<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15559

Description Uncharacterized protein
SequenceMDYEFKLKTTQERARVEDEFEYEGCKVGRGTYGHVYKATRKDGDRKQNYALKLIEGTGISMSACREIALLRELKHPNVISLLKVFLSHQDRKVWLLFDFSEHDLWHIIKYHRSAKANKKPINTPKNMVKSLLHQILAGIHYLHSNWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLAARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHQQLTRDFKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPTKRISSEQAMKDPYFSEEPTPCADVFEGMPIPYPKREFISDDDNEDKSDTNKQQQTAGGAGGGGSDHNQPPAKRARMAPTSSNNSMVSGDYQVYLTQPNNQSSHSSSYQHGISMTYSNSYHSNDYSVYQNSSYDPWHVHNMAGGSQQQGMTYNSNSQSQQQNTSASSFGQRMI
Length493
PositionKinase
OrganismBiomphalaria glabrata (Bloodfluke planorb) (Freshwater snail)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Gastropoda> Heterobranchia> Euthyneura> Panpulmonata> Hygrophila> Lymnaeoidea> Planorbidae> Biomphalaria.
Aromaticity0.10
Grand average of hydropathy-0.743
Instability index45.30
Isoelectric point8.48
Molecular weight56610.20
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats
>MDP15559
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.04|      28|      35|     404|     436|       1
---------------------------------------------------------------------------
  404-  436 (49.94/38.75)	NSMVSGDYQVYltqpnNQSSHSSSYQH...GIS....MTY
  438-  472 (49.10/27.34)	NSYHSNDYSVY.....QNSSYDPWHVHnmaGGSqqqgMTY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.44|      15|      36|     151|     165|       2
---------------------------------------------------------------------------
  151-  165 (26.77/21.08)	DLKPANILVMGEGPE
  189-  203 (28.67/23.13)	DLDPVVVTFWYRAPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.61|      30|      36|     263|     298|       3
---------------------------------------------------------------------------
  257-  286 (58.07/30.52)	NVMGF.PQDKDWEDIRKMPEHQQ.LTRD.FKRS
  292-  324 (35.53/31.43)	NLMKYmEKHKVKADSKAFHLLQKlLTMDpTKRI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.95|      11|      16|     328|     338|       4
---------------------------------------------------------------------------
  328-  338 (20.76/13.21)	QAMKDPYFSEE
  347-  357 (22.18/14.63)	EGMPIPYPKRE
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15559 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SVYQNSSYDPWHVHNMAGGSQQQGMTYNSNSQSQQQNTSASSFGQRM
2) YPKREFISDDDNEDKSDTNKQQQTAGGAGGGGSDHNQPPAKRARMAPTSSNNSMVSGDYQVYLTQPNNQSSHSSSYQHGISMTY
446
353
492
436










Molecular Recognition Features






MoRF SequenceStartStop




NANANA