<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15300

Description Uncharacterized protein
SequenceMSKEDEKNAEDDEYEQNLTGLPPTVTAMPYQSQECILYGTLHKEHLSDLERRISGLCDPGVEQFSEHEMAFSLRTGSTNPDVTIRLRRRFRQESFHTHQWQFRYIGMPEPDQKCPTIVRKVIDSVAYSPDMMHFAKTLGLRMDYEYMIKGSVWTCGKMKITAGSLQKTDKAGTYDKQFLKDVSDSYIIEISTSLPEQADYMPMSDEPSKVKEETGEISTGAEGSSESQQPILDIKQEGDVRDVGPRRNIRIAVAGCSHGEMDRIYETMAELEREEKQTFDLLVCCGDYQAVRNYGDLHHVNVPDKYRQLMTFYKYYSGEKVAPVLTLFVGGNHEASGFLAELPNGGWVAPKIYYMGYASVIRFAGLRIAGLSGIYGAKNFRKGHYERPPFGRDTIVTAYHVREVDVFRLKQLKPPDADESSNPIDIMISHDWPGGIYNYGNVDQLLRYKKHFKDDINSGRLGNPATMQVLQDIRPRYWFAAHLHCAFAAMVDHPSAAEPTRFLSLDKPIVRRHFLHSLEIEVKADVPQEDIEFSLSYDPHWLAILKSTDHFTRTDQTQVFMPSKKSVNERWDFRPNEDDIEEIRANKVKLHNVAPENYYRNPQTAKFCQWLGISDLNKMLIDLNPDEAVGLPYYMVKDSGDENEIKLDDSQDLDFGDDDFMLDNQGAGCGGCDESNDEGGEDADEAQGNGLGDFEAPKWKGNIAKGESNSAETAEQMQSAKVDEEGGLVLKRRKVDLQEEDD
Length742
PositionHead
OrganismDiploscapter pachys
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Diploscapter.
Aromaticity0.09
Grand average of hydropathy-0.670
Instability index47.05
Isoelectric point4.98
Molecular weight84287.32
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
hydrolase activity, acting on ester bonds	GO:0016788	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
mRNA processing	GO:0006397	IEA:UniProtKB-KW
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15300
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     156.83|      49|     290|     287|     338|       1
---------------------------------------------------------------------------
  287-  338 (84.17/69.08)	DYQAVR.NYGDLHHVNVPDKYR..QLMTFYKYYSGEKVAPVLtlfVGGN.HEASGF
  579-  631 (72.65/51.06)	DIEEIRaNKVKLHNVAPENYYRnpQTAKFCQWLGISDLNKML...IDLNpDEAVGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.05|      26|     368|       7|      34|       3
---------------------------------------------------------------------------
    7-   34 (41.72/31.60)	KNAEDDEYEQNLTGLPPTVTAmpYQSQE
  378-  403 (49.33/30.04)	KNFRKGHYERPPFGRDTIVTA..YHVRE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.29|      21|     264|     416|     436|       4
---------------------------------------------------------------------------
  416-  436 (41.01/24.90)	DADES.SNPIDIMISHDWPGGI
  682-  703 (35.29/20.44)	DADEAqGNGLGDFEAPKWKGNI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15300 with Med18 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NQGAGCGGCDESNDEGGEDADEAQGNGLGDFEAPKWKGNIAKGESNSAETAEQMQSAKVDEEGGLVLKRRKVDLQEEDD
2) QADYMPMSDEPSKVKEETGEISTGAEGSSESQQPILDIKQEGD
664
197
742
239










Molecular Recognition Features






MoRF SequenceStartStop




1) GDFEAPKWKGNIAKG
2) GGLVLKRRKVDLQ
692
726
706
738