<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15337

Description Mediator of RNA polymerase II transcription subunit
SequenceMETKVTSKTSSLKALLLRAWRERWSDLQWGINIKTILPRGVSGDVYNLADCILQQALVGLGPNQLVLSYLKHSLSSQLVSYAAVLQRISKYDAFHKPHCILSLLEFLESIQIGITCRGKPEEDLLAAAVLSIVNWLLQCYLHTLTKMPQNNPLTPQPTELMDKPASILKQMLSSDFLCAMMYLAKYDDKDLYIEVVKKCQEIEALLKTSSLKSSIQIEDSLKKLCNLEDDCLTLSPEMSQMESITHCLQPLFAVQVLLNPSTETSVFVNQMLMVQRLKNYTNTRLYCEIIRACLMCLHNVTSTINESQWGAFTFLKVPLILKELHVAHSNADDKLEYSQDILDAFELLLQFTPLLDIVDTACSCNSVECLLNALQKVNLVTEKQTKHLSSRREGVTANLQKLEISIATSSIPKVIVRAEPTLSGILKTLNADYTKIHEALLSMLYQVLTGNSFELILAVATVEGKLKTFVTKLIKFNECSKQINEPVPPKTAAKRAMLFDISFLMLCSIVQTYGSDAVLEEGEGDSFFEQWVREYMPERNQPKSPQKMLQNIDPARVDALLAQINSPDPDLKSSNIKWHIACQSAMGAVKELLCAWESDVLGASDVKRALDGLRATACCLPVCAAAWLCAHMSITHQDALLKPLNMVQHFLTPLPGDEMQDNLKELSSLMSQIIRKMQYDVHPPTQSKTKVLSMSHSIISRQPILEQLETVWGNINQRGWINIQATQSLESLLNTGGSLWFVTNIVKEVLKYRYQEELDQAVDLAFATFHLDIENCTLDLINHIIPQYLYNSLQSEELVEPQSSVLAKLCVYCIFSTLEYNNSTPCRGNNRKRVRRDLDAEELDALGVPANKILRLNEAGDTNPIFGSQSPQAQGSTNGQKSVVLRDPLLSALNGLFTIFTFLAGRDGEVSQQTHFILQFLRLMVQCGKDRTRIVLQGMPQTLVPCLLKALPELFTTDILLRFYDIQTAVGRKATARDLCMLRNINLKPSK
Length991
PositionTail
OrganismApis cerana cerana (Oriental honeybee)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Apoidea> Apidae> Apis.
Aromaticity0.06
Grand average of hydropathy-0.024
Instability index50.17
Isoelectric point6.22
Molecular weight111252.00
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15337
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     181.48|      60|     198|     195|     263|       1
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  196-  260 (89.49/54.99)	VKK..CQEIEALLKTSSLKSSIqieDSLKKL.CNLeDDCLT..LSPEMSqMESITHCLQPLFAVQVLLNP
  589-  653 (91.98/39.48)	VKEllCAWESDVLGASDVKRAL...DGLRATaCCL.PVCAAawLCAHMS.ITHQDALLKPLNMVQHFLTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     248.91|      82|     283|     386|     475|       2
---------------------------------------------------------------------------
  386-  475 (112.32/112.89)	KHLSSRREGVTANLQkLEISIATSSIPKVIVRAEPTLS..GILKTLNADYTKIHEallSMLYQVLTGNSFELILAVAtveGKLkTFVTKLIK
  664-  747 (136.59/106.60)	KELSSLMSQIIRKMQ.YDVHPPTQSKTKVLSMSHSIISrqPILEQLETVWGNINQ...RGWINIQATQSLESLLNTG...GSL.WFVTNIVK
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     314.53|     109|     711|      63|     195|       3
---------------------------------------------------------------------------
   63-  195 (158.83/174.51)	NQLVLSYLKHSL.SSQLV.SYAAVLQRISKYdafhkphCILSLLEFLESiqigITCRGKPEE....DLLAAAV..LSI.VNWLLqcylHtLTKMPQNNPL....TPQPTELMDKPASIlkqMLSSDFLCAM.......MYLAKYDDkdlyiEV
  782-  910 (155.70/110.20)	NHIIPQYLYNSLqSEELVePQSSVLAKLCVY.......CIFSTLEYNNS....TPCRGNNRKrvrrDLDAEELdaLGVpANKIL....R.LNEAGDTNPIfgsqSPQAQGSTNGQKSV...VLRDPLLSALnglftifTFLAGRDG.....EV
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.08|      33|     575|     338|     374|       5
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  338-  374 (53.52/37.72)	SQDildaFELLLQFTPLL........DIVDTACSCNSVECLLNAL
  911-  951 (52.56/28.72)	SQQ....THFILQFLRLMvqcgkdrtRIVLQGMPQTLVPCLLKAL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15337 with Med24 domain of Kingdom Metazoa
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