<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15400

Description Cyclin-dependent kinase 8 (Fragment)
SequenceMALAVVSQDYWSEMERCTIRERCKLMFNNELLSDVKFVVRDTEAGSESMKTIPAHKFVLAISSPVFYAMFYGELAETKDSINISDCEYRGVLELFRFIYSDEVHLNADNVMQVLYLAKKYMFLSLVDKCMELLGENVDASNVFHVLQVAQKYEAKELVEKCWKVIDEHGDEAVKAAAFATVEKSLLEELVERDSLKVTEVELFKAVDCWAGHECEKKNLALEGSVKRRVLGERIVGNIRFPVMEEKEFVEVVLDCEILTPKEAYNMMKYFNGVLPNLVGFLESKRSGPQRGWLDSFKNYFKPGVFVNYIPNKITCTLSVNKTIELQAVRLFGSEDKEYDVELILCDNYGLNVATVRGTFSSIPMESDMGNYHGFDVIFEPAPTVRANKSYTFTADFKGSASCYGKETGNQRCSTATQNRGSSRIIKTWRQFMLAHERSICFSVMDFEFKLKTNEQRERVEDKFDFEGCKVGRGTYGHVYKAKQKDCPNGKYFALKQIEGTGISMSACREIALLRELKHPNVIALQRVFLSHADRKVWLLFDFAEHDLWHIIKYHRASKAQKKAVPVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGPEKGRVKI
Length614
PositionKinase
OrganismStylophora pistillata (Smooth cauliflower coral)
KingdomMetazoa
LineageEukaryota> Metazoa> Cnidaria> Anthozoa> Hexacorallia> Scleractinia> Astrocoeniina> Pocilloporidae> Stylophora.
Aromaticity0.11
Grand average of hydropathy-0.238
Instability index33.63
Isoelectric point6.97
Molecular weight70299.29
Publications









Function






Annotated function


GO - Cellular Component
cytoplasm	GO:0005737	IEA:UniProtKB-KW

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15400
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.18|      30|      30|     106|     135|       2
---------------------------------------------------------------------------
  106-  135 (53.56/42.33)	NADNVMQVLYLAKKYMFLSLVDKCMELLGE
  138-  167 (53.62/42.39)	DASNVFHVLQVAQKYEAKELVEKCWKVIDE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.61|      41|      44|     168|     208|       5
---------------------------------------------------------------------------
  168-  208 (64.90/48.35)	HGDEAVKAAAFATVEKSLL.EELVERDSLKVTEVELFKAV..DC
  212-  255 (60.71/44.74)	HECEKKNLALEGSVKRRVLgERIVGNIRFPVMEEKEFVEVvlDC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15400 with CDK8 domain of Kingdom Metazoa
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