<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15560

Description Uncharacterized protein
SequenceMDYEFKLKTTQERARVEDEFEYEGCKVGRGTYGHVYKATRKDGDRKQNYALKLIEGTGISMSACREIALLRELKHPNVISLLKVFLSHQDRKVWLLFDFSEHDLWHIIKYHRSAKANKKPINTPKNMVKSLLHQILAGIHYLHSNWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLAARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHQQLTRDFKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPTKRISSEQAMKDPYFSEEPTPCADVFEGMPIPYPKREFISDDDNEDKSDTNKQQQTAGGAGGGGSDHNQPPAKRARMAPTSSNNSMVSGDYQHVHNMAGGSQQQGMTYNSNSQSQQQNTSASSFGQRMI
Length449
PositionKinase
OrganismBiomphalaria glabrata (Bloodfluke planorb) (Freshwater snail)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Gastropoda> Heterobranchia> Euthyneura> Panpulmonata> Hygrophila> Lymnaeoidea> Planorbidae> Biomphalaria.
Aromaticity0.09
Grand average of hydropathy-0.695
Instability index45.70
Isoelectric point8.76
Molecular weight51502.97
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15560
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.44|      15|      36|     151|     165|       1
---------------------------------------------------------------------------
  151-  165 (26.77/21.02)	DLKPANILVMGEGPE
  189-  203 (28.67/23.05)	DLDPVVVTFWYRAPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.43|      37|      40|     352|     388|       2
---------------------------------------------------------------------------
  352-  388 (66.54/47.55)	PYPKREFI...SDDDNEDKSDTNKQQQTAGGAGGGGSDHN
  390-  429 (62.89/44.53)	PPAKRARMaptSSNNSMVSGDYQHVHNMAGGSQQQGMTYN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.52|      25|      36|     279|     305|       3
---------------------------------------------------------------------------
  279-  305 (41.23/37.36)	LTRD.FKRSSyvNCNLMK...YMEKHKVKAD
  316-  344 (36.29/25.02)	LTMDpTKRIS..SEQAMKdpyFSEEPTPCAD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15560 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) YPKREFISDDDNEDKSDTNKQQQTAGGAGGGGSDHNQPPAKRARMAPTSSNNSMVSGDYQHVHNMAGGSQQQGMTYNSNSQSQQQNTSASSFGQRMI
353
449










Molecular Recognition Features






MoRF SequenceStartStop




1) IPYPKREF
2) PAKRARMA
351
391
358
398