<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15320

Description Uncharacterized protein
SequenceMIDYSFKEELARTRERVEDLFYFESSKIGRGTYGLVYKATPKQPSVKYPAKEYALKLIEGQGFSMSACREIALLREMKHTNLICLQRVFLTNEKKVWLLLDYAEHDLWHIIKHHRNAKSKKTPVMVPKSMVKSILYQILDGIHYLHSNWILHRDLKPANILVMGDGPPNVRGRVKIADMGFARIFSNPLKPLAELDPVVVTFWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTSEPVFFCKEEDIKAQSPYHYDQLKRIFSVMGYPSEADWSDIKKMPDYQKLHMDLKNQNATFGSCSMQRYMEKYKIESETQQFKLLLKLLTMDPIKRISCKDAMEDNYFKTDPKPTEDVFYKFDIPYPKRDYLPENDVKKSHAMPTEEQNTNPPINQADSEPANKRMRVMNAHNNGSSIKIGGTSSGTMYGASGAQTQSIQVQQAASNNRPITSGQEMHLQGNNQMQGSGASDMQQPIGAMSNQQPPAHHMHQQNMQGMMQQPGHHQQFHPGQTQPQQMFQNQPMPAQMMQPQQTHPQPGHYPMGMMQNQQQQQQQQQQMMARQGAQGGHPHGQMGQAHPQMMGHGNQQAPPPYGMQNNDNMMMQGGQYMGQMQMGPGNNMNVQHGQWPQQHRYQ
Length628
PositionKinase
OrganismDiploscapter pachys
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Diploscapter.
Aromaticity0.08
Grand average of hydropathy-0.783
Instability index49.62
Isoelectric point8.93
Molecular weight71967.50
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15320
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     334.02|      37|      37|     495|     531|       1
---------------------------------------------------------------------------
  342-  393 (29.48/ 6.64)	.FKTDPKPTEdvFYKFD............IP....YPKrdylpendvkkshaMPT...EEQNTNPPINQADS
  394-  421 (29.52/ 6.65)	EPANKRMRVM..NAHNN............GS....SIK..............IGG............TSSGT
  422-  465 (37.55/10.38)	MYGASGAQTQ..SIQVQ............QAasnnRPI..............TSGqemHLQGNNQMQGSGAS
  466-  491 (43.53/13.15)	DMQ.QPIGA....MSNQ....................Q..............PPA...HH..MH..QQNMQG
  492-  511 (35.94/ 9.63)	MM.................................................qQPG...HHQQFHPGQTQPQQ
  512-  544 (66.03/23.59)	MFQNQPMPAQ..MMQPQ............QT....HPQ...............PG...H...YPMGMMQNQQ
  545-  588 (40.45/11.73)	..QQQQQQQQ..MMARQgaqgghphgqmgQA....HPQ..............MMG...HGNQQAP...PPYG
  589-  624 (51.52/16.86)	MQNNDNM.....MMQGG............QY....MGQ...........mqmGPG...NNMNVQHGQW.PQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.52|      33|      37|     114|     148|       2
---------------------------------------------------------------------------
  114-  148 (53.83/37.33)	HRNAKSKKTPVM..VPKSMVKSIlyQILD.GIHYLHSN
  152-  187 (49.69/28.20)	HRDLKPANILVMgdGPPNVRGRV..KIADmGFARIFSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.87|      22|      37|     192|     216|       3
---------------------------------------------------------------------------
  192-  216 (36.09/32.52)	LAEL...DPVvvtFWYRAPEL.LLGAKHY
  229-  254 (32.78/21.14)	FAELltsEPV...FFCKEEDIkAQSPYHY
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15320 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) YLPENDVKKSHAMPTEEQNTNPPINQADSEPANKRMRVMNAHNNGSSIKIGGTSSGTMYGASGAQTQSIQVQQAASNNRPITSGQEMHLQGNNQMQGSGASDMQQPIGAMSNQQPPAHHMHQQNMQGMMQQPGHHQQFHPGQTQPQQMFQNQPMPAQMMQPQQTHPQPGHYPMGMMQNQQQQQQQQQQMMARQGAQGGHPHGQMGQAHPQMMGHGNQQAPPPYGMQNNDNMMMQGGQYMGQMQMGPGNNMNVQHGQWPQQHRYQ
365
628










Molecular Recognition Features






MoRF SequenceStartStop




NANANA