<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15422

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMVVAGDLYENDVIFVVEGTANLLLDFENLKKSYIEPAIHYFNGEVPVDSEYSFGDEYGPNQYGLVVYGTISHTAEPAVHYVKETRSAKQMLQYLDDVRFEGGGGEECSLLAEALSIALQIFDERTLQRGQHKGIVRKSCIVVSNSPPFGLPSRECADDYLDKNVEQLAEEMGQKKGVHLSIIAPRKILALQRVFERSLTVDSKSVLSKDYSRDPNHLVCIQGLDLPVTCKNESQAETVKSNPFMVDPNMKLVPTPQMINNGKESPEKPIKKPKIGPRQPSEVKIQQPTPDVNLSIPSVNNATSGAQSSSAAHQAKQILEIAKQQQQRQPNPTPNSGQPANKMPDAIKVTPGNWPPNPTPSSRPAPTPVPTTQENPVAQRALVWTGNLEWQDTIRDPAGPQQKVTRSLACHASVVPGDTIKANNWPPKLIMQLIPQNLLSTLGPLLQNSKTVAFHFAPNDQESLKALYRVMASHGIKFAGCVHFPPVPQCDVKVLLLIFSPKKRAFVGLIPVEQANFVDGIRNVVQKYKADQLSRIAMQRQRMLLQIKQHQQQQQQQQQQQQQQQQPQPQQQTPQQASFAAAGIPQGQFPPQQSQVSQQPLLNSVGHALITSATPGLGQNPEGLATSTQTSVAANMGLSFSGVGTGTHTMPVLQQIEQQDNPALLHTLKLFQQQQQQQQQQQQQQQQQQQLQQSQQLTPQQQMLVRRQQHQLQQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTFPAQDNQVQQMQASQGIQSQLRHLLQSQANQASAQQQGLATSQPGMTQQQWQLLQLQQQRSQAAVQMPLGQVQMTQASMSQGQPSQAQLQVHQQQQQLAQSQSSYLPDNMSFIDMMRQ
Length869
PositionUnknown
OrganismStylophora pistillata (Smooth cauliflower coral)
KingdomMetazoa
LineageEukaryota> Metazoa> Cnidaria> Anthozoa> Hexacorallia> Scleractinia> Astrocoeniina> Pocilloporidae> Stylophora.
Aromaticity0.05
Grand average of hydropathy-0.730
Instability index68.72
Isoelectric point8.57
Molecular weight97070.12
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15422
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     388.81|      57|      60|     671|     727|       1
---------------------------------------------------------------------------
  536-  594 (77.65/16.64)	AMQRQRML...............................................L.QIKQHQQQ........QQQQQQQ.....QQQQQQPQPQQQTPQQasfaaagipQGQFppQQSQ.
  595-  695 (68.67/13.72)	.VSQQPLLnsvghalitsatpglgqnpeglatstqtsvaanmglsfsgVGTGTHTMPVLQQIEQQ........DNPALLHtlklfQQQQQQQQQQQQQQQQ.........QQQL..QQSQQ
  696-  750 (107.68/26.40)	LTPQQQML........................................VRRQQHQLQQLQQQQQQ........QQQQQQQ....qQQQQQQQQQQQQQQQQ.........QQ....QQ.QQ
  751-  795 (65.93/12.83)	TFPA...............................................QDNQVQQMQASQGI........QSQLRHL.....L.....QSQANQASAQ.........QQGL..ATSQP
  797-  853 (68.89/13.79)	MTQ................................................QQWQLLQLQQQRSQaavqmplgQVQMTQA....sMSQGQPSQAQLQVHQQ.........QQQL..AQSQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     183.72|      28|      71|     328|     355|       2
---------------------------------------------------------------------------
  247-  277 (26.93/10.12)	.PNmklvPTPqmiNNGKESPEKP..I....K.KPK......I..GP...R
  286-  308 (33.93/14.85)	QPT....PDV...NLSIPS..VNNA.......TSG......A..QS...S
  328-  355 (58.38/31.36)	QPN....PTP...NSGQPANKMPDAI....KVTPG......N..WP...P
  362-  394 (36.90/16.85)	RPA....PTP...VPTTQENPVAQRA....LVWTG......NleWQdtiR
  395-  426 (27.58/10.56)	DP............AG.PQQKVTRSLachaSVVPGdtikanN..WP...P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.69|      21|     152|      41|      61|       4
---------------------------------------------------------------------------
   41-   61 (39.91/31.00)	FNGEVPVDSEYSFGDEYG..PNQ
  194-  216 (31.78/23.11)	FERSLTVDSKSVLSKDYSrdPNH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15422 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HALITSATPGLGQNPEGLATSTQTSVAANMGLSFSGVGTGTHTMPVLQQIEQQDN
2) IKQHQQQQQQQQQQQQQQQQPQPQQQTPQQASFAAAGIPQGQFPPQQSQVSQ
3) KNESQAETVKSNPFMVDPNMKLVPTPQMINNGKESPEKPIKKPKIGPRQPSEVKIQQPTPDVNLSIPSVNNATSGAQSSSAAHQAKQILEIAKQQQQRQPNPTPNSGQPANKMPDAIKVTPGNWPPNPTPSSRPAPTPVPTTQENPVAQRAL
606
546
230
660
597
381










Molecular Recognition Features






MoRF SequenceStartStop




NANANA