<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15299

Description Uncharacterized protein
SequenceMSKEDEKNAEDDEYEQNLTGLPPTVTAMPYQSQECILYGTLHKEHLSDLERRISGLCDPGVEQFSEHEMAFSLRTGSANPDVTIRLRRRFRQESFHTHQWQFRYIGMPEPDQKCPTIVRKVIDSVAYSPDMMHFAKTLGLRMDYEYMIKGSVWTCGKMKITAGSLQKTDKAGTYDKQFLKDVSDSYIIEISTSLPEQADYMPMSEEPSKVKEEAGEISTGAEDAQAEGSSGNQQPILDIKQEGDVKEVGPRRKIRIAVAGCSHGEMDRIYETMAELEREEKQTFDLLICCGDYQAVRNYGDLHHVNVPDKYRQLMTFYKYYSGEKVAPVLTLFVGGNHEASGFLAELPNGGWVAPKIYYMGYASVIRFAGLRIAGLSGIYGAKNFRKGHYERPPFGRDTIVTAYHVREVDVFRLKQLRPPDADESSNPIDIMISHDWPGGIYNYGNVDQLLRYKKHFKDDIDSGRLGNPATMQVLQDIRPRYWFAAHLHCAFAAMVDHPSAAEPTRFLSLDKPIVRRHFLHSLEIEVKVDVPQEDIEFSLSYDPHWLAILKNTDHFTRTDQTQVFMPSKKSVSERWDFRPNEDDIEEIRTLGDLHVPENYEQTAAPTKAANKVKLYDVAPENYYRNPQTAKFCQWLGISDLNKMLIDLNPDEAVGLPYYMVKDSGDENEIKLDDSQDLDFGDDDFMLDNQGAGCGGSDGSNDEGGEDADEAQGNGLGDFEAPKWKGNIAKRESNSAETAEQMQSMKVDEEGGLVLKRRKVDLQEEDD
Length767
PositionHead
OrganismDiploscapter pachys
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Diploscapter.
Aromaticity0.09
Grand average of hydropathy-0.669
Instability index47.15
Isoelectric point4.95
Molecular weight87017.35
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
hydrolase activity, acting on ester bonds	GO:0016788	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
mRNA processing	GO:0006397	IEA:UniProtKB-KW
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15299
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.91|      11|      26|     593|     617|       1
---------------------------------------------------------------------------
  597-  607 (20.61/ 9.05)	PENYEQTAAPT
  620-  630 (21.30/18.48)	PENYYRNPQTA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.85|      25|      26|     190|     215|       2
---------------------------------------------------------------------------
  190-  215 (40.25/25.68)	ISTSLPE.QADYMPMSEEP.SKVKEEaG
  217-  243 (34.61/17.57)	ISTGAEDaQAEGSSGNQQPiLDIKQE.G
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.38|      19|      24|     673|     695|       3
---------------------------------------------------------------------------
  673-  695 (29.76/27.31)	DDSQDlDFGDD.DfmlDNQGAGCG
  698-  717 (32.62/16.77)	DGSND.EGGEDaD...EAQGNGLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.70|      19|      29|      62|      81|       4
---------------------------------------------------------------------------
   62-   81 (30.77/26.48)	EQFSEHEMAFSlRTGSANPD
   93-  111 (39.93/29.52)	ESFHTHQWQFR.YIGMPEPD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.96|       9|      25|     385|     394|       5
---------------------------------------------------------------------------
  385-  394 (15.79/11.74)	FRKGHYeRPP
  412-  420 (18.17/ 8.70)	FRLKQL.RPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.61|      15|      30|     496|     524|       6
---------------------------------------------------------------------------
  496-  513 (21.24/36.53)	VDHPSaaEPTRF.LSLDkP
  529-  544 (25.37/ 6.46)	VDVPQ..EDIEFsLSYD.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.72|      20|      25|     436|     457|       8
---------------------------------------------------------------------------
  436-  457 (35.80/30.04)	DWPGGiyNYGN.....VDQLLRYKKHF
  460-  484 (32.92/20.13)	DIDSG..RLGNpatmqVLQDIRPRYWF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.65|      12|     299|     292|     303|       9
---------------------------------------------------------------------------
  292-  303 (23.73/18.48)	DYQAVRNYGDLH
  584-  595 (21.93/16.43)	DIEEIRTLGDLH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15299 with Med18 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GDENEIKLDDSQDLDFGDDDFMLDNQGAGCGGSDGSNDEGGEDADEAQGNGLGDFEAPKWKGNIAKRESNSAETAEQMQSMKVDEEGGLVLKRRKVDLQEEDD
2) QADYMPMSEEPSKVKEEAGEISTGAEDAQAEGSSGNQQPILDIKQE
665
197
767
242










Molecular Recognition Features






MoRF SequenceStartStop




1) GDFEAPKWKGNIAKRE
2) LVLKRRKV
717
753
732
760