<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15421

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMVVNTEILLQAWRERWSPLRWLVEVKKLAGKDNEELQDLAECLVQQATFGSTPSTLILSYLNHGISTKVISCSSALTAVHQFQNIIKHKCLSALLDLLLSFIPTISGPDSDEECLRLAVSFIKILYWLLIVSTRLLKLCIESLRLSGGINLPFHSANIGKCHRAFGQLIGSSSYRAMVIVGKMEDQVTALELDRQLQAHLKDLLMTQPDGVVPEVQLYIKELMVNFSRFQSLNSSSGSGDISPGHVPNMPIQIITQFQVVVSPFYTPHQVADVMESTMHTQNVARHQLYLEFLRSALVGLLGAPEKSMEMILWTGFLFLKVPMVIRLLESRSQPPIQLQPSPVEHSAAHTAFQQLLQFAPLLDDADKKCRCNCYKELILQYCKDLNQQVVDRIGQLISQRLLSDEVQHLLSIQASYNHPAQQVQDEESKIMEIIMALESDLSSRDEKFLNPLLNVEKFRWMTVAAASVGKLPNLINGLVKVTEQTLRPATEKEDVKKGSIRGELFNTSFLLLCHIGQVYGSKVISEVAKNRSPTPFVVQWILRHIPDIDKWRSFIPDTQHTPNHAAVNELLNQFFSNSAFPASQANWDEHCTNVSSALHHVLNASQWESKAVPSDHLQKLCELLKYEAPALAVCACSWSCGHIYTLTAEERKHPMRLVGLLVKPVNPRGFSQGFVDRCAMLCEVMKTMSSSIEGKDNTWDIDNPICKGEPVSKTLASLFTSVVKARQLSSKTLKRFRHMLIMGGNEWFIYCIIQEVLKCSRHRDILMAADLASCLLTFDSENLVPCFLEKVLPLVMNHVEAETMLEDPKGWAIARLMAHAVCLGMTIEHTRSKGDLTDGEITRPAKIQRLDSFPSLYNSTSSSRVQQTLVHLCEDFIATIKTTEVGPVPALLVSFLQQAVASIGTIVGPLSACLPEDLVKEILELSPSLQNTPDVLLGLCNMKTTEGRQLCAKALCSSI
Length959
PositionTail
OrganismStylophora pistillata (Smooth cauliflower coral)
KingdomMetazoa
LineageEukaryota> Metazoa> Cnidaria> Anthozoa> Hexacorallia> Scleractinia> Astrocoeniina> Pocilloporidae> Stylophora.
Aromaticity0.06
Grand average of hydropathy0.029
Instability index47.75
Isoelectric point6.45
Molecular weight107101.20
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15421
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     259.17|      83|     438|      19|     109|       1
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   20-  109 (130.95/106.97)	RWLVEVKKLAGKdneeLQDLAECLVQQATFGSTPST...................LILSYLNHGISTKVISCSSALTAVHQF..QNIIKHkclSALLDLLLSFIP.TISGPD
  459-  563 (128.22/82.74)	RWMTVAAASVGK....LPNLINGLVKVTEQTLRPATekedvkkgsirgelfntsfLLLCHIGQVYGSKVISEVAKNRSPTPFvvQWILRH...IPDIDKWRSFIPdTQHTPN
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     176.87|      57|     440|     263|     331|       2
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  263-  331 (80.01/85.95)	PFYTPHQVADVMEStMHTQNVARHQL...YLEFLRSALVglLGAPEksmemilWtgFLFLKVPMVIRLLESR
  704-  763 (96.86/66.23)	PICKGEPVSKTLAS.LFTSVVKARQLsskTLKRFRHMLI..MGGNE.......W..FIYCIIQEVLKCSRHR
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.21|      26|     730|     179|     205|       5
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  179-  205 (41.40/32.76)	IVGKM.....EDQVTA.LELDRQLQAHlKDLLM
  906-  937 (34.81/22.02)	IVGPLsaclpEDLVKEiLELSPSLQNT.PDVLL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.25|      33|     479|     111|     144|       6
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  111-  144 (52.49/34.29)	DEECLRLAVSFIKILY...W..LLIVSTRLLKLCiESLR
  588-  625 (50.76/28.85)	DEHCTNVSSALHHVLNasqWesKAVPSDHLQKLC.ELLK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15421 with Med24 domain of Kingdom Metazoa
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