<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15423

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMENHKAKLIHILEDALGVEAMETAFCGMIVHNEEDEDRDIKEIFQRDFKLFWAGVLVDAREQLLLDFVSFIYNEHNPRRIDIAFGLLGSLVESSLVPARLMCEAILKTPHLSFQKELMWCKTFQLLLKIVGGVDYKSCRDILSLVFHLFRNIPTTADPAFTDRIQACVKVVRYILDRNICLLPAYFVINEIYKIFPEGKVKPHWAIAKLLSDFAETFRPLARTVSVIGRPSLLPVIGHPGSSISVWKLDPNTLSFPLKGLLPYDKDLLEPQTKLLQYVIAQPYSRDVICTMLGLNKQQKQRCQALEELLVDLIVVAMERSEANEANMSETGCQLLWHHLSSHLIFFVLFQFASFPHMVLSLYTKLSGRNLKRGRDHLMWVLLQFISGSIQKNPLSDFHPVMKLFDLLYPEKQPLPIPDITSADSVHSLAMACIWIHLSKKAQSEDVTWRPPVPHILKDQIEFIQNRSGGASSFSLNNYKIPLLCNAYSTNPEYFSVPMAMLVEMCYGNNKGSTQLPGPSNTLAAAPTVPCPMSLLDSLTVHAKMSFIHSIVNRIIKLGNSQFTLALAPALVETYSRLLVYMEIESLGIKSFISSLLPNVFKSHAWGILHTLLEMFSYRLHHIQPHYRVTLLSHLHSLAAVPHTNQNQLHLCVESTALRLITGLGSSEVQPQLSRFNSEPKQLLSAESEELNRALVLTIARAMHITSAESSTNWYEGILRSLITNTPHSWASHTLACFPQPLRQFYTKNPCPHETKQELRQRVDDEFRRWRAMSSEKEILNHFADPSSTNVFICILWKMLLDSNRLNSVCHKVLERLGARALSAHVRVFADYLVYEFSTSAGGKHINKCIIHLNDLIWKYNVVTLDRLVLCLALRSHEGNEAQVCFFIIQLLLLKPQDFRNRVNSFIRDNSPHHWQQNEWHQKHMNYHTSYPERFYFEGLLESAGATVPTVQYLPIYFENVCLRFLPVFDIVIQRFLELAPVHKSLESLLDHLGCLYKFHDRPVTYLYNTLHYYEHCLRDKAALKKKLVGAITSAQKDVHPEGWCLSRGYLEFLSKPEDSWTPDLTYYCSLIGRLVDTIAGKTPPPFPACDWRFNEFSNPVAHALHVTWVELMALPVKGPDVGNALFDVIFKGSYVTHDSDIRTNIMEWINAVGLVLSALPEPYWSVVYDKICMALRRELSAKEVSTTPIVLENLGRAAPFPYSFLEFSTNVAMHSETTADYVLAVVHAVWHHASIGQLSQLPQFLRDRVSPLVTNEAQFLYVCHLVGPFLQRLIQERPRCVQEIVVVLYHLLEKINREVQHIHHVDTICDFLYHIKYMFIGDVIKDEVLKIIPQLRQSLQIRLRFMTQNVKRDDTTTFA
Length1359
PositionTail
OrganismStylophora pistillata (Smooth cauliflower coral)
KingdomMetazoa
LineageEukaryota> Metazoa> Cnidaria> Anthozoa> Hexacorallia> Scleractinia> Astrocoeniina> Pocilloporidae> Stylophora.
Aromaticity0.10
Grand average of hydropathy-0.001
Instability index43.12
Isoelectric point7.24
Molecular weight155664.80
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15423
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.96|      17|      32|     344|     360|       1
---------------------------------------------------------------------------
  344-  360 (31.91/19.36)	IFFVLFQF..ASFPHMVLS
  377-  395 (27.05/15.29)	LMWVLLQFisGSIQKNPLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     776.13|     262|     376|     541|     820|       2
---------------------------------------------------------------------------
  541-  638 (93.76/47.15)	.........................................................................................................................................................................................................................................................HAK.MS..FIHSIVNRIIKLGNSQFTLALAPALVETYSRLLVYME........IESLGIKSFISSLLPNVFKSHAW......GILHTLLEMFS..YRLHHIQP.HYRVTLLSHLHSLA
  642-  820 (209.51/171.32)	HTNQNQLHLCVestALRLITGlGSSEV..........QPQ..LSRFNSePKQLL....SAESEELNRALVLTIARAMHITSAESStnWYEGILR..SLITNTPHSWASHTLACFPQPLRQFYT.KNPCPHETKQ.................................ELRQRVddefRRWraMSSEKEILNHFADPSSTNVF..ICILWKMLLDSNRLnSVCHKVLERLGaRA......................................................................................................................................
  865- 1014 (141.16/81.38)	....DRLVLCL...ALRSHEG.NEAQVcffiiqllllKPQdfRNRVNS..........................................................................................................................................................................................firdnsphhwqqnewHQKhMN..YHTSYPERFYFEG....LLESAGATVPTVQYLPIYFEnvclrflpVFDIVIQRFLE.LAP.VHKS...........LESLLDHLGclYKFHD.RPvTY...LYNTLHYYE
 1015- 1313 (331.69/200.97)	HCLRDKAAL........................................KKKLVgaitSAQKDVHPEGWCLSRGYLEFLSKPEDS..WTPDLTYycSLIGRLVDTIAGKTPPPFPACDWRFNEfSNPVAHALHVtwvelmalpvkgpdvgnalfdvifkgsyvthdsDIRTNI....MEW..INAVGLVLSALPEPYWSVVYdkICMALRRELSAKEV.STTPIVLENLG.RAapfpysflefstnvamHSE.TTadYVLAVVHAVWH.HASIGQLSQLPQFLRDRVSPLVTNE........AQFLYVCHLVGPFLQRLIQERPRcvqeivVVLYHLLEKIN..REVQHI...HHVDTICDFLY...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.16|      22|      33|     479|     501|       3
---------------------------------------------------------------------------
  479-  501 (35.91/26.09)	KIPLLCNAYSTNPEyFSVPMAML
  514-  535 (40.25/24.00)	QLPGPSNTLAAAPT.VPCPMSLL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15423 with Med23 domain of Kingdom Metazoa
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