<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15478

Description CMGC/CDK/CDK8 protein kinase
SequenceMSLSNPPHSTGGGSLSDAASGRSTYASRSSAAALNNNGNSTLGLKRSVQAAFDDTLEPKKSPGGGYTSKVHIREKYHIVGFISSGTYGRVYKAIGRNGQKREFAIKKFKPDKEGEIVQYTGLSQSAIREIALCSELSHANVIHLEEIILEDKCIFMVFEYTEHDLLQIIHHHTQPQRHAIPAPMVKSILFQLLNGLLYLHTNWVLHRDLKPANILVTSTGAVRIGDLGLARLFYKPLNSLFSGDKVVVTIWYRAPELLLGSRHYTPAIDLWAVGCIFAELLSLRPIFKGEEAKMDSKKTAPFQRNQMLKIIEILGVPKKESWPGLVSMPEYAQLQSLALARAGSHLNKPSNLEAWYHTCVKSAGYPSSPSGSPGKEGFDLLSRLLEYDPEKRLTAEEALEHPYFSIGTPVTANCFEGFEGKYPNRRVSQDDNDIRTSSLPGTKKSGLPDDTLTARAAKRHKEG
Length463
PositionKinase
OrganismEmmonsia crescens
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Onygenales> Ajellomycetaceae> Emmonsia.
Aromaticity0.08
Grand average of hydropathy-0.343
Instability index46.68
Isoelectric point9.08
Molecular weight51153.76
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15478
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     178.56|      55|     395|       3|      59|       1
---------------------------------------------------------------------------
    3-   59 (88.71/52.86)	LSNPPHSTGGGSLSDAASG.RSTYASRSSAAALNNNGNSTL.GLKRSvqAAFDDTLEPK
  399-  455 (89.85/48.61)	LEHPYFSIGTPVTANCFEGfEGKYPNRRVSQDDNDIRTSSLpGTKKS..GLPDDTLTAR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.60|      39|     109|     204|     253|       3
---------------------------------------------------------------------------
  204-  253 (55.83/56.64)	VLHRDLKPAniLVTSTGAVRIGDLGLARL...FYKPLNslfsgdkvvVTIWYR
  316-  357 (65.77/40.72)	VPKKESWPG..LVSMPEYAQLQSLALARAgshLNKPSN.........LEAWYH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     127.14|      30|      90|     164|     193|       4
---------------------------------------------------------------------------
  164-  193 (54.08/37.46)	DLLQIIHHHTQPQRHAIPAPMVKSILFQLL
  256-  281 (43.99/29.14)	ELLLGSRHYT.P...AIDLWAVGCIFAELL
  282-  303 (29.07/16.82)	SLRPIFKGEEAKMDSKKTAP......FQ..
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15478 with CDK8 domain of Kingdom Fungi
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