<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15540
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MSLQGKVALITGGTKNLGAEIARQLATAGASLALHYNTDSSRTAGEALVRELGAKVKVEMFQADLRTEKAVDALFEDVVRGFGRVDVVVNTVGKVLKRGILEVSEGEYDDMFAINSKSAFFILKAGARHVSDGGKIITIVTALLAAFTGLYTSYAGSKAPVEHFTRGVAKELQPRGISVNCVAPGPMDTPFFYPQESEQAVAFHKSQGMGGRLTEVGDIAPLKSDAISGTTFTQQLKDIIQDLYQVMVQVTTYDAAGRPSREVLSNEM |
Length | 268 |
Position | Middle |
Organism | Ophiocordyceps camponoti-rufipedis |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Hypocreales> Ophiocordycipitaceae> Ophiocordyceps.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.009 |
Instability index | 29.60 |
Isoelectric point | 6.12 |
Molecular weight | 28680.40 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
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GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | oxidoreductase activity GO:0016491 IEA:InterPro
transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP15540
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 60.09| 21| 24| 83| 106| 1
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86- 106 (34.21/24.84) D..VVVNTVGK..VLKRGILEVSEG
109- 133 (25.88/10.05) DdmFAINSKSAffILKAGARHVSDG
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 51.22| 21| 24| 25| 48| 2
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25- 48 (28.40/28.42) LataGASLALH.YNTD.SSRTAGEAL
52- 74 (22.82/13.97) L...GAKVKVEmFQADlRTEKAVDAL
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