHNPLLSTLLEDKLPGGGGQPEVHDSPMLSRLLDDNISVATNVIPMTCKPNQPLIGGKRQRKRKSQSEMSGPSPKHRFGDSDSSDRMNPMGSSMDLDMGPGLMSQGLSSTPPIMSSMQSNLGSSTHLLHHHPHSSLNHAASLSRSQGNVIDLTEDSISAESSLKKLVDSVDKHFPHKDQDLMMFDSEASNRIPNMLQNSPSGSKNENASTSLEVYLKGSGEVGRAKDFDPSDVSTVHVSKLSTLLLAPSDSPTSTLNASSHKANSSFFSDGQLTSDNRIISLMQDIKPHQGCLLDGQCSNPEHPNDKQNVGIFEKFDRARQQQVGKVELSSAEIKSAPSEGKVSLKLRVGPLKQQNSVKPVVKSADKSNLKSNSITTFDFKSDEDEDETLLHYSDSVYSSSPTRLQISSGKHKRSSDASISLKTDKVKKKDRNSSSTTKRKREKEDSKREKKGKKXEHIIQESVYRTVENDSKTDFKLKIRVAKKPVTEKHDQLYDGKIQQSYEISKKSSSSPVEKIISNKQEVKEAISLLGENVKVKDVNASVHLHKSGSMTSVKPGTIATNTHKPSIKSLSSKPSQVSDNKTDTKLVSKATIRLKPLNMPNSGSTVNVNISQSGSKTSSTTLANSSKSDRRSSTSAAQPATDKRSAAHNTLLERRGSTSGLVERRNSLQSSSSATSSTAANTTSTSVNSSPVTTSANLSLSSILPNAPTGSKIASLPRIPKLPSSSNTLINRTSSLDPITDTSLTPQGTKANNSYNTGPAGRVNSSQGTAAGRPSANNNAAFNYNRQNFNVNRMQSANRQTSPGVNAGQISQQRAGNIRPHHPSGSSTQGSSAGQKQSSNSHKTGSSANSKSNNNPNASPKTGTTKINISGSSTKLGHSNLSTGQKSVTSGANAVSGQRQSSHGNIQRTPSNSSNVSRSPNTSSLTKSPSSGKSPNLSSAGRSPSLSTASKSPNITSGVNKSPNISSGVNRSPNISSGKSPNINASKSPNLTNHSSRPSPSSKSVHISSSHKQSANMSKSSNLSKGTSNVMKTPNSSINNVLGSSKSSHNKAVNKTIVPTSNNQISKTISLPSVCGTTTVTNAISSATGDNLSSPGALKSLLSHSSHSNSAPLLASPGLVTENLLVKSVREQVEHSNNFKDGNDINNICIPDKLSRSTSSTPTTPMSADSCKTKFPFPSSRGRKNSLSAIVDKLKHNAVGGGLDLLVAPSEGFKASLSTDSTKLQTDSSSEILRLEENKMLDASDTIEGAELINNLEGRVNHAIDSLTKTNDFLGEKSTSEYAKALLLDTEGSNKYFKTLEDKTKDFVKLTDTNLSMDLNIAREKNKSDFATSNSVPLKNINVENKKLNIKNKDKPSPLRILPTPSSPVVQSPVSGKLSPSVSPFHTPNSSPSNTPSVKSARVHKDTEEQIFKIPSVKPAPDQLEDSSDTIGHLANAKNGKLDVPDHTSGSARDNQDQKVSQEQSNTKHSSVKVLSSPLSDISSPENGLVIDDEESSGFTFRSGTEKSSLNNMLMKTQLYSSQVDKNVLNSVLLKPQLSPHISKDEVANSISQIHGDKSSSPMNNLEGVSIPGRLPSARSPALAKNPSGASTPKRSDSPCEIDDDLMDEALGFGS
Length2255
PositionMiddle
OrganismBiomphalaria glabrata (Bloodfluke planorb) (Freshwater snail)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Gastropoda> Heterobranchia> Euthyneura> Panpulmonata> Hygrophila> Lymnaeoidea> Planorbidae> Biomphalaria.
Aromaticity0.03
Grand average of hydropathy-0.613
Instability index54.05
Isoelectric point9.37
Molecular weight243079.78
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15584
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     309.32|      44|      45|    1550|    1593|       1
---------------------------------------------------------------------------
 1236- 1278 (40.86/10.85)	PLNM...PNSGSTVNV.N.ISQS.........G..SKTS.STTLA.NSSKSDRRSSTSAAQ
 1435- 1486 (41.25/11.03)	QSAN...RQTSPGVNAGQ.ISQQragnirphhP...SGS.STQGS.SAGQKQSSNSHKTGS
 1487- 1526 (36.68/ 8.90)	SANSksnNNPNASPKTGT..TKI.........N..ISGS.STKL....GHS.NLSTGQK..
 1551- 1593 (73.28/25.93)	.SNS...SNVSRSPNTSS.LTKS.........P..SSGK.SPNLS.SAGRSPSLSTASKSP
 1597- 1638 (45.38/12.95)	.......SGVNKSPNISSgVNRS.........PniSSGK.SPNI..NASKSPNLTNHSSRP
 1640- 1674 (33.73/ 7.53)	PS.............SKS.VHIS.........S..SHKQ.SANMSkSSNLSKGTSNVMKTP
 2003- 2036 (38.15/ 9.58)	...........PTP.SSP.VVQS.........P..VSGKlSPSVS.PF.HTPN.SSPSNTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     667.94|     174|     189|     623|     810|       2
---------------------------------------------------------------------------
  623-  797 (258.93/142.39)	..............LHRANNSiLLSPGPDKPHNPLLSTLLEDKLPGGGgqpevhdspmlsRLLDDNISVATNVIPMTCKPN.QPLIG..GKRQRKRKS.Q...SEMSGPSPKHRFGDSDSSDRMNPM.GSSMD.LDMGPGLMSQGL.......SSTPPIMSSMQSNLGSST..............HLLHHHPHSSLNHAASLSRSQGN..VIDLTEDSISA
  798-  898 (116.10/51.38)	ESSLKKLVDSVDkhF...............PHKD.QDLMMFD.........................SEASNRIPNMLQ.N.SP.SG..SKNENASTSlE...VYLKGSGEVGRAKDFDPSDVSTVH.VSKLStLLLAP...SDSP.......TSTLNASS............................................................
  899- 1059 (193.26/89.35)	...............HKANSS.FFSDGQLTSDNRIIS.LMQDIKPHQG............CLLDGQCS...N..PE..HPNdKQNVGifEKFDRARQQ.QvgkVELSSAEIK....SAPSEGKV......SLK.LRVGP..LKQQN.......SVKPVVKSADKSNLKSNSittfdfksdededeTLLHYSDSVYSSSPTRLQISSGK..HKRSSDASIS.
 1732- 1813 (69.61/23.94)	.........................................................................................................LSSPGALKSLLSHSSHSNSAP........LLASPGLVTENL....lvkSVREQVEHS..NNFKDG....................NDINNICIPDKLSRSTSStpTTPMSADSCKT
 1824- 1869 (30.04/ 6.69)	KNSLSAIVDKLK...HNA.............................................................................................................vGGGLD.LLVAP...SEGFkaslstdSTKLQTDSS...........................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.84|      17|      18|    2154|    2171|       3
---------------------------------------------------------------------------
 2154- 2171 (24.37/17.66)	LMKTQLySSQVDKN.VLNS
 2173- 2190 (24.47/12.15)	LLKPQL.SPHISKDeVANS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.63|      21|      98|    1203|    1228|       5
---------------------------------------------------------------------------
 1141- 1161 (27.52/ 9.45)	YEISKKSSSSPVEKIISNKQE
 1203- 1223 (36.11/30.14)	HKPSIKSLSSKPSQVSDNKTD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     458.64|     151|     189|     173|     330|       6
---------------------------------------------------------------------------
  173-  330 (234.66/162.40)	DEKLKS..KAFLALQALEK....D.LNQLSQ.FQSSISGVANYIHKCPLGIMLPRLAGKPMKLIYFVSPYDLLDKKSLTaHPLTVEAITENfLgQSVTVCLE.PVPDSASPNKLQTMPLMN....VSKTQEGKSLPSFSAVTKI..NSMMLPasfvLVLPQPLPISMQLLQKI
  357-  522 (223.98/135.14)	DGKIQDcrKLFVSLPDQRHiyflDgLNGVSQdLQGVMVSRIPFTHPTHVPQILNLLRQQLLFNIVLSSCIRPASKKEVL.NTIVFEVTTVS.L.QQLTIVFEhPAYDSMITVDIDLTDITNlkchITCTNPEHTLCTDDALSKVfqRCMSIP....IMLRWLVGIGRHHLDKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     172.43|      50|     106|    1279|    1328|       8
---------------------------------------------------------------------------
 1279- 1328 (81.70/45.77)	PAT..........................DKRSAAHNTLLERRGS......TS..............GLVERRNSLQSSS....SATSSTAANTTSTSVN
 1331- 1430 (49.87/24.42)	PVTtsanlslssilpnaptgskiaslpriPKLPSSSNTLINRTSSldpitdTSltpqgtkannsyntGPAGRVNSSQGTAagrpSANNNAAFNYNRQNFN
 2074- 2107 (40.86/18.38)	...............................LANAKNGKLDVPDH......TS..............G.SARDNQDQKVS....QEQSNT..........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.36|      17|      18|    2201|    2217|       9
---------------------------------------------------------------------------
 2201- 2217 (32.49/17.75)	SP..MNNLEGVSIPGRLPS
 2220- 2238 (26.87/13.17)	SPalAKNPSGASTPKRSDS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15584 with Med1 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKLQATMPTKGRPPPQPPHPTLPPPPSYTQIHYSVAPTHSHMSSNGQSQMVPMLLDSRTATEGMEDYRNFSDNNLHRANNSILLSPGPDKPHNPLLSTLLEDKLPGGGGQPEVHDSPMLSRLLDDN
2) ATNVIPMTCKPNQPLIGGKRQRKRKSQSEMSGPSPKHRFGDSDSSDRMNPMGSSMDLDMGPGLMSQGLSSTPPIMSSMQSNLGSSTHLLHHHPHSSLNHAASLSRSQGNVIDLTEDSIS
3) DVNASVHLHKSGSMTSVKPGTIATNTHKPSIKSLSSKPSQVSDNKTDTKLVSKATIRLKPLNMPNSGSTVNVNISQSGSKTSSTTLANSSKSDRRSSTSAAQPATDKRSAAHNTLLERRGSTSGLVERRNSLQSSSSATSSTAANTTSTSVNSSPVTTSANLSLSSILPNAPTGSKIASLPRIPKLPSSSNTLINRTSSLDPITDTSLTPQGTKANNSYNTGPAGRVNSSQGTAAGRPSANNNAAFNYNRQNFNVNRMQSANRQTSPGVNAGQISQQRAGNIRPHHPSGSSTQGSSAGQKQSSNSHKTGSSANSKSNNNPNASPKTGTTKINISGSSTKLGHSNLSTGQKSVTSGANAVSGQRQSSHGNIQRTPSNSSNVSRSPNTSSLTKSPSSGKSPNLSSAGRSPSLSTASKSPNITSGVNKSPNISSGVNRSPNISSGKSPNINASKSPNLTNHSSRPSPSSKSVHISSSHKQSANMSKSSNLSKGTSNVMKTPNSSINNVLGSSKSSHNKAVNKTIVPTSNNQ
4) EKHDQLYDGKIQQSYEISKKSSSSPVEKIIS
5) FPHKDQDLMMFDSEASNRIPNMLQNSPSGSKNENASTSLEVYL
6) INVENKKLNIKNKDKPSPLRILPTPSSPVVQSPVSGKLSPSVSPFHTPNSSPSNTPSVKSARVHKDTEEQIFKIPSVKPAPDQLEDSSDTIGHLANAKNGKLDVPDHTSGSARDNQDQKVSQEQSNTKHSSVKVLSSPL
7) NSVLLKPQLSPHISKDEVANSISQIHGDKSSSPMNNLEGVSIPGRLPSARSPALAKNPSGASTPKRSDSPCEIDDDLMD
8) SPTRLQISSGKHKRSSDASISLKTDKVKKKDRNSSSTTKRKREKEDSKREKKGKKXEHIIQESV
549
678
1177
1127
812
1981
2170
1039
674
796
1704
1157
854
2119
2248
1102










Molecular Recognition Features






MoRF SequenceStartStop




NANANA