<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15325

Description Uncharacterized protein
SequenceMVPKSMVKSILYQILDGIHYLHSNWILHRDLKPANILVMGDGPPSVRGRVKIADMGFARIFSNPLKPLAELDPVVVTFWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTSEPVFFCKEEDIKAQSPYHYDQLKRIFSVMGYPSEADWSDIKKMPDYQKLHMDLKNQNATFGSCSMQRYMEKYKIESETQQFKLLLKLLTMDPIKRISCKDAMEDNYFKTDPKPTEDVFYKFDIPYPKRDYLPENDVKKSHAMPTEEQNTNPPINQADSEPANKRMRVMNAHNNGSSLKIGGTNSGTMYGASGAQTQSIQVQQAASSNRPITSGQEMHLQGNNQMQSSGASDMQQPIGAMSNQQPPAHHMHQQNMQGMMQQPGHHQQFHPGQTQPQQMFQNQPMPAQMMQPQQTHPQPGHYPMGMMQNQQQQQQQQQQQMMARQGAQGGHPHGQMGQAHPQMMGHGNQQAPPPYGMQNNDNMMMQGGQYMGQVQMGPGNNMNVQHGQWQQHRYQ
Length504
PositionKinase
OrganismDiploscapter pachys
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Diploscapter.
Aromaticity0.08
Grand average of hydropathy-0.852
Instability index51.13
Isoelectric point8.17
Molecular weight57352.58
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15325
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     278.85|      44|      46|     343|     387|       1
---------------------------------------------------------------------------
  305-  341 (32.95/ 6.12)	QTQSIQ.VQQ...A....ASSNRPitSGQEMH...LQGnnQMQSSGA.S......
  343-  381 (70.24/24.56)	.......MQQPIGA....MSNQQP..PAHHMHQQNMQG..MMQQPGH.HQQFHpG
  382-  405 (40.24/ 9.11)	QTQPQQmFQ...........NQPM..PA.....Q.......MMQP....QQTH..
  406-  446 (60.64/17.67)	...PQP.GHYPMGM....MQNQQQ..QQQQQQQQMMAR..QGAQGGHpHGQM..G
  447-  477 (38.04/ 8.21)	QAHPQ.........mmghGNQQAP..PPYGM..QNNDN..MMMQGG.........
  478-  504 (36.73/ 7.67)	.........QYMGQ....V..QMG..PGNNMNVQ..HG..QWQQ..H.RYQ....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.54|      25|      27|     219|     245|       2
---------------------------------------------------------------------------
  219-  245 (42.92/32.16)	KTDPKPTEDvfYKFDIPYPKRDYLPEN
  249-  273 (45.62/27.60)	KSHAMPTEE..QNTNPPINQADSEPAN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.38|      21|      30|     121|     150|       4
---------------------------------------------------------------------------
  123-  144 (35.74/35.83)	KAQSPY...HYDqLKRIFSVMGYPS
  152-  175 (35.64/11.01)	KKMPDYqklHMD.LKNQNATFGSCS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15325 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) YLPENDVKKSHAMPTEEQNTNPPINQADSEPANKRMRVMNAHNNGSSLKIGGTNSGTMYGASGAQTQSIQVQQAASSNRPITSGQEMHLQGNNQMQSSGASDMQQPIGAMSNQQPPAHHMHQQNMQGMMQQPGHHQQFHPGQTQPQQMFQNQPMPAQMMQPQQTHPQPGHYPMGMMQNQQQQQQQQQQQMMARQGAQGGHPHGQMGQAHPQMMGHGNQQAPPPYGMQNNDNMMMQGGQYMGQVQMGPGNNMNVQHGQWQQHRYQ
241
504










Molecular Recognition Features






MoRF SequenceStartStop




NANANA